| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
Total
3
Norethindrone
Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.
Cross Reference
Introduction
To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Norethindrone?
Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Norethindrone
PubChem Associated disorders and diseases
What pathways are associated with Norethindrone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Norethindrone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Norethindrone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Norethindrone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Norethindrone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Norethindrone?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Norethindrone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hasegawa S et al. | Thromboembolic adverse event study of combined estrogen-progestin preparations using Japanese Adverse Drug Event Report database. | 2017 | PLoS ONE | pmid:28732067 |
| McGlinchey EM et al. | Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine-Dependent Manner to Drive Cued Reinstatement of Cocaine Seeking. | 2016 | J. Neurosci. | pmid:27535915 |
| Ganderton C et al. | Does menopausal hormone therapy (MHT), exercise or a combination of both, improve pain and function in post-menopausal women with greater trochanteric pain syndrome (GTPS)? A randomised controlled trial. | 2016 | BMC Womens Health | pmid:27312538 |
| Brynhildsen J | [Not Available]. | 2016 | Lakartidningen | pmid:27299335 |
| Liu X et al. | Probing Steroidal Substrate Specificity of Cytochrome P450 BM3 Variants. | 2016 | Molecules | pmid:27294908 |
| Soliman AM et al. | Analysis of Adherence, Persistence, and Surgery Among Endometriosis Patients Treated with Leuprolide Acetate Plus Norethindrone Acetate Add-Back Therapy. | 2016 | J Manag Care Spec Pharm | pmid:27123918 |
| Hofmeyr GJ et al. | Effects of the copper intrauterine device versus injectable progestin contraception on pregnancy rates and method discontinuation among women attending termination of pregnancy services in South Africa: a pragmatic randomized controlled trial. | 2016 | Reprod Health | pmid:27091008 |
| Maybin JA and Critchley HO | Medical management of heavy menstrual bleeding. | 2016 | Womens Health (Lond) | pmid:26695687 |
| Román M et al. | Postmenopausal hormone therapy and the risk of breast cancer in Norway. | 2016 | Int. J. Cancer | pmid:26289549 |
| Cano-Nicolau J et al. | Several synthetic progestins disrupt the glial cell specific-brain aromatase expression in developing zebra fish. | 2016 | Toxicol. Appl. Pharmacol. | pmid:27245768 |
| Fan F et al. | Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs. | 2015 | Toxicol. Sci. | pmid:25752796 |
| Callahan R et al. | Ectopic pregnancy with use of progestin-only injectables and contraceptive implants: a systematic review. | 2015 | Contraception | pmid:26363431 |
| Agarwal SK and Foster WG | Reduction in Endometrioma Size with Three Months of Aromatase Inhibition and Progestin Add-Back. | 2015 | Biomed Res Int | pmid:26247030 |
| DiVasta AD et al. | Hormonal Add-Back Therapy for Females Treated With Gonadotropin-Releasing Hormone Agonist for Endometriosis: A Randomized Controlled Trial. | 2015 | Obstet Gynecol | pmid:26181088 |
| Noguchi LM et al. | Risk of HIV-1 acquisition among women who use diff erent types of injectable progestin contraception in South Africa: a prospective cohort study. | 2015 | Lancet HIV | pmid:26155597 |
| Al Abdulhai SA et al. | Bleeding and thrombosis in a patient with primary antiphospholipid syndrome using norethisterone: a case report. | 2015 | J Med Case Rep | pmid:25895835 |
| Lakryc EM et al. | What is the influence of hormone therapy on homocysteine and crp levels in postmenopausal women? | 2015 | Clinics (Sao Paulo) | pmid:25789519 |
| Stachowiak G et al. | Effect of transdermal hormone therapy on platelet haemostasis in menopausal women. | 2015 | Ann Agric Environ Med | pmid:25780849 |
| Morrison CS et al. | Hormonal contraception and the risk of HIV acquisition: an individual participant data meta-analysis. | 2015 | PLoS Med. | pmid:25612136 |
| Zomerdijk IM et al. | Dispensing of potentially teratogenic drugs before conception and during pregnancy: a population-based study. | 2015 | BJOG | pmid:25316196 |
| Atrio J et al. | The effect of protease inhibitors on the cervical mucus of HIV-positive women taking norethindrone contraception. | 2015 | Eur J Contracept Reprod Health Care | pmid:25285572 |
| DuBois BN et al. | Increased exposure of norethindrone in HIV+ women treated with ritonavir-boosted atazanavir therapy. | 2015 | Contraception | pmid:25245190 |
| Posadzy-Malaczynska A et al. | Hemodynamic and metabolic effects of estrogen plus progestin therapy in hypertensive postmenopausal women treated with an ACE-inhibitor or a diuretic. | 2015 | Clin Res Cardiol | pmid:25216597 |
| Jeffery J et al. | Norethisterone interference in testosterone assays. | 2014 | Ann. Clin. Biochem. | pmid:24265092 |
| Crauwels HM et al. | Lack of an effect of rilpivirine on the pharmacokinetics of ethinylestradiol and norethindrone in healthy volunteers. | 2014 | Int J Clin Pharmacol Ther | pmid:24161160 |
| Zhang X et al. | Assessment of disease-drug-drug interaction between single-dose tocilizumab and oral contraceptives in women with active rheumatoid arthritis. | 2014 | Int J Clin Pharmacol Ther | pmid:24161161 |
| Reyes M et al. | Effects of ponesimod, a selective S1P1 receptor modulator, on the pharmacokinetics of a hormonal combination contraceptive. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24362488 |
| Gusenleitner D et al. | Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action. | 2014 | PLoS ONE | pmid:25058030 |
| Huang R et al. | Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway. | 2014 | Sci Rep | pmid:25012808 |
| Sweeney EE et al. | Molecular modulation of estrogen-induced apoptosis by synthetic progestins in hormone replacement therapy: an insight into the women's health initiative study. | 2014 | Cancer Res. | pmid:25304262 |
| Polis CB et al. | Hormonal contraceptive methods and risk of HIV acquisition in women: a systematic review of epidemiological evidence. | 2014 | Contraception | pmid:25183264 |
| Borghese B et al. | [Recurrence of pain after surgery for deeply infiltrating endometriosis: How does it happen? How to manage?]. | 2014 | J Gynecol Obstet Biol Reprod (Paris) | pmid:23265672 |
| Blanchard K et al. | Clinicians' perceptions and provision of hormonal contraceptives for HIV-positive and at-risk women in Southern Africa: an original research article. | 2014 | Contraception | pmid:24924260 |
| Freudenberger T et al. | Synthetic gestagens exert differential effects on arterial thrombosis and aortic gene expression in ovariectomized apolipoprotein E-deficient mice. | 2014 | Br. J. Pharmacol. | pmid:24923668 |
| Govender Y et al. | The injectable-only contraceptive medroxyprogesterone acetate, unlike norethisterone acetate and progesterone, regulates inflammatory genes in endocervical cells via the glucocorticoid receptor. | 2014 | PLoS ONE | pmid:24840644 |
| Huijbregts RP et al. | Effect of progestins on immunity: medroxyprogesterone but not norethisterone or levonorgestrel suppresses the function of T cells and pDCs. | 2014 | Contraception | pmid:24674041 |
| Atrio J et al. | Effect of protease inhibitors on steady-state pharmacokinetics of oral norethindrone contraception in HIV-infected women. | 2014 | J. Acquir. Immune Defic. Syndr. | pmid:24025339 |
| Cooney R and Hayward P | Highlights from the 21st CROI. | 2014 | Lancet Infect Dis | pmid:24800301 |
| Donnez J et al. | Long-term treatment of uterine fibroids with ulipristal acetate ☆. | 2014 | Fertil. Steril. | pmid:24630081 |
| Caserta D et al. | A 29-year-old woman with complex atypical hyperplasia and polycystic ovary syndrome: a challenging issue. | 2014 | Eur. J. Gynaecol. Oncol. | pmid:24654474 |
| Cates W | Research on hormonal contraception and HIV. | 2014 | Lancet | pmid:24461116 |
| Gollub EL and Stein Z | Research on hormonal contraception and HIV. | 2014 | Lancet | pmid:24461117 |
| Redd AD | Research on hormonal contraception and HIV. | 2014 | Lancet | pmid:24461118 |
| Ralph L et al. | Research on hormonal contraception and HIV - Authors' reply. | 2014 | Lancet | pmid:24461119 |
| Basavaraja N et al. | Norethindrone-induced masculinization and progeny testing in guppy, Poecilia reticulata (Peters 1859). | 2014 | Indian J. Exp. Biol. | pmid:24669666 |
| Santos M et al. | Retrospective review of norethindrone use in adolescents. | 2014 | J Pediatr Adolesc Gynecol | pmid:24315714 |
| Ferrero S et al. | Norethisterone acetate versus norethisterone acetate combined with letrozole for the treatment of ovarian endometriotic cysts: a patient preference study. | 2014 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:24388845 |
| Kogan P and Wald M | Male contraception: history and development. | 2014 | Urol. Clin. North Am. | pmid:24286773 |
| Labos G et al. | Efficacy and safety of DT56a compared to hormone therapy in Greek post-menopausal women. | 2013 Jul-Aug | J. Endocrinol. Invest. | pmid:23563111 |
| Koskela-Niska V et al. | Ovarian cancer risk in postmenopausal women using estradiol-progestin therapy - a nationwide study. | 2013 | Climacteric | pmid:22640598 |
| Brosnan JF et al. | Norethisterone acetate alters coagulation gene expression in vitro in human cell culture. | 2013 | Thromb. Res. | pmid:22999413 |
| Archer DF et al. | Norethindrone acetate 1.0 milligram and ethinyl estradiol 10 micrograms as an ultra low-dose oral contraceptive. | 2013 | Obstet Gynecol | pmid:23921878 |
| Gutsche JT et al. | Treatment of ventricular assist-device-associated gastrointestinal bleeding with hormonal therapy. | 2013 | J. Cardiothorac. Vasc. Anesth. | pmid:24054188 |
| Wistuba J et al. | Experimental endocrine manipulation by contraceptive regimen in the male marmoset (Callithrix jacchus). | 2013 | Reproduction | pmid:23431271 |
| Tomasicchio M et al. | The progestin-only contraceptive medroxyprogesterone acetate, but not norethisterone acetate, enhances HIV-1 Vpr-mediated apoptosis in human CD4+ T cells through the glucocorticoid receptor. | 2013 | PLoS ONE | pmid:23658782 |
| Polisseni AF et al. | Effects of a continuous-combined regimen of low-dose hormone therapy (oestradiol and norethindrone acetate) and tibolone on the quality of life in symptomatic postmenopausal women: a double-blind, randomised study. | 2013 | Maturitas | pmid:23201326 |
| Schneck H et al. | Membrane-receptor initiated proliferative effects of dienogest in human breast cancer cells. | 2013 | Gynecol. Endocrinol. | pmid:23116217 |
| Połać I et al. | Coagulation and fibrynolitic parameters in women and the effects of hormone therapy; comparison of transdermal and oral administration. | 2013 | Gynecol. Endocrinol. | pmid:23116237 |
| Chen FP et al. | Effects of estradiol and progestogens on human breast cells: regulation of sex steroid receptors. | 2013 | Taiwan J Obstet Gynecol | pmid:24075375 |
| Minami T et al. | Antiproliferative and apoptotic effects of norethisterone on endometriotic stromal cells in vitro. | 2013 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:22964137 |
| Crean CS et al. | The effect of ezogabine on the pharmacokinetics of an oral contraceptive agent. | 2013 | Int J Clin Pharmacol Ther | pmid:24040852 |
| Price T | Progesterone receptor membrane component 1: is metabolism integral to its function and what other steroids are involved? | 2013 | Menopause | pmid:23511707 |
| Stanczyk FZ and Winer SA | Effect of hormone therapy on breast epithelial cell proliferation. | 2013 | Menopause | pmid:23615638 |
| Cheng G et al. | Effects of short-term estradiol and norethindrone acetate treatment on the breasts of normal postmenopausal women. | 2013 | Menopause | pmid:23615640 |
| Neubauer H et al. | Overexpression of progesterone receptor membrane component 1: possible mechanism for increased breast cancer risk with norethisterone in hormone therapy. | 2013 | Menopause | pmid:23615641 |
| Demeestere I et al. | Gonadotropin-releasing hormone agonist for the prevention of chemotherapy-induced ovarian failure in patients with lymphoma: 1-year follow-up of a prospective randomized trial. | 2013 | J. Clin. Oncol. | pmid:23129737 |
| Vercellini P et al. | Surgical versus low-dose progestin treatment for endometriosis-associated severe deep dyspareunia II: effect on sexual functioning, psychological status and health-related quality of life. | 2013 | Hum. Reprod. | pmid:23442755 |
| Africander D et al. | Investigating the anti-mineralocorticoid properties of synthetic progestins used in hormone therapy. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23473756 |
| Ralph LJ et al. | Next steps for research on hormonal contraception and HIV. | 2013 | Lancet | pmid:23810224 |
| Zhou J et al. | Medroxyprogesterone acetate-driven increase in breast cancer risk might be mediated via cross-talk with growth factors in the presence of progesterone receptor membrane component-1. | 2013 | Maturitas | pmid:23856385 |
| Roach RE et al. | The risk of venous thrombosis in women over 50 years old using oral contraception or postmenopausal hormone therapy. | 2013 | J. Thromb. Haemost. | pmid:23136837 |
| Juvkam KH and Gudim HB | [Drug induced displacement of menstruation]. | 2013 | Tidsskr. Nor. Laegeforen. | pmid:23344601 |
| Buccellato E et al. | Possible occurrence of paraesthesia in patients taking norethisterone: an analysis on the WHO Global Individual Case Reports database (VigiBase). | 2013 | Expert Opin Drug Saf | pmid:23701188 |
| Manassiev N et al. | Effects of tibolone or continuous combined oestradiol/norethisterone acetate on glucose and insulin metabolism. | 2013 | Clin. Endocrinol. (Oxf) | pmid:22775481 |
| Merviel P et al. | [Interest of selective progesterone receptor modulators in endometriosis]. | 2013 | Gynecol Obstet Fertil | pmid:23972920 |
| Abdul-Hadi RA et al. | The effectiveness of community based distribution of injectable contraceptives using community health extension workers in Gombe State, Northern Nigeria. | 2013 | Afr J Reprod Health | pmid:24069754 |
| Fels H et al. | Comparison of serum and cervical mucus hormone levels during hormone-free interval of 24/4 vs. 21/7 combined oral contraceptives. | 2013 | Contraception | pmid:23352800 |
| Polis CB and Curtis KM | Use of hormonal contraceptives and HIV acquisition in women: a systematic review of the epidemiological evidence. | 2013 | Lancet Infect Dis | pmid:23871397 |
| Biddle ST et al. | Metabolism of norethisterone in the greyhound. | 2013 | Rapid Commun. Mass Spectrom. | pmid:24019188 |
| Ferrero S et al. | Changes in the size of rectovaginal endometriotic nodules infiltrating the rectum during hormonal therapies. | 2013 | Arch. Gynecol. Obstet. | pmid:23053314 |
| Mackay L et al. | Hormone replacement therapy for women with type 1 diabetes mellitus. | 2013 | Cochrane Database Syst Rev | pmid:23744560 |
| LoRusso PM et al. | Co-administration of vismodegib with rosiglitazone or combined oral contraceptive in patients with locally advanced or metastatic solid tumors: a pharmacokinetic assessment of drug-drug interaction potential. | 2013 | Cancer Chemother. Pharmacol. | pmid:23064958 |
| Jonusiene G et al. | Sexual function, mood and menopause symptoms in Lithuanian postmenopausal women. | 2013 | Climacteric | pmid:22845491 |
| Adeyemi AS and Adekanle DA | Progestogen-only injectable contraceptive: experience of women in Osogbo, southwestern Nigeria. | 2012 Jan-Mar | Ann Afr Med | pmid:22199044 |
| Naqaish T et al. | Patient satisfaction for levonorgestrel intrauterine system and norethisterone for treatment of dysfunctional uterine bleeding. | 2012 Jan-Mar | J Ayub Med Coll Abbottabad | pmid:23855088 |
| Rea V et al. | Active site substitution A82W improves the regioselectivity of steroid hydroxylation by cytochrome P450 BM3 mutants as rationalized by spin relaxation nuclear magnetic resonance studies. | 2012 | Biochemistry | pmid:22208729 |
| Dahm AE et al. | A microarray study on the effect of four hormone therapy regimens on gene transcription in whole blood from healthy postmenopausal women. | 2012 | Thromb. Res. | pmid:22217510 |
| Lopes I et al. | Toxicity and genotoxicity of organic and inorganic nanoparticles to the bacteria Vibrio fischeri and Salmonella typhimurium. | 2012 | Ecotoxicology | pmid:22314390 |
| Vercellini P et al. | Surgical versus medical treatment for endometriosis-associated severe deep dyspareunia: I. Effect on pain during intercourse and patient satisfaction. | 2012 | Hum. Reprod. | pmid:22926841 |
| Morrison CS et al. | Hormonal contraception and the risk of HIV acquisition among women in South Africa. | 2012 | AIDS | pmid:22156973 |
| Queenan JT | Exploring contraceptive options for breastfeeding mothers. | 2012 | Obstet Gynecol | pmid:22183205 |
| Kaore SN et al. | Novel actions of progesterone: what we know today and what will be the scenario in the future? | 2012 | J. Pharm. Pharmacol. | pmid:22775208 |
| Chawla B et al. | A unique modification of the eukaryotic initiation factor 5A shows the presence of the complete hypusine pathway in Leishmania donovani. | 2012 | PLoS ONE | pmid:22438895 |
| Castilho CS et al. | Genetic structure and conservation of Mountain Lions in the South-Brazilian Atlantic Rain Forest. | 2012 | Genet. Mol. Biol. | pmid:22481876 |
| Kumar V et al. | Bioremediation of agro-based pulp mill effluent by microbial consortium comprising autochthonous bacteria. | 2012 | ScientificWorldJournal | pmid:22448126 |
| Gümüş BA and Neubert E | New taxa of terrestrial molluscs from Turkey (Gastropoda, Pristilomatidae, Enidae, Hygromiidae, Helicidae). | 2012 | Zookeys | pmid:22423194 |
| Chen X et al. | Liposomes prolong the therapeutic effect of anti-asthmatic medication via pulmonary delivery. | 2012 | Int J Nanomedicine | pmid:22412300 |
| Tenne SJ and Schwaneberg U | First insights on organic cosolvent effects on FhuA wildtype and FhuA Δ1-159. | 2012 | Int J Mol Sci | pmid:22408464 |
| Puli MR and Raghavendra AS | Pyrabactin, an ABA agonist, induced stomatal closure and changes in signalling components of guard cells in abaxial epidermis of Pisum sativum. | 2012 | J. Exp. Bot. | pmid:22131162 |
| Kraut R et al. | Fluorescence correlation methods for imaging cellular behavior of sphingolipid-interacting probes. | 2012 | Methods Cell Biol. | pmid:22325612 |