lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Acne Vulgaris D000152 35 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Per page 10 20 50 100 | Total 1837
Authors Title Published Journal PubMed Link
Okita RT et al. The omega- and (omega-1)-hydroxylase activities of prostaglandins A1 and E1 and lauric acid by pig kidney microsomes and a purified kidney cytochrome P-450. 1981 J. Biol. Chem. pmid:6787046
Viswanathan TS and Cushley RJ Deuterium nuclear magnetic resonance study of the interaction of substrates and inhibitors with soybean lipoxygenase. 1981 J. Biol. Chem. pmid:6788761
Miura Y Omega- and (omega-1)-hydroxylation of 1-dodecanol by frog liver microsomes. 1981 Lipids pmid:6975411
Benveniste I et al. Cytochrome P-450-Dependent omega-Hydroxylation of Lauric Acid by Microsomes from Pea Seedlings. 1982 Plant Physiol. pmid:16662431
Gibson WT Changes in epidermal acid phosphatase levels in response to chemical irritation. 1982 Br. J. Dermatol. pmid:7066188
Gibson GG et al. Cytochrome P-450 induction by clofibrate. Purification and properties of a hepatic cytochrome P-450 relatively specific for the 12- and 11-hydroxylation of dodecanoic acid (lauric acid). 1982 Biochem. J. pmid:7103935
Past MR and Cook DE Effect of diabetes on rat liver cytochrome P-450. Evidence for a unique diabetes-dependent rat liver cytochrome P-450. 1982 Biochem. Pharmacol. pmid:7150359
Qureshi N et al. Purification and structural determination of nontoxic lipid A obtained from the lipopolysaccharide of Salmonella typhimurium. 1982 J. Biol. Chem. pmid:6749846
Miura Y Effect of inhibitors on omega- and (omega-1)-hydroxylation of lauric acid by frog liver microsomes. 1982 Lipids pmid:6984479
Dell HD et al. Etofenamate fatty acid asters. An example of a new route of drug metabolism. 1982 Jan-Feb Drug Metab. Dispos. pmid:6124384
Orton TC and Parker GL The effect of hypolipidemic agents on the hepatic microsomal drug-metabolizing enzyme system of the rat. Induction of cytochrome(s) P-450 with specificity toward terminal hydroxylation of lauric acid. 1982 Mar-Apr Drug Metab. Dispos. pmid:6124394
Albers-Jackson B et al. Incorporation of 14C acetate into the phospholipids and fatty acids of rabbit lens in organ culture. 1982-1983 Curr. Eye Res. pmid:7184702
Wollenweber HW et al. Fatty acid in lipopolysaccharides of Salmonella species grown at low temperature. Identification and position. 1983 Eur. J. Biochem. pmid:6825685
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Jacobsen J and Brodersen R Albumin-bilirubin binding mechanism. 1983 J. Biol. Chem. pmid:6853485
Bogardus JB Liquid crystal solubilization of cholesterol: potential method for gallstone dissolution. 1983 J Pharm Sci pmid:6864466
Lake BG et al. Induction of lauric acid hydroxylation and maintenance of cytochrome P-450 content by clofibrate in primary cultures of rat hepatocytes. 1983 Life Sci. pmid:6865658
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Weisshaar R and Lingens F The lipopolysaccharide of a chloridazon-degrading bacterium. 1983 Eur. J. Biochem. pmid:6653551
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Qian X [Speech by Dr. Qian Xinzhong, Minister-in-charge of the State Family Planning Commission and Laureate of the United Nations Population Award, at the United Nations Population Award presentation ceremony (30 September 1983)]. 1983 Renkou Yanjiu pmid:12159402
Williams DE et al. Regiospecific hydroxylation of lauric acid at the (omega-1) position by hepatic and kidney microsomal cytochromes P-450 from rainbow trout. 1984 Arch. Biochem. Biophys. pmid:6732245
Leighton F et al. Peroxisomal fatty acid oxidation is selectively inhibited by phenothiazines in isolated hepatocytes. 1984 Biochem. Biophys. Res. Commun. pmid:6732769
Okita R and Chance C Induction of laurate omega-hydroxylase by di (2-ethylhexyl)phthalate in rat liver microsomes. 1984 Biochem. Biophys. Res. Commun. pmid:6732809
Salaun JP et al. Autocatalytic inactivation of plant cytochrome P-450 enzymes: selective inactivation of the lauric acid in-chain hydroxylase from Helianthus tuberosus L. by unsaturated substrate analogs. 1984 Arch. Biochem. Biophys. pmid:6742847
Lake BG et al. The effect of hypolipidaemic agents on peroxisomal beta-oxidation and mixed-function oxidase activities in primary cultures of rat hepatocytes. Relationship between induction of palmitoyl-CoA oxidation and lauric acid hydroxylation. 1984 Xenobiotica pmid:6711016
Lake BG et al. Comparative studies of the hepatic effects of di- and mono-n-octyl phthalates, di-(2-ethylhexyl) phthalate and clofibrate in the rat. 1984 Acta Pharmacol Toxicol (Copenh) pmid:6720315
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Lamikanra A and Sholola OA A study of the activity of soft soaps prepared from a homologous series of saturated fatty acids against cells of Escherichia coli NCTC 9001. 1984 Microbios pmid:6397680
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Tabatabai LB and Deyoe BL Biochemical and biological properties of soluble protein preparations from Brucella abortus. 1984 Dev. Biol. Stand. pmid:6436094
Lake BG et al. The effect of peroxisome proliferators on the metabolism and spectral interaction of endogenous substrates of cytochrome P-450 in rat hepatic microsomes. 1984 Life Sci. pmid:6439971
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Bugaut M et al. An examination of the stereochemical course of acylation of 2-monoacylglycerols by rat intestinal villus cells using [2H3]palmitic acid. 1984 Biochim. Biophys. Acta pmid:6696934
van der Valk PG et al. Skin irritancy of surfactants as assessed by water vapor loss measurements. 1984 J. Invest. Dermatol. pmid:6699429
Ortiz de Montellano PR and Reich NO Specific inactivation of hepatic fatty acid hydroxylases by acetylenic fatty acids. 1984 J. Biol. Chem. pmid:6706995