Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

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Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Arteriosclerosis D001161 86 associated lipids
Body Weight D001835 333 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

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Authors Title Published Journal PubMed Link
Koskela-Niska V et al. Ovarian cancer risk in postmenopausal women using estradiol-progestin therapy - a nationwide study. 2013 Climacteric pmid:22640598
Brosnan JF et al. Norethisterone acetate alters coagulation gene expression in vitro in human cell culture. 2013 Thromb. Res. pmid:22999413
Gutsche JT et al. Treatment of ventricular assist-device-associated gastrointestinal bleeding with hormonal therapy. 2013 J. Cardiothorac. Vasc. Anesth. pmid:24054188
Tomasicchio M et al. The progestin-only contraceptive medroxyprogesterone acetate, but not norethisterone acetate, enhances HIV-1 Vpr-mediated apoptosis in human CD4+ T cells through the glucocorticoid receptor. 2013 PLoS ONE pmid:23658782
Polisseni AF et al. Effects of a continuous-combined regimen of low-dose hormone therapy (oestradiol and norethindrone acetate) and tibolone on the quality of life in symptomatic postmenopausal women: a double-blind, randomised study. 2013 Maturitas pmid:23201326
Schneck H et al. Membrane-receptor initiated proliferative effects of dienogest in human breast cancer cells. 2013 Gynecol. Endocrinol. pmid:23116217
Połać I et al. Coagulation and fibrynolitic parameters in women and the effects of hormone therapy; comparison of transdermal and oral administration. 2013 Gynecol. Endocrinol. pmid:23116237
Chen FP et al. Effects of estradiol and progestogens on human breast cells: regulation of sex steroid receptors. 2013 Taiwan J Obstet Gynecol pmid:24075375
Minami T et al. Antiproliferative and apoptotic effects of norethisterone on endometriotic stromal cells in vitro. 2013 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:22964137
Crean CS et al. The effect of ezogabine on the pharmacokinetics of an oral contraceptive agent. 2013 Int J Clin Pharmacol Ther pmid:24040852
Demeestere I et al. Gonadotropin-releasing hormone agonist for the prevention of chemotherapy-induced ovarian failure in patients with lymphoma: 1-year follow-up of a prospective randomized trial. 2013 J. Clin. Oncol. pmid:23129737
Buccellato E et al. Possible occurrence of paraesthesia in patients taking norethisterone: an analysis on the WHO Global Individual Case Reports database (VigiBase). 2013 Expert Opin Drug Saf pmid:23701188
Manassiev N et al. Effects of tibolone or continuous combined oestradiol/norethisterone acetate on glucose and insulin metabolism. 2013 Clin. Endocrinol. (Oxf) pmid:22775481
Merviel P et al. [Interest of selective progesterone receptor modulators in endometriosis]. 2013 Gynecol Obstet Fertil pmid:23972920
Abdul-Hadi RA et al. The effectiveness of community based distribution of injectable contraceptives using community health extension workers in Gombe State, Northern Nigeria. 2013 Afr J Reprod Health pmid:24069754
Polis CB and Curtis KM Use of hormonal contraceptives and HIV acquisition in women: a systematic review of the epidemiological evidence. 2013 Lancet Infect Dis pmid:23871397
Biddle ST et al. Metabolism of norethisterone in the greyhound. 2013 Rapid Commun. Mass Spectrom. pmid:24019188
Ferrero S et al. Changes in the size of rectovaginal endometriotic nodules infiltrating the rectum during hormonal therapies. 2013 Arch. Gynecol. Obstet. pmid:23053314
LoRusso PM et al. Co-administration of vismodegib with rosiglitazone or combined oral contraceptive in patients with locally advanced or metastatic solid tumors: a pharmacokinetic assessment of drug-drug interaction potential. 2013 Cancer Chemother. Pharmacol. pmid:23064958
Jonusiene G et al. Sexual function, mood and menopause symptoms in Lithuanian postmenopausal women. 2013 Climacteric pmid:22845491