Diosgenin

Diosgenin is a lipid of Sterol Lipids (ST) class. Diosgenin is associated with abnormalities such as Diabetes, PARAGANGLIOMAS 3, Osteoporosis, estrogen deficiency and Bone Diseases. The involved functions are known as Process, inhibitors, Metabolic Inhibition, Diastasis and Inflammation. Diosgenin often locates in Hepatic, Extracellular, Body tissue, Entire bony skeleton and Cytoplasmic matrix. The associated genes with Diosgenin are SLC2A1 gene, Operator gene, CFB gene, IMPACT gene and iberiotoxin. The related lipids are Saponins, Saponin, Steroids, Sapogenins and yamogenin.

Cross Reference

Introduction

To understand associated biological information of Diosgenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Diosgenin?

Diosgenin is suspected in Osteoporosis, Vascular Diseases, Anemia, Sickle Cell, Diabetes, Dyslipidemias, PARAGANGLIOMAS 3 and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Diosgenin

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Diosgenin

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Diosgenin through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Diosgenin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Diosgenin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Diosgenin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Diosgenin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Diosgenin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Diosgenin

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Authors Title Published Journal PubMed Link
pmid:
Amigo L et al. Enrichment of canalicular membrane with cholesterol and sphingomyelin prevents bile salt-induced hepatic damage. 1999 J. Lipid Res. pmid:10064742
Hooiveld GJ et al. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats. 1999 Gastroenterology pmid:10464145
Deng S et al. Synthesis of three diosgenyl saponins: dioscin, polyphyllin D, and balanitin 7. 1999 Carbohydr. Res. pmid:10466206
Laurila J et al. Determination of solanidine- and tomatidine-type glycoalkaloid aglycons by gas Chromatography/Mass spectrometry. 1999 J. Agric. Food Chem. pmid:10552556
Timmons BW et al. The efficacy of SPORT as a dietary supplement on performance and recovery in trained athletes. 2000 Can J Appl Physiol pmid:10683600
Driedger DR et al. A capillary electrophoresis laser-induced fluorescence method for analysis of potato glycoalkaloids based on a solution-phase immunoassay. 1. Separation and quantification of immunoassay products. 2000 J. Agric. Food Chem. pmid:10775362
Scott A et al. TCPL drug delivery system: the effects of synthetic DHEA and Diosgenin using an ovariectomized rat model. 2000 Biomed Sci Instrum pmid:10834228
Bednarczyk D et al. The synthesis of diosgenyl 2-amino-2-deoxy-beta-D-glucopyranoside hydrochloride. 2000 Carbohydr. Res. pmid:11072831
Taylor WG et al. Microdetermination of diosgenin from fenugreek (Trigonella foenum-graecum) seeds. 2000 J. Agric. Food Chem. pmid:11087460