lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

Cross Reference

Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Acne Vulgaris D000152 35 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

Download all related citations
Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Straub P et al. Hydrophobic side chain requirements for lauric acid and progesterone hydroxylation at amino acid 113 in cytochrome P450 2C2, a potential determinant of substrate specificity. 1993 Arch. Biochem. Biophys. pmid:8215458
Carlson GP Formation of fatty acid propyl esters in liver, lung and pancreas of rats administered 1-propanol. 1993 Res. Commun. Chem. Pathol. Pharmacol. pmid:8210685
Kubo I et al. Naturally occurring antiacne agents. 1994 J. Nat. Prod. pmid:8158169
Hayes ML Reduction in acid tolerance of Streptococcus downeii by fluoride and potassium laurate. 1994 Caries Res. pmid:8156568
Hornung B et al. Lauric acid inhibits the maturation of vesicular stomatitis virus. 1994 J. Gen. Virol. pmid:8113756
Demarne Y et al. Effects of two different medium-chain triglycerides (tri C8:O and tri C12:O) on liver lipids in the growing rat. 1978 Arch. Int. Physiol. Biochim. pmid:80984
Amet Y et al. Evidence that cytochrome P450 2E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes. 1994 Biochem. Biophys. Res. Commun. pmid:8093035
Duncan T et al. A glycoprotein binding retinoids and fatty acids is present in Drosophila. 1994 Arch. Biochem. Biophys. pmid:8031123
Straub P et al. Differential effects of mutations in substrate recognition site 1 of cytochrome P450 2C2 on lauric acid and progesterone hydroxylation. 1994 Biochemistry pmid:8025107
Demarne Y et al. Comparison of long term lipogenic effects of two different medium-chain triglycerides (tri C8: O and tri C12 : O) in the growing rat. 1978 Arch. Int. Physiol. Biochim. pmid:80196
Mirsky VM Effect of the lipid hydrolysis products on the phospholipase A2 action towards lipid monolayer. 1994 Chem. Phys. Lipids pmid:8013058
Ronis MJ et al. Induction, suppression and inhibition of multiple hepatic cytochrome P450 isozymes in the male rat and bobwhite quail (Colinus virginianus) by ergosterol biosynthesis inhibiting fungicides (EBIFs). 1994 Biochem. Pharmacol. pmid:7986207
Nakamura M et al. Induction of cytochrome P450 isozymes in rat renal microsomes by cyclosporin A. 1994 Biochem. Pharmacol. pmid:7980643
Grundy SM Influence of stearic acid on cholesterol metabolism relative to other long-chain fatty acids. 1994 Am. J. Clin. Nutr. pmid:7977157
Shirakura S et al. Antithrombotic effects of KW-3635, a thromboxane A2-receptor antagonist, in guinea pigs. 1994 Jpn. J. Pharmacol. pmid:7967232
Mohan S and Raetz CR Endotoxin biosynthesis in Pseudomonas aeruginosa: enzymatic incorporation of laurate before 3-deoxy-D-manno-octulosonate. 1994 J. Bacteriol. pmid:7961456
Pavlova IuB et al. [Synthesis of photoreactive diglyceride--a protein kinase C ligand]. 1994 Bioorg. Khim. pmid:7945463
Komata Y et al. Effect of fatty acid on the accumulation of thiamine disulfide in rat skin. 1994 Biol. Pharm. Bull. pmid:7920438
Keegan FP and Blum JJ Incorporation of label from acetate and laurate into the mannan of Leishmania donovani via the glyoxylate cycle. 1993 Nov-Dec J. Eukaryot. Microbiol. pmid:7904877
Schwab US et al. Lauric and palmitic acid-enriched diets have minimal impact on serum lipid and lipoprotein concentrations and glucose metabolism in healthy young women. 1995 J. Nutr. pmid:7876922
Lee CK et al. Relationship between lipophilicity and skin permeability of various drugs from an ethanol/water/lauric acid system. 1994 Biol. Pharm. Bull. pmid:7874070
Preobrazhenskaia TA et al. [Comparative effect of polymyxin B on lipid bilayer membranes with different lipid composition]. 1994 Nov-Dec Biofizika pmid:7873621
Chaurasia CS et al. Biochemical characterization of lauric acid omega-hydroxylation by a CYP4A1/NADPH-cytochrome P450 reductase fusion protein. 1995 Arch. Biochem. Biophys. pmid:7872779
Ramarao MK et al. Identification by in vitro mutagenesis of the interaction of two segments of C2MstC1, a chimera of cytochromes P450 2C2 and P450 2C1. 1995 J. Biol. Chem. pmid:7829524
Redondo O et al. Comparative kinetic study of lipases A and B from Candida rugosa in the hydrolysis of lipid p-nitrophenyl esters in mixed micelles with Triton X-100. 1995 Biochim. Biophys. Acta pmid:7827103
Ling NC et al. Analogues of luteinizing hormone releasing factor modified at positions 2, 6, and 10. 1976 J. Med. Chem. pmid:781247
Hermansen JE Prediction of milk fatty acid profile in dairy cows fed dietary fat differing in fatty acid composition. 1995 J. Dairy Sci. pmid:7790578
Mustranta A et al. Applications of immobilized lipases to transesterification and esterification reactions in nonaqueous systems. 1993 Enzyme Microb. Technol. pmid:7763454
Lee CK et al. Transdermal delivery of theophylline using an ethanol/panasate 800-ethylcellulose gel preparation. 1995 Biol. Pharm. Bull. pmid:7735237
Clarke SE et al. Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes. 1994 Nov-Dec Chem. Res. Toxicol. pmid:7696540
Mensink RP et al. Dietary saturated and trans fatty acids and lipoprotein metabolism. 1994 Ann. Med. pmid:7695873
Mori T Biochemical properties of cultivated Mycobacterium lepraemurium. 1975 Jul-Sep Int. J. Lepr. Other Mycobact. Dis. pmid:767264
Geissdörfer W et al. Two genes encoding proteins with similarities to rubredoxin and rubredoxin reductase are required for conversion of dodecane to lauric acid in Acinetobacter calcoaceticus ADP1. 1995 Microbiology (Reading, Engl.) pmid:7670642
Abdel-Fattah G et al. Regulation of guinea pig very low density lipoprotein secretion rates by dietary fat saturation. 1995 J. Lipid Res. pmid:7665997
Smith SW and Anderson BD Human skin permeability enhancement by lauric acid under equilibrium aqueous conditions. 1995 J Pharm Sci pmid:7658343
Otten N et al. Experimental treatment of equine sarcoid using a xanthate compound and recombinant human tumour necrosis factor alpha. 1994 Zentralbl Veterinarmed A pmid:7653114
Motoyama Y et al. Effect of TFC-612, a 7-thia prostaglandin E1 derivative, on a peripheral arterial occlusive disease model in rats. 1995 Prostaglandins pmid:7652186
Faulkner KM et al. Electrocatalytically driven omega-hydroxylation of fatty acids using cytochrome P450 4A1. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7644480
Kromhout D et al. Dietary saturated and trans fatty acids and cholesterol and 25-year mortality from coronary heart disease: the Seven Countries Study. 1995 Prev Med pmid:7644455
Modi S et al. NMR studies of substrate binding to cytochrome P450 BM3: comparisons to cytochrome P450 cam. 1995 Biochemistry pmid:7619797
Takahashi N et al. Inhibition of in vitro aflatoxin B1-DNA binding in rainbow trout by CYP1A inhibitors: alpha-naphthoflavone, beta-naphthoflavone and trout CYP1A1 peptide antibody. 1995 Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. pmid:7599976
Knauf VC and Facciotti D Genetic engineering of foods to reduce the risk of heart disease and cancer. 1995 Adv. Exp. Med. Biol. pmid:7598011
Tholstrup T et al. Effect of fats high in individual saturated fatty acids on plasma lipoprotein[a] levels in young healthy men. 1995 J. Lipid Res. pmid:7595068
Pedersen AO et al. Effects of ionic strength and pH on the binding of medium-chain fatty acids to human serum albumin. 1995 Eur. J. Biochem. pmid:7588780
Floc'h F et al. Adjuvant and immunostimulating activities (in the absence of freund's incomplete adjuvant) of chemically modified low molecular weight mycobacterial peptidoglycans. 1978 Immunol. Commun. pmid:75834
Yeom H et al. The role of Thr268 in oxygen activation of cytochrome P450BM-3. 1995 Biochemistry pmid:7578081
Alterman MA et al. Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation. 1995 Biochem. Biophys. Res. Commun. pmid:7575514
Iwami Y et al. Effect of sucrose monolaurate on acid production, levels of glycolytic intermediates, and enzyme activities of Streptococcus mutans NCTC 10449. 1995 J. Dent. Res. pmid:7560425
Miura Y et al. An analysis of the fatty acid composition of total lipids from mycoplasmas. 1978 Jpn. J. Exp. Med. pmid:750678
Komata Y et al. Accumulation of lauric acid in skin as an enhancer for the percutaneous absorption of thiamine disulfide. 1995 Biol. Pharm. Bull. pmid:7493004