| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
Total
3
Norethindrone
Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.
Cross Reference
Introduction
To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Norethindrone?
Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Norethindrone
PubChem Associated disorders and diseases
What pathways are associated with Norethindrone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Norethindrone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Norethindrone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Norethindrone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Norethindrone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Norethindrone?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Norethindrone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hassan EO et al. | Acceptability of the once-a-month injectable contraceptives Cyclofem and Mesigyna in Egypt. | 1994 | Contraception | pmid:8045133 |
| Lau KH et al. | Picomolar norethindrone in vitro stimulates the cell proliferation and activity of a human osteosarcoma cell line and increases bone collagen synthesis without an effect on bone resorption. | 1994 | J. Bone Miner. Res. | pmid:8053399 |
| Schvarc F et al. | [Dynamics of changes in the uterine glands of ewes during chlorsuperlutine-synchronized estrus]. | 1975 | Vet Med (Praha) | pmid:808010 |
| Chinvanthananond P | Endometrial pattern in long-term users of NET-EN. | 1993 | J Med Assoc Thai | pmid:8089639 |
| Doyle LL et al. | Selection of steroids for incorporation into silastic intrauterine devices. | 1975 | J. Steroid Biochem. | pmid:809619 |
| Malhi JS et al. | The effects of antibiotics and steroids on the carriage of vaginal bacteria into the uterus during insertion of intra-uterine monofilaments in the guinea-pig. | 1993 | J. Pharm. Pharmacol. | pmid:8105064 |
| Lehmann R et al. | Effect of norethisterone acetate on serum lipid and lipoprotein parameters as well as on blood coagulation in female monkeys (M. fascicularis). | 1993 | Contraception | pmid:8131398 |
| Walle UK et al. | The influence of gender and sex steroid hormones on the plasma binding of propranolol enantiomers. | 1994 | Br J Clin Pharmacol | pmid:8148214 |
| Bentley GR | Ranging hormones: do hormonal contraceptives ignore human biological variation and evolution? | 1994 | Ann. N. Y. Acad. Sci. | pmid:8154705 |
| Shoupe D | Multicenter randomized comparative trial of two low-dose triphasic combined oral contraceptives containing desogestrel or norethindrone. | 1994 | Obstet Gynecol | pmid:8164925 |
| al-Azzawi F et al. | Investigation of the bleeding patterns of postmenopausal women treated with Estrapak-50. | 1994 | Maturitas | pmid:8177092 |
| Darney PD | Hormonal implants: contraception for a new century. | 1994 | Am. J. Obstet. Gynecol. | pmid:8178903 |
| Wiseman LR and McTavish D | Transdermal estradiol/norethisterone. A review of its pharmacological properties and clinical use in postmenopausal women. | 1994 | Drugs Aging | pmid:8199397 |
| Gold E et al. | Tamoxifen and norethisterone: effects on plasma cholesterol and total body calcium content in the estrogen-deficient rat. | 1994 | Horm. Metab. Res. | pmid:8200611 |
| Beaumont JL and Lemort N | Oral contraceptive, pulmonary artery thrombosis and anti-ethinyl-oestradiol monoclonal IgG. | 1976 | Clin. Exp. Immunol. | pmid:820501 |
| Yamamoto T et al. | Suicide inactivation of aromatase in human placenta and uterine leiomyoma by 5 alpha-dihydronorethindrone, a metabolite of norethindrone, and its effect on steroid-producing enzymes. | 1994 | Eur. J. Endocrinol. | pmid:8205267 |
| Burckhardt P et al. | Estrogen-induced tetany in idiopathic hypoparathyroidism. | 1975 | Horm. Res. | pmid:820624 |
| Dorantes A and Stavchansky S | Modification of the U.S.P. dissolution method for the analysis of norethindrone and ethinyl estradiol tablets. | 1994 | J Pharm Sci | pmid:8207685 |
| Wiik P et al. | Effect of norethisterone and levonorgestrel in low-dose multiphasic oral contraceptives on serum lipids. | 1993 | Acta Obstet Gynecol Scand | pmid:8213103 |
| Weber-Diehl F et al. | Comparison of two triphasic oral contraceptives containing either gestodene or norethindrone: a randomized, controlled trial. | 1993 | Contraception | pmid:8222658 |
| Higham JM and Shaw RW | A comparative study of danazol, a regimen of decreasing doses of danazol, and norethindrone in the treatment of objectively proven unexplained menorrhagia. | 1993 | Am. J. Obstet. Gynecol. | pmid:8238173 |
| Riggs BL | Formation-stimulating regimens other than sodium fluoride. | 1993 | Am. J. Med. | pmid:8256799 |
| Zhou Z et al. | Evaluation of 90:10 poly(D,L-lactide-co-glycolide) microspheres containing norethisterone: drug release and biodegradation. | 1993 | Biomater Artif Cells Immobilization Biotechnol | pmid:8260576 |
| Kojima T et al. | Insulin sensitivity is decreased in normal women by doses of ethinyl estradiol used in oral contraceptives. | 1993 | Am. J. Obstet. Gynecol. | pmid:8267059 |
| Manninen V and Mälkönen M | Hormones and high-density lipoproteins. | 1978 | Lancet | pmid:82719 |
| Grimes DA et al. | Ovulation and follicular development associated with three low-dose oral contraceptives: a randomized controlled trial. | 1994 | Obstet Gynecol | pmid:8272303 |
| Horowitz M et al. | Effects of norethisterone on bone related biochemical variables and forearm bone mineral in post-menopausal osteoporosis. | 1993 | Clin. Endocrinol. (Oxf) | pmid:8287582 |
| Oliveira MC et al. | Progestin effects on prolactin secretion and on immunoreactive prolactin cells in estradiol-treated ovariectomized rats. | 1993 | Horm. Metab. Res. | pmid:8288167 |
| Heinonen OP et al. | Cardiovascular birth defects and antenatal exposure to female sex hormones. | 1977 | N. Engl. J. Med. | pmid:830309 |
| MacDonald AG et al. | Effects of hormone replacement therapy in rheumatoid arthritis: a double blind placebo-controlled study. | 1994 | Ann. Rheum. Dis. | pmid:8311557 |
| Facts about once-a-month injectable contraceptives: memorandum from a WHO meeting. | 1993 | Bull. World Health Organ. | pmid:8313486 | |
| Graham CA and Sherwin BB | The relationship between mood and sexuality in women using an oral contraceptive as a treatment for premenstrual symptoms. | 1993 | Psychoneuroendocrinology | pmid:8316616 |
| Saleh WA et al. | A randomized trial of three oral contraceptives: comparison of bleeding patterns by contraceptive types and steroid levels. | 1993 | Am. J. Obstet. Gynecol. | pmid:8317516 |
| Miyamoto J | Sex steroids and thyroid function tests: the role of estrogen and progestogen. | 1978 | Int J Gynaecol Obstet | pmid:83257 |
| Valette A et al. | Norethindrone alters apolipoprotein E concentration and isoform expression in rat plasma high-density lipoproteins. | 1993 | Life Sci. | pmid:8326818 |
| Dhall K et al. | Short-term effects of norethisterone oenanthate and medroxyprogesterone acetate on glucose, insulin, growth hormone, and lipids. | 1977 | Fertil. Steril. | pmid:832727 |
| Song S et al. | Effects of different doses of norethisterone on ovarian function, serum sex hormone binding globulin and high density lipoprotein-cholesterol. | 1993 | Contraception | pmid:8334889 |
| MacLennan AH et al. | Continuous low-dose oestrogen and progestogen hormone replacement therapy: a randomised trial. | 1993 | Med. J. Aust. | pmid:8336583 |
| Toddywalla VS et al. | Effect of contraceptive steroids on human lactation. | 1977 | Am. J. Obstet. Gynecol. | pmid:835620 |
| Vincze I et al. | Steroids 49. Investigations on the dehydration of 17 alpha-ethynyl-17 beta-hydroxysteroids. | 1993 | Steroids | pmid:8356574 |
| Corcoran R and Rizk MW | Low-dose progestogens and ectopic pregnancy. | 1977 | Br Med J | pmid:837112 |
| Koh KS and Danzinger RG | Massive intestinal infarction in young women: complication of use of oral contraceptives? | 1977 | Can Med Assoc J | pmid:837318 |
| Ford JJ and Schanbacher BD | Luteinizing hormone secretion and female lordosis behavior in male pigs. | 1977 | Endocrinology | pmid:837872 |
| Kukhtevich AV et al. | [Nephropathy-related disorders of physical and sexual development in girls: experience with successful stimulation by zinc, parlodel and norcolut]. | 1993 | Ter. Arkh. | pmid:8378851 |
| Späth-Schwalbe E et al. | [Successful treatment of recurrent lower gastrointestinal hemorrhage in intestinal angiodysplasia with an estrogen-progesterone combination]. | 1993 Jul-Aug | Z Gastroenterol | pmid:8379233 |
| Poindexter AN et al. | The effects of a long-acting progestin on the hypothalamic-pituitary-ovarian axis in women with normal menstrual cycles. | 1993 | Contraception | pmid:8403904 |
| Dunson TR et al. | A comparative study of two low-dose combined oral contraceptives: results from a multicenter trial. | 1993 | Contraception | pmid:8403908 |
| Kekkonen R et al. | Sequential regimen of the antiprogesterone RU486 and synthetic progestin for contraception. | 1993 | Fertil. Steril. | pmid:8405512 |
| Ross AH et al. | Comparison of transdermal and oral sequential gestagen in combination with transdermal estradiol: effects on bleeding patterns and endometrial histology. | 1993 | Obstet Gynecol | pmid:8414325 |
| Leather AT et al. | The prevention of bone loss in young women treated with GnRH analogues with "add-back" estrogen therapy. | 1993 | Obstet Gynecol | pmid:8416441 |
| Ditkoff EC et al. | Time-resolved fluoroimmunoassay compared with radioimmunoassay of luteinizing hormone. | 1993 | Fertil. Steril. | pmid:8425623 |
| Hammitt DG et al. | Maturational asynchrony between oocyte cumulus-coronal morphology and nuclear maturity in gonadotropin-releasing hormone agonist stimulations. | 1993 | Fertil. Steril. | pmid:8425634 |
| Opheim LN | Determination of noretisterone in tablets by differential pulse polarography. | 1977 | Anal. Chim. Acta | pmid:842864 |
| Obel EB et al. | A two-year double-blind controlled study of the clinical effect of combined and sequential postmenopausal replacement therapy and steroid metabolism during treatment. | 1993 | Maturitas | pmid:8429800 |
| Masson S et al. | A clinical comparison of two triphasic oral contraceptives with levonorgestrel or norethindrone: a prospective, randomized, single-blind study. | 1993 | Contraception | pmid:8436001 |
| Houdek J et al. | [Changes in the biochemical properties of cervical mucus occurring during the use of minitabled-based contraception (author's transl)]. | 1977 | Cesk Gynekol | pmid:844108 |
| Houdek J et al. | [Ultrastructure of endometrium during low-dose gestagenic anticonception (author's transl)]. | 1977 | Cesk Gynekol | pmid:844109 |
| Bain SD et al. | High-dose gestagens modulate bone resorption and formation and enhance estrogen-induced endosteal bone formation in the ovariectomized mouse. | 1993 | J. Bone Miner. Res. | pmid:8442440 |
| Kakis G et al. | A randomized comparative open study of the effects of two oral contraceptives, Triphasil and Ortho 7/7/7, on lipid metabolism. | 1993 | Contraception | pmid:8449014 |
| Surrey ES et al. | Effects of sodium etidronate in combination with low-dose norethindrone in patients administered a long-acting GnRH agonist: a preliminary report. | 1993 | Obstet Gynecol | pmid:8459971 |
| Zhou Z et al. | Preparation and evaluation in vitro and vivo of copoly (lactic/glycolic) acid microspheres containing norethisterone. | 1993 | Biomater Artif Cells Immobilization Biotechnol | pmid:8461438 |
| Anderson FD et al. | Tissue response to bioerodible, subcutaneous drug implants: a possible determinant of drug absorption kinetics. | 1993 | Pharm. Res. | pmid:8464809 |
| Nakamura Y et al. | [A case of pulmonary embolism probably induced by long term use of oral contraceptive]. | 1993 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:8468829 |
| Nesbit RR and Deweese JA | Mesenteric venous thrombosis and oral contraceptives. | 1977 | South. Med. J. | pmid:847490 |
| Bakos T et al. | Steroids 51. An improved synthesis of ORG 2058 and the synthesis of [3H]ORG 2058. | 1993 | Steroids | pmid:8475515 |
| Goulding A and Gold E | Norethindrone acetate only partially protects the skeleton of rats treated with the LHRH agonist buserelin from oestrogen-deficiency osteopaenia. | 1993 | J. Endocrinol. | pmid:8492074 |
| Price TM et al. | Single- and multiple-dose pharmacokinetics of a low-dose oral contraceptive in women with chronic renal failure undergoing peritoneal dialysis. | 1993 | Am. J. Obstet. Gynecol. | pmid:8498419 |
| Anstee P and Kovacs GT | A prospective randomized study comparing the clinical effects of a norethisterone and a levonorgestrel containing low dose oestrogen oral contraceptive pills. | 1993 | Aust N Z J Obstet Gynaecol | pmid:8498949 |
| Pasqualini JR et al. | Plasma concentrations of ethynyl oestradiol and norethindrone after oral administration to women. | 1977 | J. Reprod. Fertil. | pmid:850209 |
| Nichols M et al. | Effect of four combined oral contraceptives on blood pressure in the pill-free interval. | 1993 | Contraception | pmid:8508666 |
| Köse K et al. | Contraceptive steroids increase erythrocyte lipid peroxidation in female rats. | 1993 | Contraception | pmid:8508671 |
| Taitel HF and Kafrissen ME | Norethindrone--a review of therapeutic applications. | 1995 Jul-Aug | Int J Fertil Menopausal Stud | pmid:8520623 |
| Broome M et al. | Enlarged follicles in women using oral contraceptives. | 1995 | Contraception | pmid:8521709 |
| Combs DW et al. | Nonsteroidal progesterone receptor ligands. 2. High-affinity ligands with selectivity for bone cell progesterone receptors. | 1995 | J. Med. Chem. | pmid:8523400 |
| Wemme H et al. | Effect of oestrogen/gestagen replacement therapy on liver enzymes in patients with Ullrich-Turner syndrome. | 1995 | Eur. J. Pediatr. | pmid:8529677 |
| Heiner JS et al. | Comparison of a gonadotropin-releasing hormone agonist and a low dose oral contraceptive given alone or together in the treatment of hirsutism. | 1995 | J. Clin. Endocrinol. Metab. | pmid:8530574 |
| Moutos D et al. | The effect of monophasic combinations of ethinyl estradiol and norethindrone on gonadotropins, androgens and sex hormone binding globulin: a randomized trial. | 1995 | Contraception | pmid:8536446 |
| Braselton WE et al. | Identification and measurement by gas chromatography-mass spectrometry of norethindrone and metabolites in human urine and blood. | 1977 | J. Steroid Biochem. | pmid:853745 |
| Eiken P and Kolthoff N | Compliance with long-term oral hormonal replacement therapy. | 1995 | Maturitas | pmid:8538490 |
| Schoonen WG et al. | Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: I. MCF-7 cell lines. | 1995 | J. Steroid Biochem. Mol. Biol. | pmid:8541240 |
| Schoonen WG et al. | Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines. | 1995 | J. Steroid Biochem. Mol. Biol. | pmid:8541241 |
| Gunston KD | Norethisterone enantate in the treatment of premenstrual syndrome. | 1995 | S. Afr. Med. J. | pmid:8545742 |
| Löw O et al. | Morphometric investigations on endocrine glands. V. Changes in the testes of Wistar rats after application of chlormadinone acetate and norethisterone acetate. | 1979 | Exp Pathol (Jena) | pmid:85556 |
| Manhem K et al. | Estrogen and progestagen modify the hemodynamic response to mental stress in young women. | 1996 | Acta Obstet Gynecol Scand | pmid:8560999 |
| DeCherney A | Bone-sparing properties of oral contraceptives. | 1996 | Am. J. Obstet. Gynecol. | pmid:8571999 |
| Wibbels T and Crews D | Steroid-induced sex determination at incubation temperatures producing mixed sex ratios in a turtle with TSD. | 1995 | Gen. Comp. Endocrinol. | pmid:8575659 |
| Ambrus JL et al. | Progestational agents and blood coagulation. VIII. Effect of low-dose, alternate-day, estrogen-progestin combinations on blood coagulation factors in man, with a special note on the effect of freezing of blood samples. | 1977 | Am. J. Obstet. Gynecol. | pmid:857675 |
| Tamaya T et al. | Contribution of functional groups of 19-nor-progestogens to binding to progesterone and estradiol-17beta receptors in rabbit uterus. | 1977 | Endocrinology | pmid:858280 |
| Niv Y and Henkin Y | Estrogen-progestin therapy and coronary heart disease in radiation-induced rectal telangiectases. | 1995 | J. Clin. Gastroenterol. | pmid:8583103 |
| Cerin A et al. | Adverse endometrial effects of long-cycle estrogen and progestogen replacement therapy. The Scandinavian LongCycle Study Group. | 1996 | N. Engl. J. Med. | pmid:8592546 |
| Dhillon VS and Dhillon IK | Genotoxicity evaluation of norethisterone acetate. | 1996 | Mutat. Res. | pmid:8596541 |
| Sapire KE and Dommisse J | Injectable contraception and lactation. | 1995 | S. Afr. Med. J. | pmid:8600593 |
| van den Brûle FA et al. | Absence of antisteroid antibodies in oral contraceptive users presenting with vascular events. | 1995 | Contraception | pmid:8605782 |
| Aune B et al. | Hormone replacement therapy reduces the reactivity of monocytes and platelets in whole blood--a beneficial effect on atherogenesis and thrombus formation? | 1995 | Am. J. Obstet. Gynecol. | pmid:8610768 |
| Brügmann E et al. | Studies on liver function under the influence of oral contraceptives. | 1979 Mar-Apr | Int J Gynaecol Obstet | pmid:86470 |
| Bryner RW et al. | Effect of low dose oral contraceptives on exercise performance. | 1996 | Br J Sports Med | pmid:8665116 |
| Seewald HJ et al. | [Results of high dosage progesterone therapy in carcinoma corporis uteri]. | 1977 | Zentralbl Gynakol | pmid:868363 |
| Takada J et al. | Pretreatment with low doses of norethindrone potentiates the osteogenic effects of fluoride on human osteosarcoma cells. | 1995 | J. Bone Miner. Res. | pmid:8686507 |
| Chatten LG et al. | Polarographic study of certain progestogens and their determination in oral contraceptive tablets by differential pulse polarography. | 1977 | Analyst | pmid:869208 |
| de Gennes JL et al. | [Ischemic cardiovascular accidents during treatment with progestins alone. Apropos of 3 cases]. | 1979 Jan-Feb | Ann. Endocrinol. (Paris) | pmid:87143 |