| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sengupta R et al. | Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions. | 2015 | Oncotarget | pmid:26286961 |
| Gu G et al. | Efficient one-pot synthesis of tigogenin saponins and their antitumor activities. | 2014 | Carbohydr. Res. | pmid:24239606 |
| Li J et al. | Reversal of dopamine neurons and locomotor ability degeneration in aged rats with smilagenin. | 2013 | Neuroscience | pmid:23624370 |
| Sánchez-Flores J et al. | Diacetoxyiodobenzene-mediated synthesis of unnatural furospirostane sapogenins derived from diosgenin and tigogenin. | 2013 | Steroids | pmid:23707570 |
| Shen S et al. | Sarsasapogenin induces apoptosis via the reactive oxygen species-mediated mitochondrial pathway and ER stress pathway in HeLa cells. | 2013 | Biochem. Biophys. Res. Commun. | pmid:24383086 |
| López Y et al. | Regioselective cleavage of 22-oxo-23-spiroketals. Novel cholestanic frameworks with pyranone and cyclopentenone E rings on the side chain. | 2012 | Steroids | pmid:22333396 |
| Zhang R et al. | Smilagenin attenuates beta amyloid (25-35)-induced degeneration of neuronal cells via stimulating the gene expression of brain-derived neurotrophic factor. | 2012 | Neuroscience | pmid:22441042 |
| Wang L et al. | Simultaneous analysis of diosgenin and sarsasapogenin in Asparagus officinalis byproduct by thin-layer chromatography. | 2011 Jan-Feb | Phytochem Anal | pmid:20799270 |
| Sidiq T et al. | A novel sarsasapogenin glycoside from Asparagus racemosus elicits protective immune responses against HBsAg. | 2011 | Immunol. Lett. | pmid:21035507 |
| Xiao SF et al. | A double-blind, placebo-controlled study of traditional Chinese medicine sarsasapogenin added to risperidone in patients with negative symptoms dominated schizophrenia. | 2011 | Neurosci Bull | pmid:21788997 |
| Wang J et al. | A sensitive indirect competitive enzyme-linked immunosorbent assay for the detection of sarsasapogenin in rat plasma. | 2010 | Acta Pharmacol. Sin. | pmid:20686523 |
| Hu H et al. | Role of CREB in the regulatory action of sarsasapogenin on muscarinic M1 receptor density during cell aging. | 2010 | FEBS Lett. | pmid:20214903 |
| Lee B et al. | Inhibitory effects of steroidal timosaponins isolated from the rhizomes of Anemarrhena asphodeloides against passive cutaneous anaphylaxis reaction and pruritus. | 2010 | Immunopharmacol Immunotoxicol | pmid:20095799 |
| Hu Y et al. | Regulation of M1-receptor mRNA stability by smilagenin and its significance in improving memory of aged rats. | 2010 | Neurobiol. Aging | pmid:18676061 |
| Hernández-Linares MG et al. | Deacylation reactions of 20-acetyl dinorcholanic lactones and 20,23-diacetyl furost-22-enes. | 2010 | Steroids | pmid:20034505 |
| Czajkowska D et al. | Synthesis of "glycospirostanes" via ring-closing metathesis. | 2009 Nov-Dec | Steroids | pmid:19748518 |
| Valadares YM et al. | Antiviral activity of Solanum paniculatum extract and constituents. | 2009 Nov-Dec | Z. Naturforsch., C, J. Biosci. | pmid:20158151 |
| Cigerci IH et al. | The protective potential of Yucca schidigera (Sarsaponin 30) against nitrite-induced oxidative stress in rats. | 2009 | J Nat Med | pmid:19434470 |
| Li T et al. | An improved facile method for extraction and determination of steroidal saponins in Tribulus terrestris by focused microwave-assisted extraction coupled with GC-MS. | 2009 | J Sep Sci | pmid:19890844 |
| Sa F et al. | Anti-proliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines. | 2008 | Chem. Biol. Interact. | pmid:17996228 |
| Zhang Y et al. | Role of glial cell derived neurotrophic factor in the protective effect of smilagenin on rat mesencephalic dopaminergic neurons damaged by MPP+. | 2008 | FEBS Lett. | pmid:18298955 |
| Ni Y et al. | Mitochondrial ROS burst as an early sign in sarsasapogenin-induced apoptosis in HepG2 cells. | 2008 | Cell Biol. Int. | pmid:18262806 |
| Visanji NP et al. | PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease. | 2008 | FASEB J. | pmid:18364399 |
| Huang XF et al. | Steroids from the roots of Asparagus officinalis and their cytotoxic activity. | 2008 | J Integr Plant Biol | pmid:18713412 |
| Yan H et al. | Treating senile dementia with traditional Chinese medicine. | 2007 | Clin Interv Aging | pmid:18044136 |
| Chen J et al. | [Studies on accumulation of active ingredients, N, P and K in Anemarrhena asphodeloides]. | 2007 | Zhongguo Zhong Yao Za Zhi | pmid:17972573 |
| Ren LX et al. | Antidepressant activity of sarsasapogenin from Anemarrhena asphodeloides Bunge (Liliaceae). | 2007 | Pharmazie | pmid:17294820 |
| Bao W et al. | The apoptotic effect of sarsasapogenin from Anemarrhena asphodeloides on HepG2 human hepatoma cells. | 2007 | Cell Biol. Int. | pmid:17400003 |
| Liagre B et al. | Inhibition of human rheumatoid arthritis synovial cell survival by hecogenin and tigogenin is associated with increased apoptosis, p38 mitogen-activated protein kinase activity and upregulation of cyclooxygenase-2. | 2007 | Int. J. Mol. Med. | pmid:17786275 |
| Zhou H et al. | Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells. | 2007 | Mol. Cell. Endocrinol. | pmid:17363141 |
| Cheeke PR et al. | Anti-inflammatory and anti-arthritic effects of Yucca schidigera: a review. | 2006 | J Inflamm (Lond) | pmid:16571135 |
| Ren LX et al. | Antidepressant-like effects of sarsasapogenin from Anemarrhena asphodeloides BUNGE (Liliaceae). | 2006 | Biol. Pharm. Bull. | pmid:17077534 |
| Hu Y et al. | A new approach to the pharmacological regulation of memory: Sarsasapogenin improves memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models. | 2005 | Brain Res. | pmid:16226729 |
| Trouillas P et al. | Structure-function relationship for saponin effects on cell cycle arrest and apoptosis in the human 1547 osteosarcoma cells: a molecular modelling approach of natural molecules structurally close to diosgenin. | 2005 | Bioorg. Med. Chem. | pmid:15670922 |
| Merlani MI et al. | [Synthesis from tigogenin and antituberculosis activity of some of the derivatives of 5alpha-ketosteroid hydrazones]. | 2004 Sep-Oct | Bioorg. Khim. | pmid:15562978 |
| Uematsu Y et al. | Investigation of spectrophotometrically determined substances in Yucca extract by GC/MS, TLC and on-column injection GC. | 2004 | Shokuhin Eiseigaku Zasshi | pmid:15468933 |
| Nawłoka P et al. | Evidence for essential histidine and dicarboxylic amino-acid residues in the active site of UDP-glucose : solasodine glucosyltransferase from eggplant leaves. | 2003 | Acta Biochim. Pol. | pmid:12833182 |
| Corbiere C et al. | Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids, hecogenin and tigogenin, on human 1547 osteosarcoma cells. | 2003 | Int. J. Oncol. | pmid:12632085 |
| Loader JI et al. | Ovine metabolism of lithogenic sapogenins. Synthesis of [2,2,4,4-(2)h(4)]sarsasapogenone, [2,2,4,4-(2)h(4)]sarsasapogenin, and [2,2,4,4-(2)h(4)]episarsasapogenin and evaluation of deuterium retention in a sheep-dosing trial. | 2003 | J. Agric. Food Chem. | pmid:12696951 |
| Sandoval-RamÃrez J et al. | Regioselective cleavage of rings E and F in sarsasapogenin. | 2003 | Steroids | pmid:12606011 |
| Lila ZA et al. | Effect of sarsaponin on ruminal fermentation with particular reference to methane production in vitro. | 2003 | J. Dairy Sci. | pmid:14594252 |
| Pazkowski C et al. | Phospholipids modulate the substrate specificity of soluble UDP-glucose:steroid glucosyltransferase from eggplant leaves. | 2001 | Phytochemistry | pmid:11672729 |
| Yu B et al. | [Determination of sarsasapogenin in "tian dong" by TLCS]. | 2001 | Zhong Yao Cai | pmid:11715195 |
| Ma D et al. | Effect of sarsasapogenin and its derivatives on the stimulus coupled responses of human neutrophils. | 2001 | Clin. Chim. Acta | pmid:11718685 |
| Flåøyen A et al. | Ovine metabolism of saponins: evaluation of a method for estimating the ovine uptake of steroidal saponins from Narthecium ossifragum. | 2001 | Vet. Res. Commun. | pmid:11334151 |
| Ji HW et al. | [Screening of steroidal saponins from the bulbs of Lilium brownii var. colchesteri by combination of high performance liquid chromatography-electrospray ionization mass spectrometry and electron impact mass spectrometry]. | 2001 | Se Pu | pmid:12545433 |
| Cruz C et al. | Isolation of steroidal sapogenins implicated in experimentally induced cholangiopathy of sheep grazing Brachiaria decumbens in Brazil. | 2000 | Vet Hum Toxicol | pmid:10839316 |
| Liu Y et al. | [Determination of sarsasapogenin in Anemarrhena asphodeloides Bunge by GC]. | 1999 | Zhongguo Zhong Yao Za Zhi | pmid:12205902 |
| Sen S et al. | Effect of Quillaja saponaria saponins and Yucca schidigera plant extract on growth of Escherichia coli. | 1998 | Lett. Appl. Microbiol. | pmid:9722995 |
| Zinn RA et al. | Influence of tempering on the feeding value of rolled corn in finishing diets for feedlot cattle. | 1998 | J. Anim. Sci. | pmid:9781478 |
| Agrawal PK et al. | Dependence of the 1H NMR chemical shifts of ring F resonances on the orientation of the 27-methyl group of spirostane-type steroidal sapogenins. | 1998 | Phytochemistry | pmid:9431674 |
| Lee SS et al. | Microbial transformation of dihydrosarsasapogenin with Mycobacterium sp. | 1998 | J. Nat. Prod. | pmid:9514011 |
| Peana AT et al. | Anti-inflammatory activity of aqueous extracts and steroidal sapogenins of Agave americana. | 1997 | Planta Med. | pmid:9225599 |
| Wu Z et al. | Influence of yucca extract on ruminal metabolism in cows. | 1994 | J. Anim. Sci. | pmid:8014138 |
| Han GR et al. | [Quality of rhizoma Anemarrhenae grown for different periods of time and gathered in different seasons]. | 1993 | Zhongguo Zhong Yao Za Zhi | pmid:8011092 |
| Lajis NH et al. | Epi-sarsasapogenin and epi-smilagenin: two sapogenins isolated from the rumen content of sheep intoxicated by Brachiaria decumbens. | 1993 | Steroids | pmid:8212090 |
| Flåøyen A et al. | Cladosporium magnusianum (Jaap) M.B. Ellis is probably not involved in alveld. | 1993 | Vet. Res. Commun. | pmid:7904389 |
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| Saito S et al. | The reactions of beta- and alpha-pyranose peracetates with PCl5, and utilization of the products to construct sarsasapogenin glycosides. | 1992 | Chem. Pharm. Bull. | pmid:1294329 |
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| MARKER RE | Steroidal sapogenins; magogenin and cacogenin and their biogenesis to chlorogenin and tigogenin. | 1947 | J. Am. Chem. Soc. | pmid:20268295 |
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(25R)-5beta-spirostan-3beta-ol
(25r)-5beta-spirostan-3beta-ol is a lipid of Sterol Lipids (ST) class.
Cross Reference
