Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

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Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

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Authors Title Published Journal PubMed Link
Kurman RJ et al. Norethindrone acetate and estradiol-induced endometrial hyperplasia. 2000 Obstet Gynecol pmid:10960628
Symons J et al. Vaginal bleeding in postmenopausal women taking low-dose norethindrone acetate and ethinyl estradiol combinations. The FemHRT Study Investigators. 2000 Obstet Gynecol pmid:10960627
Flodgaard D et al. Two oral contraceptives with the same gestagen and different estrogen. A controlled clinical trial. 1975 Contraception pmid:1095298
Grant C et al. Management of menorrhagia in primary care-impact on referral and hysterectomy: data from the Somerset Morbidity Project. 2000 J Epidemiol Community Health pmid:10942454
Chaudhury RR Modern trends in contraceptive pharmacology. 1975 J Med Assoc Thai pmid:1094081
Garza-Flores J and Stafford JE Solid-phase radioimmunoassay for norethisterone. 1979 Clin. Chim. Acta pmid:109237
Dexeus S and Fernández-Cid A [Cytological changes produced by anovulatories and intrauterine devices]. 1975 Acta Ginecol (Madr) pmid:1092123
Kovacs GT et al. A pre-coital pill? A preliminary in vitro study. 2000 Br J Fam Plann pmid:10920297
von Kesserü E et al. Premenopause contraception with monthly injectable Mesigyna with special emphasis on serum lipid and bone density patterns. 2000 Contraception pmid:10906502
Bassol S et al. Mesigyna once-a-month combined injectable contraceptive: experience in Latin America. 2000 Contraception pmid:10906501
Kaunitz AM Efficacy, cycle control, and safety of two triphasic oral contraceptives: Cyclessa (desogestrel/ethinyl estradiol) and ortho-Novum 7/7/7 (norethindrone/ethinyl estradiol): a randomized clinical trial. 2000 Contraception pmid:10906499
Winkler UH et al. Effects of tibolone and continuous combined hormone replacement therapy on parameters in the clotting cascade: a multicenter, double-blind, randomized study. 2000 Fertil. Steril. pmid:10899490
Wentz AC et al. Gonadotropin responses following luteinizing hormone releasing hormone administration in normal subjects. 1975 Obstet Gynecol pmid:1089927
Hamilton W Is norethisterone a lifestyle drug? The term lifestyle is not as clear as it may seem. 2000 BMJ pmid:10896443
Lloyd D Is norethisterone a lifestyle drug? It's not a lifestyle drug in North Harrow. 2000 BMJ pmid:10896442
Bryant G et al. Is norethisterone a lifestyle drug? Health is not merely the absence of disease. 2000 BMJ pmid:10896441
Halleen JM et al. Tartrate-resistant acid phosphatase 5b: a novel serum marker of bone resorption. 2000 J. Bone Miner. Res. pmid:10893682
Gonzalo-Lumbreras R and Izquierdo-Hornillos R High-performance liquid chromatographic optimization study for the separation of natural and synthetic anabolic steroids. Application to urine and pharmaceutical samples. 2000 J. Chromatogr. B Biomed. Sci. Appl. pmid:10892579
Spencer CP et al. Effects of oral and transdermal 17beta-estradiol with cyclical oral norethindrone acetate on insulin sensitivity, secretion, and elimination in postmenopausal women. 2000 Metab. Clin. Exp. pmid:10877199
Ravinder P et al. Biological efficacy and plasma norethisterone levels of orally administered norethisterone enanthate in rat and hamster. 1998 Indian J. Physiol. Pharmacol. pmid:10874348