Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

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Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

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Authors Title Published Journal PubMed Link
Xu B et al. Differential effects of progestogens, by type and regimen, on estrogen-metabolizing enzymes in human breast cancer cells. 2007 Maturitas pmid:16962266
Oosterbaan HP et al. The effects of continuous combined transdermal oestrogen-progestogen treatment on bleeding patterns and the endometrium in postmenopausal women. 1995 Maturitas pmid:7616870
Boon J et al. Continuous intrauterine compared with cyclic oral progestin administration in perimenopausal HRT. 2003 Maturitas pmid:12963171
Høvik P et al. Comparison of continuous and sequential oestrogen-progestogen treatment in women with climacteric symptoms. 1989 Maturitas pmid:2498620
Nordin BE et al. A placebo-controlled trial of ethinyl oestradiol and norethisterone in climacteric women. 1980 Maturitas pmid:7003315
Cornu C et al. Postmenopause hormone treatment in women with NIDDM or impaired glucose tolerance: the MEDIA randomized clinical trial. 2000 Maturitas pmid:11137328
Goudev A et al. Effects of low dose hormone replacement therapy on markers of inflammation in postmenopausal women. 2002 Maturitas pmid:12270582
Tatsumi H et al. Lack of stimulatory effect of dienogest on the expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 by endothelial cell as compared with other synthetic progestins. 2002 Maturitas pmid:12191851
Eiken P and Kolthoff N Compliance with long-term oral hormonal replacement therapy. 1995 Maturitas pmid:8538490
Mueck AO et al. Impact of hormone replacement therapy on endogenous estradiol metabolism in postmenopausal women. 2002 Maturitas pmid:12385856
Norris LA et al. Haemostatic risk factors in healthy postmenopausal women taking hormone replacement therapy. 2002 Maturitas pmid:12385861
Brynhildsen J and Hammar M Lipids and clotting factors during low dose transdermal estradiol/norethisterone use. 2005 Maturitas pmid:15780536
Li C et al. Effects of norethisterone acetate addition to estradiol in long term HRT. 2000 Maturitas pmid:11006501
Staland B Absorption of an oestrogen-progestogen preparation. 1983 Maturitas pmid:6633271
Nathorst-Böös J and Hammar M Effect on sexual life--a comparison between tibolone and a continuous estradiol-norethisterone acetate regimen. 1997 Maturitas pmid:9032742
Silfverstolpe G et al. Lipid metabolic studies in oophorectomised women: effects on serum lipids and lipoproteins of three synthetic progestogens. 1982 Maturitas pmid:6811837
Yilmazer M et al. Hormone replacement therapy, C-reactive protein, and fibrinogen in healthy postmenopausal women. 2003 Maturitas pmid:14625121
Haapasaari KM et al. Systemic therapy with estrogen or estrogen with progestin has no effect on skin collagen in postmenopausal women. 1997 Maturitas pmid:9255750
Alfie J et al. Hemodynamic effects of transdermal estradiol alone and combined with norethisterone acetate. 1997 Maturitas pmid:9255751
Ruan X et al. The pharmacology of dienogest. 2012 Maturitas pmid:22364708
Stadberg E et al. Bioavailability of norethisterone acetate alone and in combination with estradiol administered in single or multiple oral doses to postmenopausal women. 1999 Maturitas pmid:10585174
Christodoulakos G et al. Serum androgen levels and insulin resistance in postmenopausal women: association with hormone therapy, tibolone and raloxifene. 2005 Maturitas pmid:15780533
Lambrinoudaki IV et al. Circulating leptin and ghrelin are differentially influenced by estrogen/progestin therapy and raloxifene. 2008 Maturitas pmid:18164562
Gruber DM et al. Endometrial cancer after combined hormone replacement therapy. 1999 Maturitas pmid:10340283
Ranta V et al. National differences in lipid response to postmenopausal hormone replacement therapy. 2002 Maturitas pmid:12191848
Posaci C et al. The values of urinary NTx in postmenopausal women undergoing HRT; the role of additional alendronate therapy. 2002 Maturitas pmid:12191850
Loh FH et al. The efficacy of two dosages of a continuous combined hormone replacement regimen. 2002 Maturitas pmid:11836043
Staland B Continuous treatment with natural oestrogens and progestogens. A method to avoid endometrial stimulation. 1981 Maturitas pmid:7026979
Fernandes CE et al. Effects of estradiol and norethisterone on lipids, insulin resistance and carotid flow. 2008 Maturitas pmid:18359175
Odmark IS et al. Effects of continuous combined conjugated estrogen/medroxyprogesterone acetate and 17beta-estadiol/norethisterone acetate on lipids and lipoproteins. 2004 Maturitas pmid:15172088
Albertazzi P et al. The effect of tibolone versus continuous combined norethisterone acetate and oestradiol on memory, libido and mood of postmenopausal women: a pilot study. 2000 Maturitas pmid:11063905
Magos AL et al. Endometrial and menstrual response to subcutaneous oestradiol and testosterone implants and continuous oral progestogen therapy in post-menopausal women. 1985 Maturitas pmid:4079826
Kwok S et al. Effects of dydrogesterone and norethisterone, in combination with oestradiol, on lipoproteins and inflammatory markers in postmenopausal women. 2006 Maturitas pmid:16139447
Wiklund I et al. Long-term effect of transdermal hormonal therapy on aspects of quality of life in postmenopausal women. 1992 Maturitas pmid:1508062
Zhou J et al. Medroxyprogesterone acetate-driven increase in breast cancer risk might be mediated via cross-talk with growth factors in the presence of progesterone receptor membrane component-1. 2013 Maturitas pmid:23856385
Bassol S et al. The impact of a monophasic continuous estro-progestogenic treatment on Latin American menopausal women. 2005 Maturitas pmid:15734600
Oguz S et al. The role of hormone replacement therapy in endometrial polyp formation. 2005 Maturitas pmid:15734604
Junkermann H et al. Influence of different HRT regimens on mammographic density. 2005 Maturitas pmid:15653007
al-Azzawi F et al. Investigation of the bleeding patterns of postmenopausal women treated with Estrapak-50. 1994 Maturitas pmid:8177092
Posaci C et al. Effects of HRT on serum levels of IGF-I in postmenopausal women. 2001 Maturitas pmid:11684375
Eilertsen AL et al. Conventional-dose hormone therapy (HT) and tibolone, but not low-dose HT and raloxifene, increase markers of activated coagulation. 2006 Maturitas pmid:16713143
Paterson ME A randomised, double-blind, cross-over study into the effect of sequential mestranol and norethisterone on climacteric symptoms and biochemical parameters. 1982 Maturitas pmid:6750325
Lindgren R et al. Endometrial effects of transdermal estradiol/norethisterone acetate. 1992 Maturitas pmid:1528133
Gambacciani M et al. Ultra low-dose hormone replacement therapy and bone protection in postmenopausal women. 2008 Maturitas pmid:18063490
Taner MZ et al. Effects of four different regimens of hormone replacement therapy on hemostatic parameters: a prospective randomized study. 2006 Maturitas pmid:15978753
Mattsson LA et al. Evaluation of a continuous oestrogen-progestogen regimen for climacteric complaints. 1982 Maturitas pmid:7121296
Jondet M and Dehennin L Impact of different progestins on endometrial vascularisation of postmenopausal women. A retrospective image analysis-morphometric study. 2003 Maturitas pmid:14585519
Pata O et al. The effects of hormone replacement therapy type on pulmonary functions in postmenopausal women. 2003 Maturitas pmid:14585524
Christodoulakos GE et al. The effect of various regimens of hormone replacement therapy on mammographic breast density. 2003 Maturitas pmid:12787969
Fotherby K Pharmacokinetics of progestational compounds. 1986 Maturitas pmid:2943973