2-hydroxyestradiol

2-hydroxyestradiol is a lipid of Sterol Lipids (ST) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1446 references associated with 2-hydroxyestradiol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 2-hydroxyestradiol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-hydroxyestradiol

MeSH term MeSH ID Detail
Kidney Neoplasms D007680 29 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Total 4

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-hydroxyestradiol

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Authors Title Published Journal PubMed Link
Higuchi A et al. Evaluation of treatment for dry eye with 2-hydroxyestradiol using a dry eye rat model. 2016 Mol. Vis. pmid:27186071
Schaufelberger SA et al. 2-Methoxyestradiol, an endogenous 17β-estradiol metabolite, inhibits microglial proliferation and activation via an estrogen receptor-independent mechanism. 2016 Am. J. Physiol. Endocrinol. Metab. pmid:26732685
Gao WL et al. Measurement of serum estrogen and estrogen metabolites in pre- and postmenopausal women with osteoarthritis using high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. 2015 Braz. J. Med. Biol. Res. pmid:25410577
Li HH et al. Estradiol 17β and its metabolites stimulate cell proliferation and antagonize ascorbic acid-suppressed cell proliferation in human ovarian cancer cells. 2014 Reprod Sci pmid:23757313
Savage KI et al. BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability. 2014 Cancer Res. pmid:24638981
Aitken RJ et al. On methods for the detection of reactive oxygen species generation by human spermatozoa: analysis of the cellular responses to catechol oestrogen, lipid aldehyde, menadione and arachidonic acid. 2013 Andrology pmid:23316012
Brosnan JF et al. Norethisterone acetate alters coagulation gene expression in vitro in human cell culture. 2013 Thromb. Res. pmid:22999413
Babbs RK et al. 2-Hydroxyestradiol enhances binge onset in female rats and reduces prefrontal cortical dopamine in male rats. 2013 Horm Behav pmid:23116652
Mosli HA et al. Catechol estrogens induce proliferation and malignant transformation in prostate epithelial cells. 2013 Toxicol. Lett. pmid:23685341
Sepkovic DW et al. 3,3'-Diindolylmethane increases serum interferon-γ levels in the K14-HPV16 transgenic mouse model for cervical cancer. 2012 Mar-Apr In Vivo pmid:22351660