MeSH term | MeSH ID | Detail |
---|---|---|
Kidney Failure, Chronic | D007676 | 51 associated lipids |
Hyperaldosteronism | D006929 | 4 associated lipids |
Aldosterone is a lipid of Sterol Lipids (ST) class. Aldosterone is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, endothelial dysfunction, Myocardial Infarction and Kidney Diseases. The involved functions are known as physiological aspects, Regulation, Gene Expression, Hypertrophy and Inflammation. Aldosterone often locates in Renal Tissue, Renin-Angiotensin-Aldosterone System, Body tissue, Protoplasm and Epithelium. The associated genes with Aldosterone are TSC22D3 gene, Candidate Disease Gene, SGK1 gene, Operator gene and ATP1A1 gene. The related lipids are Steroids. The related experimental models are Mouse Model.
To understand associated biological information of Aldosterone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Aldosterone is suspected in Hypertensive disease, Conn Syndrome, Cardiovascular Diseases, Hyperaldosteronism, endothelial dysfunction, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Aldosterone
MeSH term | MeSH ID | Detail |
---|---|---|
Kidney Failure, Chronic | D007676 | 51 associated lipids |
Hyperaldosteronism | D006929 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Cross talk between corticosteroids and alpha-adrenergic signalling augments cardiomyocyte hypertrophy: a possible role for SGK1.' (Lister K et al., 2006) and Mouse Model are used in the study 'Mineralocorticoid receptor agonists induce mouse aortic aneurysm formation and rupture in the presence of high salt.' (Liu S et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Lee S et al. | Fetal Exposure to Low Levels of the Plasticizer DEHP Predisposes the Adult Male Adrenal Gland to Endocrine Disruption. | 2017 | Endocrinology | pmid:27849367 |
Rasche FM et al. | Modern peptide biomarkers and echocardiography in cardiac healthy haemodialysis patients. | 2017 | BMC Nephrol | pmid:28558715 |
Senni M et al. | Biomarkers of Heart Failure with Preserved and Reduced Ejection Fraction. | 2017 | Handb Exp Pharmacol | pmid:28181009 |
Rieke S et al. | Mixture effects of azole fungicides on the adrenal gland in a broad dose range. | 2017 | Toxicology | pmid:28454766 |
Jones ES et al. | High Frequency of Variants of Candidate Genes in Black Africans with Low Renin-Resistant Hypertension. | 2017 | Am. J. Hypertens. | pmid:28052878 |
Werth S et al. | Obesity-stimulated aldosterone release is not related to an S1P-dependent mechanism. | 2017 | J. Endocrinol. | pmid:28970286 |
Graudal NA et al. | Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride. | 2017 | Cochrane Database Syst Rev | pmid:28391629 |
Sano Y et al. | Effects of various types of anesthesia on hemodynamics, cardiac function, and glucose and lipid metabolism in rats. | 2016 | Am. J. Physiol. Heart Circ. Physiol. | pmid:27694213 |
Guo H et al. | Endoplasmic Reticulum Chaperon Tauroursodeoxycholic Acid Attenuates Aldosterone-Infused Renal Injury. | 2016 | Mediators Inflamm. | pmid:27721575 |
Wen Y et al. | Correlation of baseline hormonal disorders with immunological failure and mortality in male HIV patients during follow-up. | 2016 | Medicine (Baltimore) | pmid:28033281 |