Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

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Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

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Authors Title Published Journal PubMed Link
Verhoeven CH et al. Identification of the human P450 enzymes involved in the in vitro metabolism of the synthetic steroidal hormones Org 4060 and Org 30659. 2002 Xenobiotica pmid:11871398
Fu GM et al. [Pharmacokinetics of norethindrone-3-oxime and norethindrone in rhesus monkeys]. 1991 Yao Xue Xue Bao pmid:1887788
Liu J et al. [Pharmacokinetics of norethindrone-oxime and norethindrone in rabbits after oral administration]. 1989 Yao Xue Xue Bao pmid:2816369
Tang GP and Chen QQ [Column switching HPLC method for determination of in vivo release of norethindrone-alpha, beta-poly (3-hydroxypropyl)-DL-asparamide conjugate]. 1994 Yao Xue Xue Bao pmid:7976344
Chen W and Zhang XY [Synthesis of 11-keto-delta 9-norethisterone]. 1986 Yao Xue Xue Bao pmid:3788599
Chen W and Qiu LK [Synthesis of cyclopentylpropionic ester of norethisterone acetate as a long-acting contraceptive]. 1984 Yao Xue Xue Bao pmid:6544567
Ma XH and Qin ZL [Optimization of high-performance liquid chromatographic separation of progestogens]. 1987 Yao Xue Xue Bao pmid:3450143
Huang L et al. [Studies on long acting contraceptives: synthesis of 17 beta-steroid esters]. 1983 Yao Xue Xue Bao pmid:6677029
Wang SJ et al. [Synthesis of the anti-estrogen, delta 4-10 beta-acetoxy-17 beta-hydroxy-17 alpha-ethynyl-estren-3-one]. 1982 Yao Xue Xue Bao pmid:7136718
Kim CS and Lee YB Morphologic effects of oral contraceptives (Norinyle) on the guinea pig liver. 1980 Yonsei Med. J. pmid:7269635
Klinger G et al. [Efficacy of Non-ovlon in female patients with acne vulgaris]. 1970 Z Arztl Fortbild (Jena) pmid:4251329
Grässler W and Olthoff KH [Migraine and hormonal contraceptives]. 1984 Z Arztl Fortbild (Jena) pmid:6203234
Echtermeyer G and Sporman H [Liver tumor after long-term administration of NON OVLON]. 1981 Z Arztl Fortbild (Jena) pmid:7281743
Späth-Schwalbe E et al. [Successful treatment of recurrent lower gastrointestinal hemorrhage in intestinal angiodysplasia with an estrogen-progesterone combination]. 1993 Jul-Aug Z Gastroenterol pmid:8379233
Schneider W [Changes of bleeding rhythm in normal biphasically menstruating women during continuing administration of small gestagen doses]. 1971 Z Geburtshilfe Gynakol pmid:5157078
Pal D and Guha B Effect of progesterone (norethindrone) only oral contraceptive on mouse uterus--a SEM study. 1990 Z Mikrosk Anat Forsch pmid:2238795
Schindler C and Rodriguez L [Comparative studies of the effect on the in vitro growth of endometrial cancers of hydroxyprogesterone caproate, norethisterone acetate and D-norgestrel]. 1984 Zentralbl Gynakol pmid:6730768
Mueck AO et al. [Effect of tibolone on vascular markers of human female coronary arteries - comparison with estradiol/norethisterone]. 2001 Zentralbl Gynakol pmid:11797164
Starker W and Fricke HJ [Glucose assimilation under high-dose norethisterone-acetate therapy in adenocarcinoma of the corpus uteri]. 1979 Zentralbl Gynakol pmid:463410
Seewald HJ et al. [Results of high dosage progesterone therapy in carcinoma corporis uteri]. 1977 Zentralbl Gynakol pmid:868363