Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

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Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

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Authors Title Published Journal PubMed Link
Niv Y and Henkin Y Estrogen-progestin therapy and coronary heart disease in radiation-induced rectal telangiectases. 1995 J. Clin. Gastroenterol. pmid:8583103
Tamaya T et al. Contribution of functional groups of 19-nor-progestogens to binding to progesterone and estradiol-17beta receptors in rabbit uterus. 1977 Endocrinology pmid:858280
Ambrus JL et al. Progestational agents and blood coagulation. VIII. Effect of low-dose, alternate-day, estrogen-progestin combinations on blood coagulation factors in man, with a special note on the effect of freezing of blood samples. 1977 Am. J. Obstet. Gynecol. pmid:857675
Wibbels T and Crews D Steroid-induced sex determination at incubation temperatures producing mixed sex ratios in a turtle with TSD. 1995 Gen. Comp. Endocrinol. pmid:8575659
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Löw O et al. Morphometric investigations on endocrine glands. V. Changes in the testes of Wistar rats after application of chlormadinone acetate and norethisterone acetate. 1979 Exp Pathol (Jena) pmid:85556
Gunston KD Norethisterone enantate in the treatment of premenstrual syndrome. 1995 S. Afr. Med. J. pmid:8545742
Schoonen WG et al. Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines. 1995 J. Steroid Biochem. Mol. Biol. pmid:8541241
Schoonen WG et al. Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: I. MCF-7 cell lines. 1995 J. Steroid Biochem. Mol. Biol. pmid:8541240
Eiken P and Kolthoff N Compliance with long-term oral hormonal replacement therapy. 1995 Maturitas pmid:8538490
Braselton WE et al. Identification and measurement by gas chromatography-mass spectrometry of norethindrone and metabolites in human urine and blood. 1977 J. Steroid Biochem. pmid:853745
Moutos D et al. The effect of monophasic combinations of ethinyl estradiol and norethindrone on gonadotropins, androgens and sex hormone binding globulin: a randomized trial. 1995 Contraception pmid:8536446
Heiner JS et al. Comparison of a gonadotropin-releasing hormone agonist and a low dose oral contraceptive given alone or together in the treatment of hirsutism. 1995 J. Clin. Endocrinol. Metab. pmid:8530574
Wemme H et al. Effect of oestrogen/gestagen replacement therapy on liver enzymes in patients with Ullrich-Turner syndrome. 1995 Eur. J. Pediatr. pmid:8529677
Combs DW et al. Nonsteroidal progesterone receptor ligands. 2. High-affinity ligands with selectivity for bone cell progesterone receptors. 1995 J. Med. Chem. pmid:8523400
Broome M et al. Enlarged follicles in women using oral contraceptives. 1995 Contraception pmid:8521709
Taitel HF and Kafrissen ME Norethindrone--a review of therapeutic applications. 1995 Jul-Aug Int J Fertil Menopausal Stud pmid:8520623
Köse K et al. Contraceptive steroids increase erythrocyte lipid peroxidation in female rats. 1993 Contraception pmid:8508671
Nichols M et al. Effect of four combined oral contraceptives on blood pressure in the pill-free interval. 1993 Contraception pmid:8508666