Norethindrone

Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.

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Introduction

To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Norethindrone?

Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Norethindrone

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Norethindrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Norethindrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Norethindrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Norethindrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Norethindrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Norethindrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Norethindrone

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Authors Title Published Journal PubMed Link
Mulder TP et al. Effects of hormone replacement therapy on plasma glutathione S-transferase A1-1 concentrations in healthy postmenopausal women. 1998 Clin. Chem. pmid:9510879
Leach M et al. Norethisterone therapy for bleeding due to gastrointestinal telangiectases in Glanzmann's thrombasthenia. 1998 Br. J. Haematol. pmid:9504647
Sinofsky FE and Pasquale SA The effect of fluconazole on circulating ethinyl estradiol levels in women taking oral contraceptives. 1998 Am. J. Obstet. Gynecol. pmid:9500490
el-Heneidy AR et al. The effect of an oral contraceptive on the pulmonary functions. 1976 Contraception pmid:949891
Kuhnz W et al. In vivo conversion of norethisterone and norethisterone acetate to ethinyl etradiol in postmenopausal women. 1997 Contraception pmid:9494772
Luckas MJ et al. The effect of progestagens on the carotid artery pulsatility index in postmenopausal women on oestrogen replacement therapy. 1998 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:9481579
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Norethin: lower cost can improve OC compliance. 1997 Adv Nurse Pract pmid:9460009
Hyder SM et al. Progestin regulation of vascular endothelial growth factor in human breast cancer cells. 1998 Cancer Res. pmid:9458078
Andersen RN et al. Response of the binding capacity of plasma testosterone-estradiol-binding globulin to norethindrone, 2 mg., and mestranol, 0.1 mg., in polycystic ovarian disease. 1976 Am. J. Obstet. Gynecol. pmid:944533
Dickey RP et al. Estrogen potencies of three new low-dose oral contraceptives. 1976 Am. J. Obstet. Gynecol. pmid:941952
Shetty G et al. Use of norethisterone and estradiol in mini doses as a contraceptive in the male. Efficacy studies in the adult male bonnet monkey (Macaca radiata). 1997 Contraception pmid:9408708
Weisberg E et al. Effect of different insertion regimens on side effects with a combination contraceptive vaginal ring. 1997 Contraception pmid:9408704
Comparative study of the effects of two once-a-month injectable steroidal contraceptives (Mesigyna and Cyclofem) on lipid and lipoprotein metabolism. United Nations Development Programme/United Nations Population Fund/World Health Organization/World Bank, Special Programme of Research, Development and Research Training in Human Reproduction. 1997 Contraception pmid:9408700
De Aguilar MA et al. Current status of injectable hormonal contraception, with special reference to the monthly method. 1997 Adv Contracept pmid:9404550
Beier S et al. The progestational activity of different gestagens used for human contraception in the beagle bitch. 1979 Contraception pmid:94000
Mc Manus J et al. The effect of hormone replacement therapy on the oxidation of low density lipoprotein in postmenopausal women. 1997 Atherosclerosis pmid:9395275
Ulrich LG et al. Quality of life and patient preference for sequential versus continuous combined HRT: the UK Kliofem multicenter study experience. UK Continuous Combined HRT Study Investigators. 1997 Int J Gynaecol Obstet pmid:9386211
Marcucci F et al. Effect of estrogen-progestin combinations on the hepatic microsomal metabolism of mestranol. 1976 Biochem. Pharmacol. pmid:938556