Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

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Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Norethindrone?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

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Authors Title Published Journal PubMed Link
Allen WE Effect of implanted progesterone pellets on plasma progestogen concentrations in anoestrous pony mares. 1982 Equine Vet. J. pmid:7201921
Peter H et al. Norethisterone-4 beta,5-oxide and laevonorgestrel-4 beta,5-oxide: formation in rat liver microsomal incubations and interference with microsomal epoxide hydrolase and cytoplasmic glutathione S-transferase. 1981 J. Steroid Biochem. pmid:7206700
Silfverstolpe G et al. Lipid metabolic studies in oophorectomized women. Effects induced by the addition of norethisterone acetate to two different oestrogens on serum individual phospholipids and serum lecithin fatty acid composition. 1981 Acta Endocrinol. pmid:7211107
Beck LR and Cowsar D Biodegradable microsphere contraceptive system. 1980 Acta Eur. Fertil. pmid:7211111
Dickerson J et al. Liver function tests and low-dose estrogen oral contraceptives. 1980 Contraception pmid:7214908
Joshi JV et al. A study of interaction of low-dose combination oral contraceptive with Ampicillin and Metronidazole. 1980 Contraception pmid:7214911
Srivastava UK and Mendiratta R Effect of norethisterone enanthate subdermal silastic implants on the ovary & uterus of adult rabbits. 1980 Indian J. Exp. Biol. pmid:7216278
Schindler C [Use of gestagens to control in vitro growth of endometrial carcinoma (author's transl)]. 1981 Zentralbl Gynakol pmid:7223173
Murphy HM Effect of norethisterone on puerperal vaginal bleeding. 1980 Ir J Med Sci pmid:7228589
Meade TW et al. Haemostatic, lipid, and blood-pressure profiles of women on oral contraceptives containing 50 microgram or 30 microgram oestrogen. 1977 Lancet pmid:72289
Back DJ et al. Studies on the enzymatic cleavage of norethisterone oenanthate. 1981 Contraception pmid:7238040
Kumar D et al. Fluid-filled silastic capsules : a new approach to a more constant steroidal drug delivery system. 1981 Contraception pmid:7238045
Sarkar NN et al. Bioavailability of norethindrone in rabbits after administration of norethindrone acetate in single, double and quadruple doses released through subcutaneous silastic implants. 1980 Endocrinol. Jpn. pmid:7238423
Correia MA et al. Cytochrome P-450 heme moiety. The specific target in drug-induced heme alkylation. 1981 J. Biol. Chem. pmid:7240150
Wren BG Minimal dose combined hormonal replacement therapy for menopausal women. 1981 Med. J. Aust. pmid:7242418
Claessens EA and Cowell CA Dysfunctional uterine bleeding in the adolescent. 1981 Pediatr. Clin. North Am. pmid:7243368
Bélanger A et al. Regio and stereospecific synthesis of 11 beta-substituted 19-norsteroids. Influence of 11 beta-substitution on progesterone receptor affinity - (1). 1981 Steroids pmid:7245285
Zheleznov BI and Beliaeva LA [Effect of progesterone and norethisterone on the DNA content in organ cultures of hyperplastically altered endometrium]. 1981 Akush Ginekol (Mosk) pmid:7246930
Makatsariia AD et al. [State of the hemostatic system in genital endometriosis patients taking large doses of gestagens]. 1981 Akush Ginekol (Mosk) pmid:7246933
Chalupa M [Contraception with Monogest in young women]. 1981 Cesk Gynekol pmid:7249099
Kasid A and Laumas KR Nuclear progestin receptors in human uterus. 1981 Endocrinology pmid:7250058
Sundaresan GM et al. Simple high-performance liquid chromatographic assay for norethindrone--mestranol in combination tablets. 1981 J Pharm Sci pmid:7252827
Ylöstalo P et al. Serum bile acids and lipids during treatment of climacteric symptoms with natural oestrogen--progestin combinations. 1981 Maturitas pmid:7253932
Watanabe H et al. Identification of hydrazone of norethindrone, a metabolic product resulting from the interaction between isoniazid and norethindrone. 1981 Res. Commun. Chem. Pathol. Pharmacol. pmid:7255877
Moore B et al. The effect of menopausal status and sequential mestranol and norethisterone on serum biochemical profiles. 1981 Br J Obstet Gynaecol pmid:7260006
Møller SE Effect of oral contraceptives on tryptophan and tyrosine availability: evidence for a possible contribution to mental depression. 1981 Neuropsychobiology pmid:7266825
Dalén N et al. Changes in bone mineral content in women with natural menopause during treatment with female sex hormones. 1978 Acta Obstet Gynecol Scand pmid:726877
Ratnam SS et al. Alternatives to female sterilization. 1977 Int J Gynaecol Obstet pmid:72691
Kim CS and Lee YB Morphologic effects of oral contraceptives (Norinyle) on the guinea pig liver. 1980 Yonsei Med. J. pmid:7269635
Sang GW et al. Pharmacokinetics of norethisterone oenanthate in humans. 1981 Contraception pmid:7273765
Landgren BM et al. Pharmacokinetic and pharmacodynamic studies with vaginal devices releasing norethisterone at a constant, near zero order. 1981 Contraception pmid:7273766
Kuhl H et al. Reversible inhibition of spermatogenesis by a long-acting dimeric ethynodiol-testosterone ester. 1981 Contraception pmid:7273768
Trisequens. 1981 Drug Ther Bull pmid:7274066
Srivastava UK Contraceptive efficacy of microdose norethisterone enanthate: a study on its use in polydimethylsiloxane implants. 1981 Indian J. Exp. Biol. pmid:7275203
Julien J et al. [Cerebral vascular accident during progestational therapy]. 1981 Aug 29-Sep 5 Nouv Presse Med pmid:7279642
Echtermeyer G and Sporman H [Liver tumor after long-term administration of NON OVLON]. 1981 Z Arztl Fortbild (Jena) pmid:7281743
Schindler C and Schober J [Results obtained from gestagen treatment of patients for endometrial carcinoma, with particular reference to results obtained from in vitro tests before treatment (author's transl)]. 1981 Zentralbl Gynakol pmid:7282171
Christiansen C et al. Effects of natural estrogen/gestagen and thiazide on coronary risk factors in normal postmenopausal women. A 2-year double-blind placebo study. 1981 Acta Obstet Gynecol Scand pmid:7282308
Zizkovská E et al. [Minigest--a new Czechoslovak contraceptive and its side-effects (author's transl)]. 1980 Cesk Gynekol pmid:7285155
Kobilková J et al. [Biochemical and steroidal indicators in the use of Monogest, a progesterone contraceptive]. 1981 Cesk Gynekol pmid:7285177
Fotherby K et al. Pharmacokinetics of ethynyloestradiol in women for different populations. 1981 Contraception pmid:7285572
Prasad KV et al. Plasma levels of norethidrone in Indian women receiving norethidrone enanthate (20 mg) injectable. 1981 Contraception pmid:7285573
Watanabe H et al. An investigation of the interaction between isoniazid and the contraceptive steroid norethindrone in vivo. 1981 Experientia pmid:7286144
Srivastava UK Effect of intramuscular norethisterone enanthate on compensatory ovarian hypertrophy in the rat. 1981 Apr-Jun Indian J. Physiol. Pharmacol. pmid:7287136
Srivastava UK Long-term regulation of male fertility by norethisterone enanthate 'epididymal' implants: effect on libido and fertility of rabbits. 1981 Apr-Jun Indian J. Physiol. Pharmacol. pmid:7287137
Gruhn K et al. [Effect of contraceptives on the digestibility of dietary protein and nitrogen balance]. 1981 Nahrung pmid:7290175
Giwa-Osagie OF et al. Norethisterone oenanthate as an injectable contraceptive: a study of patients discontinuing treatment. 1978 Contraception pmid:729377
Fotherby K et al. Occurrence of ovulation in women receiving the injectable contraceptive norethisterone oenanthate. 1978 Contraception pmid:729379
Zhou JY [Colposcopic study of the effect of steroid contraceptives on the uterine cervix (author's transl)]. 1981 Zhonghua Fu Chan Ke Za Zhi pmid:7297239
Progestagens, blood-clotting, and blood-pressure. 1977 Lancet pmid:72996
Christiansen C et al. [Effects of natural estrogen/gestagen and thiazide on cardiovascular risk factors in normal menopausal women. A 2-year double-blind placebo study]. 1981 Ugeskr. Laeg. pmid:7303230
Sengupta D et al. Effect of norethindrone acetate on glycogen & phosphorylase of adult rat testes & epididymis. 1981 Indian J. Exp. Biol. pmid:7309151
Whitehead MI et al. Effects of estrogens and progestins on the biochemistry and morphology of the postmenopausal endometrium. 1981 N. Engl. J. Med. pmid:7312007
Stricker SJ et al. "Effort thrombosis" of the subclavian vein associated with oral contraceptives. 1981 Ann Emerg Med pmid:7316265
White IN Destruction of liver haem by norethindrone. Conversion into green pigments. 1981 Biochem. J. pmid:7316996
Yasuda J et al. [Pharmacokinetics of norethindrone and lynestrenol studied by HPLC (author's transl)]. 1981 Nihon Naibunpi Gakkai Zasshi pmid:7319102
Lunstra DD and Christenson RK Synchronization of ewes during anestrus: influence of time of year and interval to onset of estrus on conception rate. 1981 J. Anim. Sci. pmid:7319947
Maiti BR and Sahu A Effects of a long-term treatment with norethisterone (a progestogen-only contraceptive) on the epidermis, the sebaceous glands, the meibomian gland and the Harderian gland in the cycling female rat. 1981 Mikroskopie pmid:7322374
Pal MN and Pal I Menstrual behaviour with steroid implant. 1981 J Indian Med Assoc pmid:7328324
Lara Ricalde R et al. [Intrauterine devices and endometrial infection]. 1981 Ginecol Obstet Mex pmid:7333494
Yasuzumi G et al. In vivo production of nucleolar channel system in human endocervical secretory cells. 1981 J. Submicrosc. Cytol. pmid:7334554
Hodes ME et al. Trisomy 7 mosaicism and manifestations of Goldenhar syndrome with unilateral radial hypoplasia. 1981 J. Craniofac. Genet. Dev. Biol. pmid:7341641
Akhter N and Choudhury SA Effect of norethisterone oenanthate-a long acting injectable contraceptive on cervical mucus changes in adult female virgin rats. 1981 Bangladesh Med Res Counc Bull pmid:7347605
Braverman DZ et al. Effects of pregnancy and contraceptive steroids on gallbladder function. 1980 N. Engl. J. Med. pmid:7351927
Hall WD et al. Blood pressure and oral progestational agents. A prospective study of 119 black women. 1980 Am. J. Obstet. Gynecol. pmid:7352524
Solmonson SR and Shank JC Eosinophilic pneumonia. 1980 J Fam Pract pmid:7354288
White IN Chemical reactivity and metabolism of norethindrone-4 beta,5 beta-epoxide by rat liver microsomes in vitro. 1980 Chem. Biol. Interact. pmid:7356533
Landgren BM and Diczfalusy E Hormonal effects of the 300 microgram norethisterone (NET) minipill. I. Daily steroid levels in 43 subjects during a pretreatment cycle and during the second month of NET administration. 1980 Contraception pmid:7357872
Srivastava UK and Malaviya B Effect of chronic local administration of norethisterone enanthate on the testes of adult rat. 1980 Jan-Mar Indian J. Physiol. Pharmacol. pmid:7364460
Bohnet HG et al. Effects of synthetic gestagens on serum prolactin and growth hormone secretion in amenorrheic patients. 1978 Arch. Gynecol. pmid:736621
Nordin BE et al. Treatment of spinal osteoporosis in postmenopausal women. 1980 Br Med J pmid:7370532
el-Mahgoub S Body weight and cycle control of injectable contraceptives. 1980 J Reprod Med pmid:7373592
LandekhovskiÄ­ IuD and ZaÄ­dieva IaZ [Characteristics of the volemic shifts during the use of norethisterone in the process of the dispensary management of uterine myoma]. 1980 Akush Ginekol (Mosk) pmid:7377468
Kondrikov NI and Trutko NS [Morphological and biochemical characteristics of the endometrium of women taking small doses of norethisterone]. 1980 Akush Ginekol (Mosk) pmid:7377479
Zheleznov BI and Beliaeva LA [Changes in the endometrial proliferative processes under the influence of progesterone and norethisterone in an organ culture]. 1980 Akush Ginekol (Mosk) pmid:7377496
White IN and Suzangar M Cytotoxic effects of norethindrone-4 beta,5 beta-epoxide to Walker cells in culture and to rat liver in vivo. 1980 Chem. Biol. Interact. pmid:7379214
Back DJ et al. Reduction of the enterohepatic circulation of norethisterone by antibiotics in the rat: correlation with changes in the gut flora. 1980 J. Steroid Biochem. pmid:7382487
Chatterjee SK Scar endometriosis: a clinicopathologic study of 17 cases. 1980 Obstet Gynecol pmid:7383492
Holbek S and Obel EB [Depot gestagens as contraceptives]. 1980 Ugeskr. Laeg. pmid:7385396
Prilepskaia VN [Restoration of the reproductive function in dysfunctional uterine hemorrhage patients under gestagenic steroid treatment]. 1980 Vopr Okhr Materin Det pmid:7385674
Kanke Y et al. Oral contraceptive steroids: effects on iron and zinc levels and on tryptophan pyrrolase and alkaline phosphatase activities in tissues of iron-deficient anemic rats. 1980 Am. J. Clin. Nutr. pmid:7386413
Barros D'Sa AA The pill, mesenteric vein thrombosis and the short, short bowel syndrome. 1980 Br J Clin Pract pmid:7387823
Meade TW et al. Progestogens and cardiovascular reactions associated with oral contraceptives and a comparison of the safety of 50- and 30-microgram oestrogen preparations. 1980 Br Med J pmid:7388443
Toddywalla VS et al. Release of 19-nor-testosterone type of contraceptive steroids through different drug delivery systems into serum and breast milk of lactating women. 1980 Contraception pmid:7389350
Werawatgoompa S et al. The effect of injectable norethisterone oenanthate on ovarian hormones in Thai women. 1980 Contraception pmid:7389353
Hirai S et al. Sensitive method for determination of ethinyl estradiol in presence of norethindrone. 1980 J Pharm Sci pmid:7391956
Feijen J et al. Coupling of steroid hormones to biodegradable poly (alpha-amino acids) I: Norethindrone coupled to poly-N5-(3-hydroxypropyl)-L-glutamine. 1980 J Pharm Sci pmid:7391961
Khan FS and Fotherby K In vitro hydrolysis of 19-norsteroid esters. 1980 J. Steroid Biochem. pmid:7392623
Briggs M and Briggs M Oestrogen content of oral contraceptives. 1977 Lancet pmid:73934
Mishell DR New frontiers of contraception. 1978 J Reprod Med pmid:739490
Maiti BR Effect of prolonged treatment of norethisterone (a progestogen-only contraceptive) on the thyro-follicular activity of rat. 1980 Acta Anat (Basel) pmid:7395448
Dove DJ Chorea associated with oral contraceptive therapy. 1980 Am. J. Obstet. Gynecol. pmid:7395941
Back DJ et al. Phenobarbitone interaction with oral contraceptive steroids in the rabbit and rat. 1980 Br. J. Pharmacol. pmid:7397454
Aylward M Coagulation factors in opposed and unopposed oestrogen treatment at the climacteric. 1978 Postgrad Med J pmid:740578
Fotherby K et al. A preliminary pharmacokinetic and pharmacodynamic evaluation of depot-medroxyprogesterone acetate and norethisterone oenanthate. 1980 Fertil. Steril. pmid:7409232
Crews MG et al. Effects of oral contraceptive agents on copper and zinc balance in young women. 1980 Am. J. Clin. Nutr. pmid:7416062
Schardein JL Studies of the components of an oral contraceptive agent in albino rats. II. Progestogenic component and comparison of effects of the components and the combined agent. 1980 J Toxicol Environ Health pmid:7420489
Varini M et al. [Oral gestagen treatment of advanced breast neoplasms with norethisterone acetate]. 1980 Schweiz Med Wochenschr pmid:7423152
A randomized, double-blind study of two combined oral contraceptives containing the same progestogen, but different estrogens. World Health Organization Task Force on Oral Contraception. 1980 Contraception pmid:7428356
Guirgis FK et al. Serum phospholipid fractionation after the use of long-acting progestational contraceptives. 1980 Contraception pmid:7428358