Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

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Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

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Authors Title Published Journal PubMed Link
Gusenleitner D et al. Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action. 2014 PLoS ONE pmid:25058030
Huang R et al. Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway. 2014 Sci Rep pmid:25012808
Ralph L et al. Research on hormonal contraception and HIV - Authors' reply. 2014 Lancet pmid:24461119
Basavaraja N et al. Norethindrone-induced masculinization and progeny testing in guppy, Poecilia reticulata (Peters 1859). 2014 Indian J. Exp. Biol. pmid:24669666
Santos M et al. Retrospective review of norethindrone use in adolescents. 2014 J Pediatr Adolesc Gynecol pmid:24315714
Ferrero S et al. Norethisterone acetate versus norethisterone acetate combined with letrozole for the treatment of ovarian endometriotic cysts: a patient preference study. 2014 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:24388845
Zomerdijk IM et al. Dispensing of potentially teratogenic drugs before conception and during pregnancy: a population-based study. 2015 BJOG pmid:25316196
Atrio J et al. The effect of protease inhibitors on the cervical mucus of HIV-positive women taking norethindrone contraception. 2015 Eur J Contracept Reprod Health Care pmid:25285572
DuBois BN et al. Increased exposure of norethindrone in HIV+ women treated with ritonavir-boosted atazanavir therapy. 2015 Contraception pmid:25245190
Posadzy-Malaczynska A et al. Hemodynamic and metabolic effects of estrogen plus progestin therapy in hypertensive postmenopausal women treated with an ACE-inhibitor or a diuretic. 2015 Clin Res Cardiol pmid:25216597