| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
Total
3
Norethindrone
Norethindrone is a lipid of Sterol Lipids (ST) class. Norethindrone is associated with abnormalities such as Endometriosis, site unspecified, Wiskott-Aldrich Syndrome and Estrogenic effect. The involved functions are known as Hemorrhage, Phosphorylation, Apoptosis, DNA Repair and Cell Cycle. Norethindrone often locates in Blood, Back, Body tissue, Nucleolar and Human tissue. The associated genes with Norethindrone are MMP gene, NR3C1 gene and Genes, Reporter. The related lipids are Steroids, 4,17 beta-dihydroxy-4-androstene-3-one, 4-estren-3,17-diol and Estranes.
Cross Reference
Introduction
To understand associated biological information of Norethindrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Norethindrone?
Norethindrone is suspected in Endometriosis, site unspecified, Estrogenic effect and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Norethindrone
PubChem Associated disorders and diseases
What pathways are associated with Norethindrone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Norethindrone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Norethindrone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Norethindrone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Norethindrone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Norethindrone?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Norethindrone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lópezde Alda MJ and Barceló D | Use of solid-phase extraction in various of its modalities for sample preparation in the determination of estrogens and progestogens in sediment and water. | 2001 | J Chromatogr A | pmid:11771833 |
| Nash HA and Sederholt D | Assessment of the toxicity of delivery systems for injectable contraceptives. | 1975 | J. Steroid Biochem. | pmid:1177434 |
| Morris SE and Cameron EH | Radioimmunoassay system for norethisterone using 3H- and 125I-labelled radioligands. | 1975 | J. Steroid Biochem. | pmid:1177442 |
| Warren RJ and Fotherby K | Iodine labelled ligands in the radioimmunoassay of synthetic progestins. | 1975 | J. Steroid Biochem. | pmid:1177443 |
| Zhang S et al. | [The efficacy and safety of domestic luteinizing hormone-releasing hormone analogue and low-dose norethindrone "add-back" therapy in the treatment of endometriosis]. | 2000 | Zhonghua Fu Chan Ke Za Zhi | pmid:11776204 |
| Beksinska ME et al. | Temporary discontinuation: a compliance issue in injectable users. | 2001 | Contraception | pmid:11777492 |
| pmid:11779584 | ||||
| Johnson JV et al. | Postmenopausal uterine bleeding profiles with two forms of continuous combined hormone replacement therapy. | 2002 Jan-Feb | Menopause | pmid:11791082 |
| Niskanen L et al. | Does postmenopausal hormone replacement therapy affect cardiac autonomic regulation in osteoporotic women? | 2002 Jan-Feb | Menopause | pmid:11791086 |
| Mueck AO et al. | [Effect of tibolone on vascular markers of human female coronary arteries - comparison with estradiol/norethisterone]. | 2001 | Zentralbl Gynakol | pmid:11797164 |
| Perera M et al. | Hormone replacement therapy can augment vascular relaxation in post-menopausal women with type 2 diabetes. | 2002 | Hum. Reprod. | pmid:11821303 |
| Schwartz JI et al. | Effect of rofecoxib on the pharmacokinetics of chronically administered oral contraceptives in healthy female volunteers. | 2002 | J Clin Pharmacol | pmid:11831545 |
| Loh FH et al. | The efficacy of two dosages of a continuous combined hormone replacement regimen. | 2002 | Maturitas | pmid:11836043 |
| Kamischke A et al. | An effective hormonal male contraceptive using testosterone undecanoate with oral or injectable norethisterone preparations. | 2002 | J. Clin. Endocrinol. Metab. | pmid:11836281 |
| pmid:11838560 | ||||
| pmid:11846566 | ||||
| Mousa HA and Thong J | Omental pregnancy in a woman taking the progestogen-only pill. | 2001 | Acta Obstet Gynecol Scand | pmid:11846713 |
| Ekhato IV et al. | Norethindrone acetate (NA) and ethinyl estradiol (EE) related oxidative transformation products in stability samples of formulated drug product: synthesis of authentic references. | 2002 | Steroids | pmid:11856540 |
| pmid:11870137 | ||||
| Verhoeven CH et al. | Identification of the human P450 enzymes involved in the in vitro metabolism of the synthetic steroidal hormones Org 4060 and Org 30659. | 2002 | Xenobiotica | pmid:11871398 |
| Brynhildsen J and Hammar M | Low dose transdermal estradiol/norethisterone acetate treatment over 2 years does not cause endometrial proliferation in postmenopausal women. | 2002 Mar-Apr | Menopause | pmid:11875333 |
| Teede HJ et al. | A placebo-controlled trial of long-term oral combined continuous hormone replacement therapy in postmenopausal women: effects on arterial compliance and endothelial function. | 2001 | Clin. Endocrinol. (Oxf) | pmid:11894980 |
| Guzic-Salobir B et al. | Combined hormone replacement therapy improves endothelial function in healthy postmenopausal women. | 2001 | J. Intern. Med. | pmid:11902819 |
| Brewer M et al. | Rhesus macaque model for ovarian cancer chemoprevention. | 2001 | Comp. Med. | pmid:11924802 |
| pmid:11925375 | ||||
| Ghoneim SM et al. | The effect of an oral contraceptive on acid-base balance, blood gases and electrolytes. | 1975 | Contraception | pmid:1192729 |
| Pasquale SA and Yuliano E | Clinical results with a new low dose oral contraceptive utilizing norethindrone/ethinyl estradiol. | 1975 | Contraception | pmid:1192736 |
| Kärkkäinen J et al. | Steroid methoximes II: Antifertility activity of norethisterone-3-methoxime in the rat. | 1975 | Contraception | pmid:1192738 |
| Gräf KJ et al. | The progestogenic potencies of different progestogens in the beagle bitch. | 1975 | Contraception | pmid:1192740 |
| Srivastava UK and Laumas KR | Long-term contraception by steroid-releasing implants. IV. Biological effectiveness of norethindrone acetate (ENTA) implants in rats and rabbits. | 1975 | Contraception | pmid:1192742 |
| Bjarnason NH et al. | Number of years since menopause: spontaneous bone loss is dependent but response to hormone replacement therapy is independent. | 2002 | Bone | pmid:11934658 |
| Chien YW et al. | Controlled drug release from polymeric delivery devices. III: In vitro-in vivo correlation for intravaginal release of ethynodiol diacetate from silicone devices in rabbits. | 1975 | J Pharm Sci | pmid:1195107 |
| Pasapera AM et al. | Transactivation of progestin- and estrogen-responsive promoters by 19-nor progestins in African Green Monkey Kidney CV1 cells. | 2001 | Endocrine | pmid:11954666 |
| Prasad KV et al. | The rabbit as an animal model to study pharmacokinetics of norethindrone in women. | 1979 | Contraception | pmid:119608 |
| Spellacy WN et al. | Effects of norethindrone on carbohydrate and lipid metabolism. | 1975 | Obstet Gynecol | pmid:1196559 |
| Lundström E et al. | Effects of tibolone and continuous combined hormone replacement therapy on mammographic breast density. | 2002 | Am. J. Obstet. Gynecol. | pmid:11967497 |
| Surrey ES and Hornstein MD | Prolonged GnRH agonist and add-back therapy for symptomatic endometriosis: long-term follow-up. | 2002 | Obstet Gynecol | pmid:11978277 |
| pmid:11980386 | ||||
| Rolf C et al. | Pharmacokinetics of a new transdermal testosterone gel in gonadotrophin-suppressed normal men. | 2002 | Eur. J. Endocrinol. | pmid:11980623 |
| Mildvan D et al. | Pharmacokinetic interaction between nevirapine and ethinyl estradiol/norethindrone when administered concurrently to HIV-infected women. | 2002 | J. Acquir. Immune Defic. Syndr. | pmid:11981363 |
| Skouby SO et al. | Hormone replacement therapy: estrogen and progestin effects on plasma C-reactive protein concentrations. | 2002 | Am. J. Obstet. Gynecol. | pmid:12015523 |
| Lidor AL et al. | Effect of raloxifene on the ovarian circulation in women after menopause. | 2002 | Am. J. Obstet. Gynecol. | pmid:12015525 |
| Hodgson H | Hormonal therapy for gastrointestinal angiodysplasia. | 2002 | Lancet | pmid:12020519 |
| Nerbrand C et al. | Effects of a lipid lowering fibrate and hormone replacement therapy on serum lipids and lipoproteins in overweight postmenopausal women with elevated triglycerides. | 2002 | Maturitas | pmid:12020980 |
| Christodoulacos G et al. | Transvaginal sonographic monitoring of the uterine effects of raloxifene and a continuous combined replacement therapy in postmenopausal women. | 2002 | Maturitas | pmid:12020983 |
| Rolf C et al. | Interpersonal testosterone transfer after topical application of a newly developed testosterone gel preparation. | 2002 | Clin. Endocrinol. (Oxf) | pmid:12030915 |
| Campagnoli C et al. | Positive effects on cardiovascular and breast metabolic markers of oral estradiol and dydrogesterone in comparison with transdermal estradiol and norethisterone acetate. | 2002 | Maturitas | pmid:12034517 |
| Peter St et al. | [Ultrastructure of the prolactin cells of the pituitary gland of female rats after stimulation with norethisterone enanthate]. | 1975 | Bull Assoc Anat (Nancy) | pmid:1203559 |
| Croxatto HB et al. | Clinical assessment of subdermal implants of megestrol acetate, d-norgestrel, and norethindrone as a longterm contraceptive in women. | 1975 | Contraception | pmid:1204349 |
| Grinspoon S et al. | Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa. | 2002 | J. Clin. Endocrinol. Metab. | pmid:12050268 |