Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

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Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

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Authors Title Published Journal PubMed Link
Bostofte E et al. Serum lipids and lipoproteins during treatment with oral contraceptives containing natural and synthetic oestrogens. A controlled double-blind investigation. 1978 Acta Endocrinol. pmid:347855
Varma SK and Bloch E Effects of prenatal administration of mestranol and two progestins on testosterone synthesis and reproductive tract development in male rats. 1987 Acta Endocrinol. pmid:2958983
Jelínek J et al. Effect of two progestins on human endometrial enzymes and trace elements. 1978 Acta Endocrinol. pmid:581024
Weiner E and Johansson ED The influence of norethisterone oenanthate on ovarian function. 1976 Acta Endocrinol. pmid:989667
KRAAY RJ and BRENNAN DM Evaluation of chlormadinone acetate and other progestogens for foetal masculinization in rats. 1963 Acta Endocrinol. pmid:14035354
Mauvais-Jarvis P et al. [In vivo studies on metabolism of androgens following administration of steroid inhibitors of ovulation. 1. Changes in the secretion of androgens and excretion of their metabolites in normal subjects and women with the Stein-Leventhal syndrome]. 1965 Acta Endocrinol. pmid:5897059
Larsson-Cohn U et al. Effects of continuous daily administration of 0.5 mg of norethindrone on the plasma levels of progesterone and on the urinary excretion of luteinizing hormone, pregnanediol and total oestrogens. 1970 Acta Endocrinol. pmid:5468622
Carlborg L et al. Effect of norethisterone acetate with or without ethinyl oestradiol on the sialic acid concentration and sperm receptivity of the cervical mucus. 1968 Acta Endocrinol. pmid:5757032
Plate WP Ovarian changes after long-term oral contraception. 1967 Acta Endocrinol. pmid:6071598
Murugesan K et al. In vitro metabolism of 6,7-3H) norethynodrel in the human endometrium and the myometrium. 1973 Acta Endocrinol. pmid:4800856
Loraine JA et al. Hormone excretion patterns during and ater the long-term administration of oral contraceptives. 1965 Acta Endocrinol. pmid:5897062
Odlind V and Johansson ED Free norethisterone as reflected by saliva concentrations of norethisterone during oral contraceptive use. 1981 Acta Endocrinol. pmid:7197450
Hagen C et al. Long-term effects of oestrogens in combination with gestagen on plasma prolactin and FSH levels in post-menopausal women. 1982 Acta Endocrinol. pmid:6812338
Hoppen HO and Hammann P The influence of structural modification on progesterone and androgen receptor binding of norethisterone. Correlation with nuclear magnetic resonance signals. 1987 Acta Endocrinol. pmid:3618086
Martínez-Manautou J et al. The ultrastructure of liver cells in women under steroid therapy. II. Contraceptive therapy. 1970 Acta Endocrinol. pmid:4097029
Larsson-Cohn U et al. Effects of continuous daily administration of 0.3 mg of norehtindrone on the plasma levels of progesterone and on the urinary excretion of pregnanediol and total oestrogens. 1970 Acta Endocrinol. pmid:4195422
Nuttal ID and Elstein M Steroid releasing vaginal rings. 1980 Acta Eur. Fertil. pmid:6781195
Beck LR and Cowsar D Biodegradable microsphere contraceptive system. 1980 Acta Eur. Fertil. pmid:7211111
De Cecco L et al. Effectiveness of norethisterone enantate in the treatment of the climacteic syndrome. 1982 Acta Eur. Fertil. pmid:7186258
Kesserü-Koós E et al. Fertility control with norethindrone enanthate, a long-acting parenteral progestogen. 1973 Acta Eur. Fertil. pmid:4802108