Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

Cross Reference

Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Arteriosclerosis D001161 86 associated lipids
Body Weight D001835 333 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

Download all related citations
Per page 10 20 50 100 | Total 3869
Authors Title Published Journal PubMed Link
Rowan JP "Estrophasic" dosing: A new concept in oral contraceptive therapy. 1999 Am. J. Obstet. Gynecol. pmid:9988834
Mills TM et al. Metabolism of oral contraceptive drugs. The formation and disappearance of metabolites of norethindrone and mestranol after intravenous and oral administration. 1976 Am. J. Obstet. Gynecol. pmid:998688
Al-Azzawi F et al. Continuous combined hormone replacement therapy compared with tibolone. 1999 Obstet Gynecol pmid:9932566
Ohman L et al. Topical administration of progestational steroids in the eye and nose--a rapid absorption to the blood. 1978 Contraception pmid:99284
Weiner E and Johansson ED The influence of norethisterone oenanthate on ovarian function. 1976 Acta Endocrinol. pmid:989667
Rowlands SC and Dakin L Twelve years of injectable contraceptive use in a general practice. 1998 Br J Fam Plann pmid:9882767
Briatico G et al. Effects of contraceptive agents on drug metabolism in various animal species. 1976 Br. J. Pharmacol. pmid:987822
Raudaskoski T et al. Plasma insulin-like growth factor-I and its binding proteins 1 and 3 during continuous nonoral and oral combined hormone replacement therapy. 1998 Menopause pmid:9872487
Trapnell CB et al. Thalidomide does not alter the pharmacokinetics of ethinyl estradiol and norethindrone. 1998 Clin. Pharmacol. Ther. pmid:9871424
Ladinsky H et al. Lack of influence of the phase of estrus cycle or treatment with steroid contraceptive drugs on cholinergic parameters in mouse and rat brain. 1976 Pharmacology pmid:986656
Darj E et al. Ultrasonographic blood flow measurement in the carotid arteries in postmenopausal women. 1999 Gynecol. Obstet. Invest. pmid:9852387
Hägglund H et al. Norethisterone treatment, a major risk-factor for veno-occlusive disease in the liver after allogeneic bone marrow transplantation. 1998 Blood pmid:9845522
Yadava HS et al. Effect of low dose norethindrone acetate released through subdermal silastic implant on lipid metabolism in female rhesus monkeys. 1978 Indian J. Exp. Biol. pmid:98430
Lamble JW and Lamble AP Some effects of progestogens, oestrogens and androgens on the ocular tension of rabbits and owl monkeys. 1978 Exp. Eye Res. pmid:98336
LeBel M et al. Effects of rifabutin and rifampicin on the pharmacokinetics of ethinylestradiol and norethindrone. 1998 J Clin Pharmacol pmid:9824786
Sturdee DW et al. Glucose tolerance and hormone replacement therapy. A preliminary study. 1976 Postgrad Med J pmid:981120
Burnett D et al. Plasma protein changes in post-menopausal women receiving mestranol-norethisterone hormone replacement therapy. 1976 Postgrad Med J pmid:981119
Moore B Sequential mestranol and morethisterone in the treatment of the climacteric syndrome. 1976 Postgrad Med J pmid:981118
Verhoeven CH et al. In vitro and in vivo metabolism of the progestagen Org 30659 in several species. 1998 Drug Metab. Dispos. pmid:9806953
Berg G et al. Effect of oral contraceptive progestins on serum copper concentration. 1998 Eur J Clin Nutr pmid:9805216
Martelli A et al. Induction of micronuclei and of enzyme-altered foci in the liver of female rats exposed to progesterone and three synthetic progestins. 1998 Mutat. Res. pmid:9804880
Lachnit-Fixson U and Aydinlik S [New cycle-stabilizing contraceptive agent (Ediwal)]. 1976 Med Monatsschr pmid:979900
Rogers A and Eastell R Effects of estrogen therapy of postmenopausal women on cytokines measured in peripheral blood. 1998 J. Bone Miner. Res. pmid:9783546
Cacciatore B et al. Randomized comparison of oral and transdermal hormone replacement on carotid and uterine artery resistance to blood flow. 1998 Obstet Gynecol pmid:9764629
Funckes CG et al. Effect of a long-acting contraceptive drug, norethindrone enanthate, on serum zinc and copper in human volunteers. 1976 Contraception pmid:975819
Fotherby K and Warren RJ Bioavailability of contraceptive steroids from capsules. 1976 Contraception pmid:975817
Sturdee DW et al. Pregnancy associated alpha2-glycoprotein in post-menopausal women receiving hormone replacement therapy. 1976 Clin. Chim. Acta pmid:975579
Tant D Megaloblastic anaemia due to pyridoxine deficiency associated with prolonged ingestion of an oestrogen-containing oral contraceptive. 1976 Br Med J pmid:974714
Gal I Hormonal pregnancy tests and congenital malformations. 1976 Br Med J pmid:974708
Hammar M et al. A double-blind, randomised trial comparing the effects of tibolone and continuous combined hormone replacement therapy in postmenopausal women with menopausal symptoms. 1998 Br J Obstet Gynaecol pmid:9746385
Kaba S et al. Endometrial cytology in postmenopausal hormone replacement therapy. 1998 Diagn. Cytopathol. pmid:9740987
Barkin JS and Ross BS Medical therapy for chronic gastrointestinal bleeding of obscure origin. 1998 Am. J. Gastroenterol. pmid:9707046
Moyer DL and Felix JC The effects of progesterone and progestins on endometrial proliferation. 1998 Contraception pmid:9693400
Bech P et al. Combined versus sequential hormonal replacement therapy: a double-blind, placebo-controlled study on quality of life-related outcome measures. 1998 Jul-Oct Psychother Psychosom pmid:9693354
Picazo O et al. A-ring reduced derivatives of two synthetic progestins induce anxiolytic effects in ovariectomized rats. 1998 Brain Res. pmid:9689453
Arteaga E et al. In vitro effect of estradiol, progesterone, testosterone, and of combined estradiol/progestins on low density lipoprotein (LDL) oxidation in postmenopausal women. 1998 Menopause pmid:9689190
Ostad SN et al. In vitro cytotoxicity and teratogenicity of norethisterone and levonorgestrel released from hollow nylon monofilaments. 1998 J Control Release pmid:9685884
Powles TJ et al. The effects of norethisterone on endometrial abnormalities identified by transvaginal ultrasound screening of healthy post-menopausal women on tamoxifen or placebo. 1998 Br. J. Cancer pmid:9683306
Anzaldua SR et al. Differential effects of 5 alpha-norethisterone on the histomorphology of the oviduct and uterus of the pregnant rabbit. 1998 Contraception pmid:9673843
Irvine GA et al. Randomised comparative trial of the levonorgestrel intrauterine system and norethisterone for treatment of idiopathic menorrhagia. 1998 Br J Obstet Gynaecol pmid:9647148
Duckitt K and Shaw RW Is medical management of menorrhagia obsolete? 1998 Br J Obstet Gynaecol pmid:9647144
Stadberg E Research in progress. 1998 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:9643395
Liskowski L et al. The determination of progesterone receptors in breast cancer and their relationship to estrogen receptors. 1976 Clin. Chim. Acta pmid:963895
Alexandersen P et al. Norethindrone acetate enhances the antiatherogenic effect of 17beta-estradiol: a secondary prevention study of aortic atherosclerosis in ovariectomized cholesterol-fed rabbits. 1998 Arterioscler. Thromb. Vasc. Biol. pmid:9633929
Surrey ES Add-back therapy: extending safety and efficacy of GnRH analogues in the gynecologic patient. 1998 Gynecol. Obstet. Invest. pmid:9628522
Lindheimer MD et al. Oral-contraceptive-induced hypertension after adrenalectomy and hypophysectomy. 1976 Arch. Intern. Med. pmid:962446
Lei KY et al. Oral contraceptives, norethindrone and mestranol: effects on tissue levels of minerals. 1976 Am. J. Physiol. pmid:961877
Coutinho EM et al. The response of the human Fallopian tube to ergonovine and methyl-ergonovine in vivo. 1976 Am. J. Obstet. Gynecol. pmid:961746
Zeng X and Yao Z Experimental study on relationship between exogenous estrogen and breast cancer risk. 1997 Chin. Med. J. pmid:9594309
Ylikorkala O et al. The long-term effects of oral and transdermal postmenopausal hormone replacement therapy on nitric oxide, endothelin-1, prostacyclin, and thromboxane. 1998 Fertil. Steril. pmid:9591497