Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

Cross Reference

Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Arteriosclerosis D001161 86 associated lipids
Body Weight D001835 333 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

Download all related citations
Per page 10 20 50 100 | Total 3869
Authors Title Published Journal PubMed Link
Andersen PH and Packer JT Hepatic adenoma. Observations after estrogen withdrawal. 1976 Arch Surg pmid:182106
Boveris A and Stoppani AO Inhibition of mitochondrial swelling by 19-nor-ethynyltestosterone acetate and other steroids. 1971 Arch. Biochem. Biophys. pmid:4322804
Boveris A and Stoppani AO Inhibition of electron and energy transfer in mitochondria by 19-nor-ethynyltestosterone acetate. 1970 Arch. Biochem. Biophys. pmid:4322290
Nallani GC et al. Tissue-specific uptake and bioconcentration of the oral contraceptive norethindrone in two freshwater fishes. 2012 Arch. Environ. Contam. Toxicol. pmid:21710293
Stier G et al. [Experience in the treatment of metastatic breast carcinoma with norethisterone acetate in a clinical study]. 1989 Arch. Geschwulstforsch. pmid:2655553
Bohnet HG et al. Effects of synthetic gestagens on serum prolactin and growth hormone secretion in amenorrheic patients. 1978 Arch. Gynecol. pmid:736621
Breckwoldt M et al. Plasma levels of FSH and LH in patients with gonadal dysgenesis during sequential estrogen and progestogen therapy. 1980 Arch. Gynecol. pmid:6779717
Roll H et al. [Feedback--regulation mechanisms using a multiple graded mestranol-norethisterone sequential preparation in XO Turner's syndrome]. 1979 Arch. Gynecol. pmid:485482
Ferrero S and Remorgida V Endometriosis presenting with hemorrhagic ascites. 2011 Arch. Gynecol. Obstet. pmid:21153594
Yildirim G et al. Effects of two different regimens of continuous hormone replacement therapy on endometrial histopathology and postmenopausal uterine bleeding. 2006 Arch. Gynecol. Obstet. pmid:16315025
Tugrul S et al. Comparison of two forms of continuous combined hormone replacement therapy with respect to metabolic effects. 2007 Arch. Gynecol. Obstet. pmid:17051405
Petraglia F et al. Reduced pelvic pain in women with endometriosis: efficacy of long-term dienogest treatment. 2012 Arch. Gynecol. Obstet. pmid:21681516
Ferrero S et al. Changes in the size of rectovaginal endometriotic nodules infiltrating the rectum during hormonal therapies. 2013 Arch. Gynecol. Obstet. pmid:23053314
Cano A et al. The lipid and clinical effects of sequential transdermal estradiol and estradiol/norethisterone acetate in 674 women. 2003 Arch. Gynecol. Obstet. pmid:14504877
Bingol B et al. Effects of hormone replacement therapy on glucose and lipid profiles and on cardiovascular risk parameters in postmenopausal women. 2010 Arch. Gynecol. Obstet. pmid:19593578
Lindheimer MD et al. Oral-contraceptive-induced hypertension after adrenalectomy and hypophysectomy. 1976 Arch. Intern. Med. pmid:962446
DELORIMIER AA et al. METHYLTESTOSTERONE, RELATED STEROIDS, AND LIVER FUNCTION. 1965 Arch. Intern. Med. pmid:14315662
Wishart J et al. Treatment of postmenopausal hyperparathyroidism with norethindrone. Long-term effects on forearm mineral content. 1990 Arch. Intern. Med. pmid:2393326
Moses AM and Notman DD Secondary hyperparathyroidism caused by oral contraceptives. 1982 Arch. Intern. Med. pmid:6274264
Cole M Strokes in young women using oral contraceptives. 1967 Arch. Intern. Med. pmid:6054589
Horowitz M et al. Treatment of postmenopausal hyperparathyroidism with norethindrone. Effects on biochemistry and forearm mineral density. 1987 Arch. Intern. Med. pmid:3827457
Myrup B et al. Cardiovascular risk factors during estrogen-norethindrone and cholecalciferol treatment. 1992 Arch. Intern. Med. pmid:1332634
Macaraeg PV et al. Neutrophil alkaline phosphatase activity. Effect of certain oral contraceptive hormones. 1968 Arch. Intern. Med. pmid:4176910
Davidson MH et al. Effects of continuous estrogen and estrogen-progestin replacement regimens on cardiovascular risk markers in postmenopausal women. 2000 Arch. Intern. Med. pmid:11088095
Pasapera AM et al. In vitro molecular assessment of the mechanisms of action of 19-nor progestins used as contragestational agents. 1995 Arch. Med. Res. pmid:8845651
Oropeza MV et al. Estrogenic actions of norethisterone and its A-ring reduced metabolites. Induction of in vitro uterine sensitivity to serotonin. 1994 Arch. Med. Res. pmid:7803979
Altshuler JH et al. Neurological catastrophe related to oral contraceptives. 1968 Arch. Neurol. pmid:5725158
Gamboa ET et al. Chorea associated with oral contraceptive therapy. 1971 Arch. Neurol. pmid:5571013
Lai FM et al. Diffuse uterine leiomyomatosis with hemorrhage. 1991 Arch. Pathol. Lab. Med. pmid:1863197
Beliaeva LA et al. [Effect of progestins on the ultrastructure of endometrial cells in pretumorous changes and cancer (an organ-culture study)]. 1982 Arkh. Patol. pmid:7082195
Hemelaar M et al. Less effect of intranasal than oral hormone therapy on factors associated with venous thrombosis risk in healthy postmenopausal women. 2006 Arterioscler. Thromb. Vasc. Biol. pmid:16645152
Teede HJ et al. Postmenopausal hormone replacement therapy increases coagulation activity and fibrinolysis. 2000 Arterioscler. Thromb. Vasc. Biol. pmid:10807761
Barton M et al. Hormone replacement therapy and atherosclerosis in postmenopausal women: does aging limit therapeutic benefits? 2007 Arterioscler. Thromb. Vasc. Biol. pmid:17634518
Sherwood A et al. Age moderates the short-term effects of transdermal 17beta-estradiol on endothelium-dependent vascular function in postmenopausal women. 2007 Arterioscler. Thromb. Vasc. Biol. pmid:17541023
Taskinen MR et al. Hormone replacement therapy lowers plasma Lp(a) concentrations. Comparison of cyclic transdermal and continuous estrogen-progestin regimens. 1996 Arterioscler. Thromb. Vasc. Biol. pmid:8857916
Alexandersen P et al. Norethindrone acetate enhances the antiatherogenic effect of 17beta-estradiol: a secondary prevention study of aortic atherosclerosis in ovariectomized cholesterol-fed rabbits. 1998 Arterioscler. Thromb. Vasc. Biol. pmid:9633929
Bagdade JD and Subbaiah PV Atherosclerosis and oral contraceptive use. Serum from oral contraceptive users stimulates growth of arterial smooth muscle cells. 1982 Mar-Apr Arteriosclerosis pmid:7065983
Hansen A et al. Developments in lupus 2006. 2007 Arthritis Res. Ther. pmid:17634152
Høegh-Andersen P et al. Ovariectomized rats as a model of postmenopausal osteoarthritis: validation and application. 2004 Arthritis Res. Ther. pmid:15059281
Jungers P et al. Influence of oral contraceptive therapy on the activity of systemic lupus erythematosus. 1982 Arthritis Rheum. pmid:7092961
Hall GM et al. Markers of bone metabolism in postmenopausal women with rheumatoid arthritis. Effects of corticosteroids and hormone replacement therapy. 1995 Arthritis Rheum. pmid:7612039
Takenaka T et al. Judicious usage of estrogen/progesterone for angiodysplasia. 2005 Artif Organs pmid:15644090
Nishino Y and Neumann F [Estrogenic partial effect of gestagens, in particular that of norethisterone enanthate (author's transl)]. 1980 Arzneimittelforschung pmid:6770875
Gerhards E et al. Studies of the kinetics and metabolism of 17 beta-heptanoyl-17 alpha-ethinyl-4-oestren-3-one-7-3H (norethisterone enanthate) in humans following intramuscular injection. 1976 Arzneimittelforschung pmid:1036962
Warren RJ and Fotherby K Metabolism of D- and L-norgestrel in humans. 1975 Arzneimittelforschung pmid:169856
Kulcsár A et al. Hepatic actions of progestogenic steroids. 1984 Arzneimittelforschung pmid:6542791
Kulcsár A and Kulcsár-Gergely J Administration of progesterone and progestogens in chronical liver injury. 1979 Arzneimittelforschung pmid:156027
Kulcsár-Gergely J and Kulcsár A The sexual cycle in rats during progesterone and progestogen treatment. 1979 Arzneimittelforschung pmid:156028
Zeller WJ et al. Compatibility of hormonal contraceptives in diabetics. Results of a questionnaire survey. 1974 Arzneimittelforschung pmid:4135187
van der Vies J and de Visser J Endocrinological studies with desogestrel. 1983 Arzneimittelforschung pmid:6221730