| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
Total
3
Norethindrone
Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.
Cross Reference
Introduction
To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Norethindrone?
Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Norethindrone
PubChem Associated disorders and diseases
What pathways are associated with Norethindrone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Norethindrone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Norethindrone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Norethindrone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Norethindrone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Norethindrone?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Norethindrone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Williams JG et al. | Metabolism of 4-3-H- and 4-14-C-17alpha-ethynylestradiol 3-methyl ether (mestranol) by women. | 1975 | Steroids | pmid:1145671 |
| KratochvÃl P et al. | Sustained release hormonal preparations. 6. Permeability constant of various steroids. | 1970 | Steroids | pmid:5446544 |
| Briggs MH | Steroid hormones and the fertilizing capacity of spermatozoa. | 1973 | Steroids | pmid:4127001 |
| Stanczyk FZ | All progestins are not created equal. | 2003 | Steroids | pmid:14667980 |
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| Gal D et al. | Failure of contraceptive steroids to modify human chorionic gonadotrophin secretion by hydatidiform mole tissue and choriocarcinoma cells in culture. | 1981 | Steroids | pmid:7027540 |
| Djerassi C | Steroid research at Syntex: "the pill" and cortisone. | 1992 | Steroids | pmid:1481227 |
| Bélanger A et al. | Regio and stereospecific synthesis of 11 beta-substituted 19-norsteroids. Influence of 11 beta-substitution on progesterone receptor affinity - (1). | 1981 | Steroids | pmid:7245285 |
| Kappus H and Bolt HM | Irreversible protein binding of norethisterone (norethindrone) epoxide. | 1976 | Steroids | pmid:4905 |
| Joshi JV et al. | Serum progesterone and norethisterone levels following injection of norethisterone enanthate in different sites and doses. | 1989 | Steroids | pmid:2815152 |
| Müller J and Herz JE | Preparation of highly hindered steroid esters: application of some newer methods of esterification. | 1979 | Steroids | pmid:538779 |
| Johnston JO et al. | Regioselectivity of metabolic activation of acetylenic steroids by hepatic cytochrome P450 isozymes. | 1991 | Steroids | pmid:1871782 |
| Matlin SA et al. | Long-acting contraceptive agents: analysis and purification of steroid esters. | 1983 | Steroids | pmid:6419409 |
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| Bialy G et al. | Long-acting contraceptive agents: structure activity relationships in a series of norethisterone and levonorgestrel esters. | 1983 | Steroids | pmid:6419411 |
| Walker CJ et al. | Doping in sport--2. Quantification of the impurity 19-norandrostenedione in pharmaceutical preparations of norethisterone. | 2009 | Steroids | pmid:19010341 |
| Farkas E and O'Toole DJ | 17 alpha-ethynyl-17 beta-hydroxy-10 alpha-estr-4-en-3-one. | 1971 | Steroids | pmid:5551842 |
| Jones RC et al. | An assay for progestagens by the intravenous route. | 1966 | Steroids | pmid:5962978 |
| Watanabe H et al. | Distribution of radioactivity in rat tissues after administration of tritiated 17-alpha-ethynyl-19-norsteroids. | 1968 | Steroids | pmid:5641818 |
| Vincze I et al. | Steroids 49. Investigations on the dehydration of 17 alpha-ethynyl-17 beta-hydroxysteroids. | 1993 | Steroids | pmid:8356574 |
| de Gooyer ME et al. | Tibolone is not converted by human aromatase to 7alpha-methyl-17alpha-ethynylestradiol (7alpha-MEE): analyses with sensitive bioassays for estrogens and androgens and with LC-MSMS. | 2003 | Steroids | pmid:12628686 |
| Rao PN | Preparation of 9-alpha,11-xi-tritiated 17-alpha-ethynylestradiol, mestranol, estradiol-alpha-17-beta, and norethindrone. | 1971 | Steroids | pmid:5126820 |
| Sasagawa S et al. | Dienogest is a selective progesterone receptor agonist in transactivation analysis with potent oral endometrial activity due to its efficient pharmacokinetic profile. | 2008 | Steroids | pmid:18061638 |
| Ekhato IV et al. | Norethindrone acetate (NA) and ethinyl estradiol (EE) related oxidative transformation products in stability samples of formulated drug product: synthesis of authentic references. | 2002 | Steroids | pmid:11856540 |
| Curts SW et al. | Synthesis of 5 beta,17 alpha-19-norpregn-20-yne-3 beta,17-diol and of 5 beta,17 alpha-19-norpregn-20-yne-3 alpha,17-diol, human metabolites of norethindrone. | 1991 | Steroids | pmid:2028483 |
| Williams JG and Williams KI | Metabolism of 2-3H- and 4-14C-17alpha-ethynylestradiol 3-methyl ether (mestranol) by women. | 1975 | Steroids | pmid:1216258 |
| Walker CJ et al. | Doping in sport: 3. Metabolic conversion of oral norethisterone to urinary 19-norandrosterone. | 2009 | Steroids | pmid:19059424 |
| Walker CJ et al. | Doping in sport--1. Excretion of 19-norandrosterone by healthy women, including those using contraceptives containing norethisterone. | 2009 | Steroids | pmid:19010339 |
| DiNunno CM et al. | 7 alpha-Methylnorethindrone enanthate 10 beta-hydroperoxide: isolation and characterization. | 1983 | Steroids | pmid:6689617 |
| Raobaikady B et al. | Lack of aromatisation of the 3-keto-4-ene metabolite of tibolone to an estrogenic derivative. | 2006 | Steroids | pmid:16712888 |
| Crabbé P et al. | Long-acting contraceptive agents: design of the WHO Chemical Synthesis Programme. | 1983 | Steroids | pmid:6658872 |
| Adamczyk M et al. | O-(fluoresceinylmethyl)hydroxylamine (OFMHA): a reagent for the preparation of fluorescent O-(fluoresceinylmethyl)oxime (FMO)-steroid conjugates. | 1999 | Steroids | pmid:10399885 |
| Watson TG et al. | Long-acting contraceptive agents: esters of norethisterone with alpha- and/or beta-chain branching. | 1983 | Steroids | pmid:6658873 |
| Herz JE et al. | Esterification of acid chlorides with thallium and potassium salts of 19-norethisterone: formation of 17-enol esters. | 1982 | Steroids | pmid:7184202 |
| Francisco CG et al. | Long-acting contraceptive agents: norethisterone esters of monoalkenyl and monoalkynyl acids. | 1983 | Steroids | pmid:6658874 |
| Francisco CG et al. | Long-acting contraceptive agents: norethisterone esters of polyunsaturated acids. | 1983 | Steroids | pmid:6658875 |
| Terenius L | Specific progestogen binder in uterus of normal rats. | 1972 | Steroids | pmid:4114433 |
| Robin JC et al. | Studies on osteoporosis X. Effect of estrogen-progestin combination on heparin-induced osteoporosis. | 1983 | Steroids | pmid:6098977 |
| Turkes A et al. | A sensitive solid phase enzymeimmunoassay for norethisterone (norethindrone) in saliva and plasma. | 1980 | Steroids | pmid:6990558 |
| Herz JE et al. | Long-acting contraceptive agents: carbonates and carbamates of norethisterone. | 1983 | Steroids | pmid:6658881 |
| Enever RP and Lewis GA | Long-acting contraceptive agents: the influence of pharmaceutical formulation upon biological activity of esters of norethisterone. | 1983 | Steroids | pmid:6658882 |
| Enever RP et al. | Long-acting contraceptive agents: the influence of physico-chemical properties of some esters of norethisterone upon the plasma levels of free norethisterone. | 1983 | Steroids | pmid:6658883 |
| Garza-Flores J et al. | A rapid and sensitive radioimmunoassay for norethisterone. | 1983 | Steroids | pmid:6665817 |
| Kincl FA et al. | Sustained release hormonal preparations. 1. Diffusion of various steroids through polymer membranes. | 1968 | Steroids | pmid:5650692 |
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| Bruno RD et al. | Synthesis and biological evaluations of putative metabolically stable analogs of VN/124-1 (TOK-001): head to head anti-tumor efficacy evaluation of VN/124-1 (TOK-001) and abiraterone in LAPC-4 human prostate cancer xenograft model. | 2011 | Steroids | pmid:21729712 |
| Düsterberg B | Plasma levels of levonorgestrel, gestodene, norethisterone and cyproterone acetate on single-dose subcutaneous administration in oily solution in the rat, beagle and rhesus monkey. | 1984 | Steroids | pmid:6240802 |
| Banerjee RC et al. | Effects of norethindrone (17-ethynyl-17 -hydroxy-4-estren-3-one) and norgestrel (dl-13 -ethyl-17-ethynyl-17 -hydroxy-4-gonen-3-one) on the tissue distribution of 3 H-estradiol-17 in ovariectomized rats. | 1973 | Steroids | pmid:4687305 |
| Watanabe H | The in vitro inhibition of estrogen transformations in rat liver by 17-alpha-ethynyl-19-norsteroids. | 1969 | Steroids | pmid:5773889 |
| Cooper GF | Synthesis of 5,17-dihydroxy-5 alpha, 17 alpha,-19-norpregn-20-yn-3-one, a major photodegradation product of norethindrone. | 1988 May-Jun | Steroids | pmid:3242171 |