lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Acne Vulgaris D000152 35 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lauric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Authors Title Published Journal PubMed Link
Ruiz MB et al. Cholesterol ester hydrolysis in isolated rat liver cells. Effect of estradiol, dibutyryl cyclic AMP and free fatty acids. 1988 Horm. Metab. Res. pmid:2836287
Sato H et al. Multiple binding of bilirubin to human serum albumin and cobinding with laurate. 1988 Arch. Biochem. Biophys. pmid:2829743
Alves NF et al. Acute Treatment with Lauric Acid Reduces Blood Pressure and Oxidative Stress in Spontaneously Hypertensive Rats. 2017 Basic Clin. Pharmacol. Toxicol. pmid:28054477
Green PG et al. Enhanced in vitro skin permeation of cationic drugs. 1989 Pharm. Res. pmid:2798314
Beyer N et al. P450 fused to phosphite dehydrogenase allows phosphite-driven selective oxidations. 2017 Appl. Microbiol. Biotechnol. pmid:27900443
Albertini B et al. A novel approach for dry powder coating of pellets with Ethylcellulose. Part I: Evaluation of film formulation and process set up. 2017 Int J Pharm pmid:27894987
Han S et al. Structural insights into the binding of lauric acid to CYP107L2 from Streptomyces avermitilis. 2017 Biochem. Biophys. Res. Commun. pmid:27890614
Sharma RK et al. Differential induction of peroxisomal and microsomal fatty-acid-oxidising enzymes by peroxisome proliferators in rat liver and kidney. Characterisation of a renal cytochrome P-450 and implications for peroxisome proliferation. 1989 Eur. J. Biochem. pmid:2776771
Zhang L et al. Degradation Mechanisms of Polysorbate 20 Differentiated by O-labeling and Mass Spectrometry. 2017 Pharm. Res. pmid:27738952
Youngquist JT et al. Functional genomics analysis of free fatty acid production under continuous phosphate limiting conditions. 2017 J. Ind. Microbiol. Biotechnol. pmid:27738839
Kojima K et al. A simple method for isolation and construction of markerless cyanobacterial mutants defective in acyl-acyl carrier protein synthetase. 2016 Appl. Microbiol. Biotechnol. pmid:27704180
Lekshmi Sheela D et al. In Silico and Wet Lab Studies Reveal the Cholesterol Lowering Efficacy of Lauric Acid, a Medium Chain Fat of Coconut Oil. 2016 Plant Foods Hum Nutr pmid:27679437
Tambo F et al. Auto-oxidation of Lingula unguis and Siphonosoma cumanense hemerythrins induced by some perturbants. 1989 Biochem. Int. pmid:2764951
Bugaut M In vivo incorporation of lauric acid into rat adipose tissue triacylglycerols. 1989 Lipids pmid:2761351
Wada M et al. Mechanism of biosynthesis of unsaturated fatty acids in Pseudomonas sp. strain E-3, a psychrotrophic bacterium. 1989 J. Bacteriol. pmid:2753856
Christensen E et al. Beta-oxidation of medium chain (C8-C14) fatty acids studied in isolated liver cells. 1989 Biochim. Biophys. Acta pmid:2752017
Yuan Y et al. Coupling electrokinetics with microbial biodegradation enhances the removal of cycloparaffinic hydrocarbons in soils. 2016 J. Hazard. Mater. pmid:27501882
Gawas SD et al. Solvent Free Lipase Catalysed Synthesis of Ethyl Laurate: Optimization and Kinetic Studies. 2016 Appl. Biochem. Biotechnol. pmid:27470112
Ohhira S and Matsui H [Determination of dibutyltin compounds in polyvinyl chloride resin by capillary gas chromatography]. 1989 Nihon Eiseigaku Zasshi pmid:2746975
Huo Q et al. Molecular modification of proanthocyanidins. 2016 Bioengineered pmid:27459598
Dhers L et al. Spectral and 3D model studies of the interaction of orphan human cytochrome P450 2U1 with substrates and ligands. 2017 Biochim Biophys Acta Gen Subj pmid:27456766
Nonaka Y et al. Lauric Acid Stimulates Ketone Body Production in the KT-5 Astrocyte Cell Line. 2016 J Oleo Sci pmid:27430387
Holdfeldt A et al. The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)6-NH2 Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase. 2016 J. Biol. Chem. pmid:27422818
Karahaliloglu Z et al. Antibacterial chitosan/silk sericin 3D porous scaffolds as a wound dressing material. 2017 Artif Cells Nanomed Biotechnol pmid:27396677
Ryals PE et al. Lipid modification during cytodifferentiation of Tetrahymena vorax. Whole cell phospholipids and triacylglycerols of microstomal and macrostomal phenotypes. 1989 Biochim. Biophys. Acta pmid:2730920
Gyawali P et al. Determination of Ancylostoma caninum ova viability using metabolic profiling. 2016 Parasitol. Res. pmid:27236650
Frolov AF et al. Fatty acid composition of lipopolysaccharides of the strains of different species of Yersinia. 1989 J Hyg Epidemiol Microbiol Immunol pmid:2723424
Kupetz M et al. Impact of flavouring substances on the aggregation behaviour of dissolved barley β-glucans in a model beer. 2016 Carbohydr Polym pmid:27083361
Cerchiara T et al. Microparticles based on chitosan/carboxymethylcellulose polyelectrolyte complexes for colon delivery of vancomycin. 2016 Carbohydr Polym pmid:27083351
Weissenborn MJ et al. Whole-cell microtiter plate screening assay for terminal hydroxylation of fatty acids by P450s. 2016 Chem. Commun. (Camb.) pmid:27074906
Stucki JW et al. Acylation of proteins by myristic acid in isolated mitochondria. 1989 J. Biol. Chem. pmid:2703494
Hong Y et al. Photothermal ablation of cancer cells using self-doped polyaniline nanoparticles. 2016 Nanotechnology pmid:27010331
Rincón-Pérez J et al. Fatty Acids Profile, Phenolic Compounds and Antioxidant Capacity in Elicited Callus of Thevetia peruviana (Pers.) K. Schum. 2016 J Oleo Sci pmid:26972464
Uno T and Imai Y Identification of regions functioning in substrate interaction of rabbit liver cytochrome P-450 (laurate (omega-1)-hydroxylase). 1989 J. Biochem. pmid:2691506
Imai Y et al. Structure-function relationships of cytochrome P-450 laurate (omega-1)-hydroxylase. 1989 Drug Metab. Rev. pmid:2680391
Zhang W et al. Enhanced physicochemical properties of chitosan/whey protein isolate composite film by sodium laurate-modified TiO2 nanoparticles. 2016 Carbohydr Polym pmid:26794738
Lu Y et al. Impedance spectroscopy analysis of human odorant binding proteins immobilized on nanopore arrays for biochemical detection. 2016 Biosens Bioelectron pmid:26710343
Sanglard D and Loper JC Characterization of the alkane-inducible cytochrome P450 (P450alk) gene from the yeast Candida tropicalis: identification of a new P450 gene family. 1989 Gene pmid:2663647
Leakey JE et al. Effects of aging and caloric restriction on hepatic drug metabolizing enzymes in the Fischer 344 rat. I: The cytochrome P-450 dependent monooxygenase system. 1989 Mech. Ageing Dev. pmid:2661932
Mishima M et al. Promotion of nasal absorption of insulin by glycyrrhetinic acid derivatives. I. 1989 J. Pharmacobio-dyn. pmid:2656985
Graham SA Cuphea: a new plant source of medium-chain fatty acids. 1989 Crit Rev Food Sci Nutr pmid:2653730
Weng WH et al. Lauric acid can improve the sensitization of Cetuximab in KRAS/BRAF mutated colorectal cancer cells by retrievable microRNA-378 expression. 2016 Oncol. Rep. pmid:26496897
Haghikia A et al. Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine. 2015 Immunity pmid:26488817
Ogi K et al. Long-Chain Fatty Acids Elicit a Bitterness-Masking Effect on Quinine and Other Nitrogenous Bitter Substances by Formation of Insoluble Binary Complexes. 2015 J. Agric. Food Chem. pmid:26365517
Jarabak R and Westley J The sulfur-cyanolysis sites of serum albumin: metabolite competition studies. 1989 J. Biochem. Toxicol. pmid:2634097
Silva EL et al. Solid Lipid Nanoparticles Loaded with Retinoic Acid and Lauric Acid as an Alternative for Topical Treatment of Acne Vulgaris. 2015 J Nanosci Nanotechnol pmid:26328443
Yoon BK et al. Spectrum of Membrane Morphological Responses to Antibacterial Fatty Acids and Related Surfactants. 2015 Langmuir pmid:26325618
Laignelet L et al. Induction and inhibition of rat liver cytochrome(s) P-450 by an imidazole fungicide (prochloraz). 1989 Toxicology pmid:2631296
Zaloga J et al. Tangential Flow Ultrafiltration Allows Purification and Concentration of Lauric Acid-/Albumin-Coated Particles for Improved Magnetic Treatment. 2015 Int J Mol Sci pmid:26287178
Makowska JM et al. Species differences in the hepatic response to a potent peroxisome proliferator. 1989 Biochem. Soc. Trans. pmid:2628085
Kim YJ et al. Combination of nanoparticles with photothermal effects and phase-change material enhances the non-invasive transdermal delivery of drugs. 2015 Colloids Surf B Biointerfaces pmid:26277712
Zeitz JO et al. Effects of dietary fats rich in lauric and myristic acid on performance, intestinal morphology, gut microbes, and meat quality in broilers. 2015 Poult. Sci. pmid:26240391
Morisaki H [Inhibition of neutrophil function by solvent of injectable sedatives--effects of propylene glycol, ethanol and benzyl alcohol]. 1989 Masui pmid:2614886
Fu J et al. Camphor Tree Seed Kernel Oil Reduces Body Fat Deposition and Improves Blood Lipids in Rats. 2015 J. Food Sci. pmid:26130050
He T et al. Hypoxia-inducible factor-1α expression in the different stages of rat thromboangiitis obliterans. 2015 Genet. Mol. Res. pmid:26125880
Ma X et al. Acylation of Antioxidant of Bamboo Leaves with Fatty Acids by Lipase and the Acylated Derivatives' Efficiency in the Inhibition of Acrylamide Formation in Fried Potato Crisps. 2015 PLoS ONE pmid:26098744
Yokotani N et al. Two forms of omega-hydroxylase toward prostaglandin A and laurate. cDNA cloning and their expression. 1989 J. Biol. Chem. pmid:2600085
Wong KL et al. Dietary cis-fatty acids that increase protein F1 phosphorylation enhance spatial memory. 1989 Brain Res. pmid:2598047
Kocarek TA and Feller DR Quantitative assessment of enzyme induction by peroxisome proliferators and application to determination of effects on triglyceride biosynthesis in primary cultures of rat hepatocytes. 1989 Biochem. Pharmacol. pmid:2597188
Zaloga J et al. Different storage conditions influence biocompatibility and physicochemical properties of iron oxide nanoparticles. 2015 Int J Mol Sci pmid:25918940
El Ayeb-Zakhama A et al. Chemical composition and allelopathic potential of essential oils obtained from Acacia cyanophylla Lindl. Cultivated in Tunisia. 2015 Chem. Biodivers. pmid:25879505
Yamashita S et al. Identification of self-growth-inhibiting compounds lauric acid and 7-(Z)-tetradecenoic acid from Helicobacter pylori. 2015 Microbiology (Reading, Engl.) pmid:25767109
Sonwai S et al. Lauric fat cocoa butter replacer from krabok (irvingia malayana) seed fat and coconut oil. 2015 J Oleo Sci pmid:25766934
Yamamoto Y et al. Palmitoleic acid calcium salt: a lubricant and bactericidal powder from natural lipids. 2015 J Oleo Sci pmid:25757432
Sengupta A et al. Production of medium chain fatty acid rich mustard oil using packed bed bioreactor. 2015 J Oleo Sci pmid:25748375
Krzan M et al. Effect of products of PLA2 catalyzed hydrolysis of DLPC on motion of rising bubbles. 2015 Colloids Surf B Biointerfaces pmid:25724770
Woolfrey SG et al. The effect of Miglycol 812 oil on the oral absorption of propranolol in the rat. 1989 J. Pharm. Pharmacol. pmid:2571709
Leon W et al. Fatty acid composition of amastigote and trypomastigote forms of Trypanosoma cruzi. 1989 Acta Trop. pmid:2565074
Wu B et al. Broad hexagonal columnar mesophases formation in bioinspired transition-metal complexes of simple fatty acid meta-octaester derivatives of meso-tetraphenyl porphyrins. 2015 Chemistry pmid:25619819
Fibach E et al. Analysis of cellular heterogeneity in the response of human leukemic cells to photosensitization induced by pyrene-containing fatty acid. 1989 Leuk. Res. pmid:2559259
Totland C et al. Composition and structural transitions of polyelectrolyte-surfactant complexes in the presence of fatty acid studied by NMR and cryo-SEM. 2015 Langmuir pmid:25590530
Zeng C et al. Enzymatic synthesis of phytosterol esters catalyzed by Candida rugosa lipase in water-in-[Bmim]PF6 microemulsion. 2015 Bioprocess Biosyst Eng pmid:25575761
Sharma RK et al. Role of hepatic and renal cytochrome P-450 IVA1 in the metabolism of lipid substrates. 1989 Biochem. Pharmacol. pmid:2554928
Goodwin D et al. Stability, permeability and growth-inhibitory properties of gonadotropin-releasing hormone liposaccharides. 2015 Pharm. Res. pmid:25407542
He WS et al. Efficient synthesis and characterization of ergosterol laurate in a solvent-free system. 2014 J. Agric. Food Chem. pmid:25405492
Radice M et al. Chemical characterization and antioxidant activity of Amazonian (Ecuador) Caryodendron orinocense Karst. and Bactris gasipaes Kunth seed oils. 2014 J Oleo Sci pmid:25391685
Zaloga J et al. Development of a lauric acid/albumin hybrid iron oxide nanoparticle system with improved biocompatibility. 2014 Int J Nanomedicine pmid:25364244
Miranda CL et al. Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout. 1989 Arch. Biochem. Biophys. pmid:2536262
Sengupta A et al. Antioxidative effect of rice bran oil and medium chain fatty acid rich rice bran oil in arsenite induced oxidative stress in rats. 2014 J Oleo Sci pmid:25354877
Xu L et al. Loading capacity and interaction of DNA binding on catanionic vesicles with different cationic surfactants. 2014 Soft Matter pmid:25317547
Kim D et al. Kinetic analysis of lauric acid hydroxylation by human cytochrome P450 4A11. 2014 Biochemistry pmid:25203493
Jamuna-Thevi K et al. Triple-layered PLGA/nanoapatite/lauric acid graded composite membrane for periodontal guided bone regeneration. 2014 Mater Sci Eng C Mater Biol Appl pmid:25175212
Adarchenko AA et al. [Antiseptic sensitivity of clinical strains of Pseudomonas aeruginosa]. 1989 Antibiot. Khimioter. pmid:2517004
Lau SC et al. Enhanced biocatalytic esterification with lipase-immobilized chitosan/graphene oxide beads. 2014 PLoS ONE pmid:25127038
Murai T et al. Effect of beraprost sodium on peripheral circulation insufficiency in rats and rabbits. 1989 Arzneimittelforschung pmid:2510741
Chang F et al. Effects of heat treatment and moisture contents on interactions between lauric acid and starch granules. 2014 J. Agric. Food Chem. pmid:25056554
Mukwevho E and Joseph JS Calmodulin dependent protein kinase II activation by exercise regulates saturated & unsaturated fatty acids and improves some metabolic syndrome markers. 2014 Life Sci. pmid:25046734
Imaoka S et al. Omega- and (omega-1)-hydroxylation of lauric acid and arachidonic acid by rat renal cytochrome P-450. 1989 Biochem. Int. pmid:2504167
Modolon Sde M et al. Self-association of sodium deoxycholate with EHEC cellulose cooperatively induced by sodium dodecanoate. 2014 Carbohydr Polym pmid:25037371
Thomas OR and White GF Metabolic pathway for the biodegradation of sodium dodecyl sulfate by Pseudomonas sp. C12B. 1989 Biotechnol. Appl. Biochem. pmid:2503014
Arcan I and YemenicioÄŸlu A Controlled release properties of zein-fatty acid blend films for multiple bioactive compounds. 2014 J. Agric. Food Chem. pmid:25025594
Boiteux-Antoine AF et al. Comparative induction of drug-metabolizing enzymes by hypolipidaemic compounds. 1989 Gen. Pharmacol. pmid:2502468
Dai C et al. Formation of worm-like micelles in mixed N-hexadecyl-N-methylpyrrolidinium bromide-based cationic surfactant and anionic surfactant systems. 2014 PLoS ONE pmid:25019152
Thomas H et al. Effect of hypolipidemic compounds on lauric acid hydroxylation and phase II enzymes. 1989 Biochem. Pharmacol. pmid:2500933
Pham MA et al. Characterization of distinct forms of cytochromes P-450, epoxide metabolizing enzymes and UDP-glucuronosyltransferases in rat skin. 1989 Biochem. Pharmacol. pmid:2500129
Fink AS et al. Intraluminal calcium binding does not mediate fatty acid-induced pancreatic bicarbonate secretion. 1989 Int. J. Pancreatol. pmid:2499642
Benveniste I et al. Immunochemical characterization of NADPH-cytochrome P-450 reductase from Jerusalem artichoke and other higher plants. 1989 Biochem. J. pmid:2499315
Lake BG et al. Comparative studies on nafenopin-induced hepatic peroxisome proliferation in the rat, Syrian hamster, guinea pig, and marmoset. 1989 Toxicol. Appl. Pharmacol. pmid:2499080
Aarsaether N et al. Changes in peroxisomes and mitochondria in liver of ethionine exposed rats: a biochemical and morphological investigation. 1989 Carcinogenesis pmid:2498002
Borlakoglu JT et al. Evidence for the induction of cytochrome P-452 in rat liver by Aroclor 1254, a commercial mixture of polychlorinated biphenyls. 1989 FEBS Lett. pmid:2497034