Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

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Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

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Authors Title Published Journal PubMed Link
Adamczyk M et al. O-(fluoresceinylmethyl)hydroxylamine (OFMHA): a reagent for the preparation of fluorescent O-(fluoresceinylmethyl)oxime (FMO)-steroid conjugates. 1999 Steroids pmid:10399885
Mattsson LA et al. Continuous, combined hormone replacement: randomized comparison of transdermal and oral preparations. 1999 Obstet Gynecol pmid:10389719
Sulak P et al. Clinical comparison of triphasic norgestimate/35 micrograms ethinyl estradiol and monophasic norethindrone acetate/20 micrograms ethinyl estradiol. Cycle control, lipid effects, and user satisfaction. 1999 Contraception pmid:10382078
Khan AR et al. Experience with norethisterone enanthate as injectable contraceptive. 1976 Bangladesh Med Res Counc Bull pmid:1037371
Wahrenberg H et al. Divergent effects of weight reduction and oral anticonception treatment on adrenergic lipolysis regulation in obese women with the polycystic ovary syndrome. 1999 J. Clin. Endocrinol. Metab. pmid:10372729
Gerhards E et al. Studies of the kinetics and metabolism of 17 beta-heptanoyl-17 alpha-ethinyl-4-oestren-3-one-7-3H (norethisterone enanthate) in humans following intramuscular injection. 1976 Arzneimittelforschung pmid:1036962
Johansson ED and Kral JG Oral contraceptives after intestinal bypass operations. 1976 JAMA pmid:1036586
Campos MG et al. The androgenic effect of norethisterone and 5alpha-norethisterone on the contractile response of the rat vas deferens to methoxamine and serotonin. 1999 Life Sci. pmid:10350363
Stanczyk FZ et al. Effect of oral contraceptives containing 20 and 35 micrograms ethinyl estradiol on urinary prostacyclin and thromboxane metabolite levels in smokers and nonsmokers. 1999 Contraception pmid:10342082
Scheffler MR et al. Thalidomide does not alter estrogen-progesterone hormone single dose pharmacokinetics. 1999 Clin. Pharmacol. Ther. pmid:10340913
Gruber DM et al. Endometrial cancer after combined hormone replacement therapy. 1999 Maturitas pmid:10340283
Charkoudian N and Johnson JM Altered reflex control of cutaneous circulation by female sex steroids is independent of prostaglandins. 1999 Am. J. Physiol. pmid:10330248
Pérez-Medina T et al. Atypical endometrial hyperplasia treatment with progestogens and gonadotropin-releasing hormone analogues: long-term follow-up. 1999 Gynecol. Oncol. pmid:10329050
Elstein M et al. The effect of daily norethisterone (0.35 mg) on cervical mucus and on urinary LH, pregnanediol and oestrogen levels. 1976 Br J Obstet Gynaecol pmid:1032819
Hampton AL et al. Progesterone analogues similarly modulate endometrial matrix metalloproteinase-1 and matrix metalloproteinase-3 and their inhibitor in a model for long-term contraceptive effects. 1999 Mol. Hum. Reprod. pmid:10321809
Soutoul JH et al. [Oral contraception by means of progestagen-only micropills taken continuously in the light of four recent trials (author's transl)]. 1976 Rev Fr Gynecol Obstet pmid:1023328
Fender GR et al. Randomised controlled trial of educational package on management of menorrhagia in primary care: the Anglia menorrhagia education study. 1999 BMJ pmid:10231255
Barditch-Crovo P et al. The effects of rifampin and rifabutin on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive. 1999 Clin. Pharmacol. Ther. pmid:10223781
Franklin RD and Kutteh WH Characterization of immunoglobulins and cytokines in human cervical mucus: influence of exogenous and endogenous hormones. 1999 J. Reprod. Immunol. pmid:10221733
Loi CM et al. Effect of troglitazone on the pharmacokinetics of an oral contraceptive agent. 1999 J Clin Pharmacol pmid:10197300