Scillarenin 3-o-rhamnoside

Scillarenin 3-o-rhamnoside is a lipid of Sterol Lipids (ST) class.

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Current reference collection contains 174 references associated with Scillarenin 3-o-rhamnoside in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Okuyama-Dobashi K et al. Hepatitis B virus efficiently infects non-adherent hepatoma cells via human sodium taurocholate cotransporting polypeptide. 2015 Sci Rep pmid:26592202
Denicolaï E et al. Proscillaridin A is cytotoxic for glioblastoma cell lines and controls tumor xenograft growth in vivo. 2014 Oncotarget pmid:25400117
El-Seedi HR et al. The traditional medical uses and cytotoxic activities of sixty-one Egyptian plants: discovery of an active cardiac glycoside from Urginea maritima. 2013 J Ethnopharmacol pmid:23228916
Winnicka K et al. Inhibition of DNA topoisomerases I and II by G3 PAMAM-NH2 dendrimer-modified digoxin and proscillaridin A conjugates in a cell free system. 2010 Nov-Dec Acta Pol Pharm pmid:21229879
Winnicka K et al. Synthesis and cytotoxic activity of G3 PAMAM-NH(2) dendrimer-modified digoxin and proscillaridin A conjugates in breast cancer cells. 2010 Mar-Apr Pharmacol Rep pmid:20508299
Winnicka K et al. Dual effects of ouabain, digoxin and proscillaridin A on the regulation of apoptosis in human fibroblasts. 2010 Nat. Prod. Res. pmid:20140806
Felth J et al. Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs. 2009 J. Nat. Prod. pmid:19894733
Winnicka K et al. Antiproliferative activity of derivatives of ouabain, digoxin and proscillaridin A in human MCF-7 and MDA-MB-231 breast cancer cells. 2008 Biol. Pharm. Bull. pmid:18520043
Winnicka K et al. Apoptosis-mediated cytotoxicity of ouabain, digoxin and proscillaridin A in the estrogen independent MDA-MB-231 breast cancer cells. 2007 Arch. Pharm. Res. pmid:18038900
Bielawski K et al. Inhibition of DNA topoisomerases I and II, and growth inhibition of breast cancer MCF-7 cells by ouabain, digoxin and proscillaridin A. 2006 Biol. Pharm. Bull. pmid:16819197
Terness P et al. Exquisitely small amounts of nonglucocorticoid natural steroids suppress the human allogeneic T-cell response. 2001 Feb-Mar Transplant. Proc. pmid:11266951
Kodama-Takahashi K et al. [An elderly case of idiopathic dilatation of the right atrium in which right-sided heart failure was exacerbated by drug-induced bradyarrhythmia]. 2001 Nihon Ronen Igakkai Zasshi pmid:11523170
Terness P et al. The T-cell suppressive effect of bufadienolides: structural requirements for their immunoregulatory activity. 2001 Int. Immunopharmacol. pmid:11367509
Schneider R et al. Proscillaridin A immunoreactivity: its purification, transport in blood by a specific binding protein and its correlation with blood pressure. 1998 Jul-Aug Clin. Exp. Hypertens. pmid:9682915
Li S et al. Bovine adrenals and hypothalamus are a major source of proscillaridin A- and ouabain-immunoreactivities. 1998 Life Sci. pmid:9515560
Li SQ et al. Proscillaridin A immunoreactivity: a new endogenous cardiac glycoside? 1997 Ann. N. Y. Acad. Sci. pmid:9405880
Nguyen AT and Doris PA Role of endogenous cardiac glycosides in the spontaneously hypertensive rat--antagonism by active immunization. 1996 Am. J. Hypertens. pmid:8834711
Sich B et al. Pulse pressure correlates in humans with a proscillaridin A immunoreactive compound. 1996 Hypertension pmid:8621199
Tanase T et al. Cardiac glycoside-induced elevation of intracellular Na+ ion concentration in human erythrocytes studied by 23Na NMR spectroscopy: relationship between inotropy speed and elevation rate of intracellular Na+ ion concentration. 1993 Biol. Pharm. Bull. pmid:8358396
Okamoto M and Tsukahara T [Preparation of phenylpropylsilica and its application to high performance liquid chromatographic analysis of proscillaridin]. 1993 Yakugaku Zasshi pmid:8387581
Tanase T et al. Studies on cardiac ingredients of plants. IX. Chemical transformation of proscillaridin by utilizing its 1,4-cycloadducts as key compounds and biological activities of their derivatives. 1992 Chem. Pharm. Bull. pmid:1318790
Tanase T et al. [Studies on cardiac ingredients of plants. X. Preparation of nitrates of tetrahydroproscillaridin and their pharmacological activities]. 1992 Yakugaku Zasshi pmid:1336548
Murakami N et al. [Studies on cardiac ingredients of plants. VIII. Preparation of nitrates of proscillaridin and their pharmacological activities]. 1991 Yakugaku Zasshi pmid:1665512
Murakami N et al. Studies on cardiac ingredients of plants. VII: Chemical transformation of proscillaridin by means of the Diels-Alder reaction and biological activities of its derivatives. 1991 Chem. Pharm. Bull. pmid:1839142
Sabouraud A et al. Specific anti-digoxin Fab fragments: an available antidote for proscillaridin and scilliroside poisoning? 1990 Hum Exp Toxicol pmid:2375888
Mori J et al. Studies on cardiac ingredients of plants. V. Chemical transformation of proscillaridin and biological activities of derivatives. 1988 Chem. Pharm. Bull. pmid:3378308
Bonelli J et al. Hemodynamic effect of methylepoxyproscillaridin (P35) in patients with congestive myocardiopathy. 1988 Int J Clin Pharmacol Ther Toxicol pmid:3410600
Bonelli J et al. The bioavailability of methylepoxyproscillaridin (P35): a new semisynthetic cardiac glycoside. 1988 Int J Clin Pharmacol Ther Toxicol pmid:3410606
Mori J et al. Studies on cardiac ingredients of plants. III. Structural confirmation and biological activity of reduced proscillaridins. 1987 Chem. Pharm. Bull. pmid:2822265
Sakakibara J et al. [Studies on cardiac ingredients of plants (IV). Effect of reduced proscillaridins on guinea-pig hearts]. 1987 Nippon Yakurigaku Zasshi pmid:3679019
Kojima K et al. Determination of proscillaridin in plasma by radioimmunoassay. 1986 J. Pharmacobio-dyn. pmid:3783410
Röder E and Lütz J [Potential radiopharmaceutical for adrenal gland scintigraphy. 1. Radioiodination of tyramine derivatives of some derivatives of digitoxigenin and scillarenin]. 1985 Arch. Pharm. (Weinheim) pmid:4084030
Franco PD et al. [Use of a cardiotonic agent in the ventricular pre-excitation syndrome. Report of a case]. 1985 Arq. Bras. Cardiol. pmid:4096667
Alken RG and Belz GG A comparative dose-effect study with cardiac glycosides assessing cardiac and extracardiac responses in normal subjects. 1984 Jul-Aug J. Cardiovasc. Pharmacol. pmid:6206318
Burkert K and Beckmann H [Plasma concentration and elimination behavior of the cardiac glycoside meproscillarin in patients with liver cirrhosis]. 1983 Z Gastroenterol pmid:6845784
Lüllmann H et al. Electrophysiological studies of some semisynthetic cardiac glycoside derivatives in isolated papillary muscle of the guinea-pig. 1983 Br. J. Pharmacol. pmid:6652355
Brock N et al. Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna). 1982 Eur J Cancer Clin Oncol pmid:6819957
Tytman B [Evaluation of the practical use of mathematical methods and computer technics for the control of treatment with selected digitalis glycosides]. 1981 Pol Tyg Lek pmid:7335534
Ferrer M et al. [Densitometric determination of proscillaridin A, scillaren A and scilliroside]. 1980 Farmaco Prat pmid:7449933
Belz GG and Aust PE [Threshold of action of meproscillarin following intravenous administration]. 1980 Med Klin pmid:7001203
Lindner E et al. [14,15-beta-oxido analog of proscillaridin (HOE 040). A new cardiac glycoside with low arrhythmic activity and greater absorption ratio]. 1979 Arzneimittelforschung pmid:109100
Beckmann H et al. [Meproscillarin in patients with renal failure and concomitant heart failure (author's transl)]. 1979 Med Klin pmid:522817
Tytman B [Construction of tables facilitating daily control of treatment with proscillaridin A]. 1979 Pol Tyg Lek pmid:575563
Bergdahl B Disposition rate of proscillaridin A in man after multiple oral doses. 1979 Arzneimittelforschung pmid:582147
Regal DS and Waginger H [Effect of proscillaridin on specific adenosine triphosphatases in heart muscle of rats. Electron optical demonstration and significance for calcium metabolism]. 1978 Zentralbl Veterinarmed A pmid:212903
Regal DS [Effect of proscillaridin on adenosine triphosphatase in kidney tissue in the rat. Electron microscopy demonstration and significance for calcium metabolism]. 1978 Zentralbl Veterinarmed A pmid:153691
Kubinyi H [Meproscillarin, a new semisynthetic cardiac glycoside/chemistry and physical properties (author's transl)]. 1978 Arzneimittelforschung pmid:580577
Friedrich L et al. [Studies on extracardiac effects of the cardiac glycoside meproscillarin in animal experiments (author's transl)]. 1978 Arzneimittelforschung pmid:580579
Andersson KE et al. Biliary excretion and enterochepatic recycling of proscillaridin A after oral adminstration to man. 1977 Eur. J. Clin. Pharmacol. pmid:862647
Andersson KE et al. Proscillaridin activity in portal and peripheral venous blood after oral administration to man. 1977 Eur. J. Clin. Pharmacol. pmid:862648
Bergdahl B and Andersson KE Stability in vitro of methylproscillaridin. 1977 Eur. J. Clin. Pharmacol. pmid:16755
Stauch M et al. [Effect of proscillaridin-4'-methylether on pressure rise velocity in the left ventricle of patients with coronary heart disease (author's transl)]. 1977 Klin. Wochenschr. pmid:330937
Stefan G [Echocardiography during the therapy of cardiovascular diseases]. 1977 MMW Munch Med Wochenschr pmid:401936
Wójcicki J and Stanosz S [Comparative studies of action in cats of intraintestinally administered digoxin, proscillardin and K- strophantoside]. 1977 Acta Pol Pharm pmid:930618
Garcia Casado P et al. Proscillaridin A yield from squill bulbs. 1977 Pharm Acta Helv pmid:565519
Andersson KE et al. On the absorption of proscillaridin A after single oral doses to normal and achlorhydric subjects. 1977 Acta Pharmacol Toxicol (Copenh) pmid:576356
Andersson KE et al. Activities of proscillaridin A in thoracic duct lymph after single oral doses in man. 1977 Acta Pharmacol Toxicol (Copenh) pmid:576557
Neugebauer G [Influence of high intravenous doses of D-penicillamine on toxic actions of cardiac glycosides in the guinea pig. Short communication (author's transl)]. 1977 Arzneimittelforschung pmid:580003
Belz GG et al. Pharmacokinetics and pharmacodynamics of methyl proscillaridin in healthy man. 1976 Eur. J. Clin. Pharmacol. pmid:786669
Einig H [Investigations on the Stability of Proscillaridine, Proscillaridine-3'-methylether and Proscillaridine-4'-methylether in Artificial Gastric and Intestinal Fluids (author's transl)]. 1976 Arzneimittelforschung pmid:12764
Belz GG et al. Plasma concentrations during repeated intravenous and oral methyl-proscillaridin application in man. 1976 Arzneimittelforschung pmid:947212
Krämer KD and Hochrein H [Enteral availability and therapeutic activity of proscillaridin-4'-methyl ether (author's transl)]. 1976 Arzneimittelforschung pmid:989015
Bellardo G and Pichierri U [Trial of a combination of proscillaridin A, thioridazine and Cori ester in the ambulatory treatment of some cardiopathies, especially senile types]. 1976 Minerva Med. pmid:967364
Stefan G [Echocardiographic evaluation of left ventricular function during therapy with cardiovascularly effective drugs]. 1976 Z Kardiol pmid:969820
Krämer KD and Hochrein H [Enteral availability and suggested dosages for methyl proscillaridin in decompensated heart patients]. 1975 Verh Dtsch Ges Inn Med pmid:1227053
Andersson KE et al. On the pharmacokinetics of proscillaridin A in man. 1975 Eur. J. Clin. Pharmacol. pmid:1233243
Rietbrock N and Staud R Metabolism and excretion of methylproscillaridin by man. 1975 Eur. J. Clin. Pharmacol. pmid:1233244
Staud R et al. Excretion of methylproscillaridin in patients with a biliary fistula. 1975 Eur. J. Clin. Pharmacol. pmid:1233271
Andersson KE et al. In vitro stability of proscillaridin A. 1975 Eur. J. Clin. Pharmacol. pmid:9294
Zalar S et al. [Relationship between binding to the myocardium and effects of proscillaridin on isolated perfused heart of the guinea pig]. 1975 Boll Chim Farm pmid:1131317
Nishida H et al. [Effect of proscillaridin on active cation transport across human red cell membrane (author's transl)]. 1974 Hokkaido Igaku Zasshi pmid:4477138
Nishida H [Studies on direct effects of proscillaridin A on the electrolyte excretion and transport ATPase in dog kidneys (author's transl)]. 1974 Hokkaido Igaku Zasshi pmid:4281758
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