16alpha-hydroxyestrone

16alpha-hydroxyestrone is a lipid of Sterol Lipids (ST) class. 16alpha-hydroxyestrone is associated with abnormalities such as Estrogenic effect. The involved functions are known as Cell Proliferation, Estrogen Metabolism, Polymorphism, Genetic and Protective Agents. The associated genes with 16alpha-hydroxyestrone are SHBG gene, Alleles and CYP17A1 gene. The related lipids are 16-ketoestradiol and 4-methoxyestradiol.

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Introduction

To understand associated biological information of 16alpha-hydroxyestrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 16alpha-hydroxyestrone?

16alpha-hydroxyestrone is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 16alpha-hydroxyestrone

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with 16alpha-hydroxyestrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 16alpha-hydroxyestrone?

There are no associated biomedical information in the current reference collection.

What functions are associated with 16alpha-hydroxyestrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 16alpha-hydroxyestrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 16alpha-hydroxyestrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 16alpha-hydroxyestrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 16alpha-hydroxyestrone

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Authors Title Published Journal PubMed Link
Sawicka E and Długosz A The role of 17β-estradiol metabolites in chromium-induced oxidative stress. 2017 Mar-Apr Adv Clin Exp Med pmid:28791837
Chen X et al. Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II-Associated Pulmonary Arterial Hypertension Through MicroRNA-29-Mediated Modulation of Cellular Metabolism. 2016 Circulation pmid:26487756
Gao WL et al. Measurement of serum estrogen and estrogen metabolites in pre- and postmenopausal women with osteoarthritis using high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. 2015 Braz. J. Med. Biol. Res. pmid:25410577
Dikshit A et al. Flaxseed reduces the pro-carcinogenic micro-environment in the ovaries of normal hens by altering the PG and oestrogen pathways in a dose-dependent manner. 2015 Br. J. Nutr. pmid:25850566
Samavat H and Kurzer MS Estrogen metabolism and breast cancer. 2015 Cancer Lett. pmid:24784887
Gheldiu AM et al. Oxidative Metabolism of Estrone Modified by Genistein and Bisphenol A in Rat Liver Microsomes. 2015 Biomed. Environ. Sci. pmid:26695363
Godínez Martínez EY et al. [Determination of 2-hydroxyestrone /16α-hydroxyestrone ratio in urine of Mexican women as a risk indicator for breast cancer and its relationship with other risk factors]. 2014 Nutr Hosp pmid:25617571
Bazzan AJ et al. Multi-nutrient supplement improves hormone ratio associated with cancer risk. 2013 J Transl Med pmid:24103703
Matthews CE et al. Association between physical activity and urinary estrogens and estrogen metabolites in premenopausal women. 2012 J. Clin. Endocrinol. Metab. pmid:22855335
White K et al. Activity of the estrogen-metabolizing enzyme cytochrome P450 1B1 influences the development of pulmonary arterial hypertension. 2012 Circulation pmid:22859684