Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

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Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

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Authors Title Published Journal PubMed Link
Eviö S et al. Failure of the combination of sequential oral and transdermal estradiol plus norethisterone acetate to affect plasma homocysteine levels. 2000 Fertil. Steril. pmid:11119731
Perry W and Wiseman RA Combined oral oestradiol valerate-norethisterone treatment over three years in postmenopausal women: correlation between oestrogen levels and bone mineral density sites. 2000 BJOG pmid:11117769
Sturdee DW et al. The endometrial response to sequential and continuous combined oestrogen-progestogen replacement therapy. 2000 BJOG pmid:11117768
Gao J et al. Ligand-activated progesterone receptor isoform hPR-A is a stronger transactivator than hPR-B for the expression of IGFBP-1 (insulin-like growth factor binding protein-1) in human endometrial stromal cells. 2000 Mol. Endocrinol. pmid:11117526
Davidson MH et al. Effects of continuous estrogen and estrogen-progestin replacement regimens on cardiovascular risk markers in postmenopausal women. 2000 Arch. Intern. Med. pmid:11088095
Deckers GH et al. Influence of the substitution of 11-methylene, delta(15), and/or 18-methyl groups in norethisterone on receptor binding, transactivation assays and biological activities in animals. 2000 J. Steroid Biochem. Mol. Biol. pmid:11086227
Irani S et al. Pleuroperitoneal endometriosis. 1976 Obstet Gynecol pmid:1107910
Fábián G et al. An unusual multiplex cause of severe gastrointestinal bleeding in a haemodialysed patient. 2000 Nephrol. Dial. Transplant. pmid:11071980
Seeger H et al. Effect of norethisterone acetate on estrogen metabolism in postmenopausal women. 2000 Horm. Metab. Res. pmid:11069210
Albertazzi P et al. The effect of tibolone versus continuous combined norethisterone acetate and oestradiol on memory, libido and mood of postmenopausal women: a pilot study. 2000 Maturitas pmid:11063905
Pierce SJ et al. Long-term use of gonadotropin-releasing hormone analogs and hormone replacement therapy in the management of endometriosis: a randomized trial with a 6-year follow-up. 2000 Fertil. Steril. pmid:11056241
Hümpel M et al. A new principle of injectable depot contraceptives. I Drug selection and studies in monkeys. 1979 Contraception pmid:110513
Dórea JG Oral contraceptives do not affect magnesium in breast milk. 2000 Int J Gynaecol Obstet pmid:11044538
Wonodirekso S et al. Endometrial epithelial integrity and subepithelial reticular fibre expression in progestin contraceptive acceptors. 2000 Hum. Reprod. pmid:11041235
Lethaby A et al. Antifibrinolytics for heavy menstrual bleeding. 2000 Cochrane Database Syst Rev pmid:11034679
Li C et al. Effects of norethisterone acetate addition to estradiol in long term HRT. 2000 Maturitas pmid:11006501
Amaro R and Barkin JS Diagnostic and therapeutic options in obscure gastrointestinal blood loss. 2000 Curr Gastroenterol Rep pmid:10998667
Heald A et al. Progestins abrogate estrogen-induced changes in the insulin-like growth factor axis. 2000 Am. J. Obstet. Gynecol. pmid:10992179
Dören M et al. Resistance of pelvic arteries and plasma lipids in postmenopausal women: comparative study of tibolone and continuous combined estradiol and norethindrone acetate replacement therapy. 2000 Am. J. Obstet. Gynecol. pmid:10992176
Kamischke A et al. Potential of norethisterone enanthate for male contraception: pharmacokinetics and suppression of pituitary and gonadal function. 2000 Clin. Endocrinol. (Oxf) pmid:10971453