Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

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Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

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Authors Title Published Journal PubMed Link
Seeger H et al. Effect of medroxyprogesterone acetate and norethisterone on serum-stimulated and estradiol-inhibited proliferation of human coronary artery smooth muscle cells. 2001 Jan-Feb Menopause pmid:11201515
Walker RJ et al. The effects of sequential combined oral 17beta-estradiol norethisterone acetate on insulin sensitivity and body composition in healthy postmenopausal women: a randomized single blind placebo-controlled study. 2001 Jan-Feb Menopause pmid:11201511
Margen S and King JC Effect of oral contraceptive agents on the metabolism of some trace minerals. 1975 Am. J. Clin. Nutr. pmid:1119435
Prasad AS et al. Effect of oral contraceptive agents on nutrients: I. Minerals. 1975 Am. J. Clin. Nutr. pmid:1119434
Sørensen MB et al. Temporal changes in cardiac function and cerebral blood flow during sequential postmenopausal hormone replacement. 2001 Am. J. Obstet. Gynecol. pmid:11174477
Cardim HJ et al. The insulin-like growth factor-I system and hormone replacement therapy. 2001 Fertil. Steril. pmid:11172828
Teede HJ et al. Effects of oral combined hormone replacement therapy on platelet aggregation in postmenopausal women. 2001 Clin. Sci. pmid:11171290
McGuire JL et al. Effects of low dose oral contraceptives containing norethindrome and ethinyl estradiol on serum levels of progesterone and pituitary gonadotropins. 1975 Contraception pmid:1116369
Bai J et al. Regulation of invasive cell behavior by taiman, a Drosophila protein related to AIB1, a steroid receptor coactivator amplified in breast cancer. 2000 Cell pmid:11163181
Schoonen WG et al. Hormonal properties of norethisterone, 7alpha-methyl-norethisterone and their derivatives. 2000 J. Steroid Biochem. Mol. Biol. pmid:11162927
Gravholt CH et al. Reduced free IGF-I and increased IGFBP-3 proteolysis in Turner syndrome: modulation by female sex steroids. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11158935
Alexandersen P et al. Efficacy of levormeloxifene in the prevention of postmenopausal bone loss and on the lipid profile compared to low dose hormone replacement therapy. 2001 J. Clin. Endocrinol. Metab. pmid:11158042
Doyle LL Hormone-releasing silicone-rubber intrauterine contraceptive devices. Effect of incorporation of various compounds on intrauterine contraceptive devices in rats. 1975 Am. J. Obstet. Gynecol. pmid:1115155
Plumb JM and Guest JF Economic impact of tibolone compared with continuous-combined hormone replacement therapy. In the management of postmenopausal women with climacteric symptoms in the UK. 2000 Pharmacoeconomics pmid:11151401
Chihal HJ et al. Estrogen potency of oral contraceptive pills. 1975 Am. J. Obstet. Gynecol. pmid:1115120
Cornu C et al. Postmenopause hormone treatment in women with NIDDM or impaired glucose tolerance: the MEDIA randomized clinical trial. 2000 Maturitas pmid:11137328
Shojania AM et al. The effect of oral contraceptives on folate metabolism. III. Plasma clearance and urinary folate excretion. 1975 J. Lab. Clin. Med. pmid:1113011
Speroff L et al. The effect of varying low-dose combinations of norethindrone acetate and ethinyl estradiol (femhrt) on the frequency and intensity of vasomotor symptoms. 2000 Nov-Dec Menopause pmid:11127760
Briggs MH and Briggs M Thiamine status and oral contraceptives. 1975 Contraception pmid:1112084
Björn I et al. Negative mood changes during hormone replacement therapy: a comparison between two progestogens. 2000 Am. J. Obstet. Gynecol. pmid:11120505