MeSH term | MeSH ID | Detail |
---|---|---|
Lung Neoplasms | D008175 | 171 associated lipids |
Carcinoma, Small Cell | D018288 | 21 associated lipids |
Cachexia | D002100 | 21 associated lipids |
Megestrol acetate is a lipid of Sterol Lipids (ST) class. Megestrol acetate is associated with abnormalities such as Anorexia, Malnutrition, HIV Infections, Thrombocytopenia and Exanthema. The involved functions are known as Bleeding of vagina, Agent, Cell Survival, Cytopenia and Regulation. The associated genes with Megestrol acetate are Genome. The related lipids are Steroids. The related experimental models are Xenograft Model.
To understand associated biological information of Megestrol acetate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Megestrol acetate is suspected in Anorexia, Secondary hypocortisolism, Wasting, Malnutrition, HIV Infections, Thrombocytopenia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Megestrol acetate
MeSH term | MeSH ID | Detail |
---|---|---|
Lung Neoplasms | D008175 | 171 associated lipids |
Carcinoma, Small Cell | D018288 | 21 associated lipids |
Cachexia | D002100 | 21 associated lipids |
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'The effect of megestrol acetate on growth of HepG2 cells in vitro and in vivo.' (Zhang K and Chow PK, 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Falcone F et al. | Fertility preserving treatment with hysteroscopic resection followed by progestin therapy in young women with early endometrial cancer. | 2017 | J Gynecol Oncol | pmid:27670256 |
Gungor T et al. | Clinicopathologic characteristics and treatment features of women with the incidental diagnosis of endometrial adenocarcinoma during infertility follow-up in Ankara, Turkey. | 2016 | Taiwan J Obstet Gynecol | pmid:27343306 |
Nanjappa S et al. | Pharmacy Report: Megestrol Acetate-Induced Adrenal Insufficiency. | 2016 | Cancer Control | pmid:27218795 |
Myers AP et al. | Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study. | 2016 | Gynecol. Oncol. | pmid:27016228 |
Lachowicz M et al. | New Biopolymer Nanoparticles Improve the Solubility of Lipophilic Megestrol Acetate. | 2016 | Molecules | pmid:26861275 |
Han HS et al. | A Prospective Multicenter Study Evaluating Secondary Adrenal Suppression After Antiemetic Dexamethasone Therapy in Cancer Patients Receiving Chemotherapy: A Korean South West Oncology Group Study. | 2015 | Oncologist | pmid:26463869 |
Ha ES et al. | Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process. | 2015 | Drug Des Devel Ther | pmid:26345723 |
Zaza KJ et al. | Vulvar extrauterine endometrial stromal sarcoma: A case report and literature review. | 2015 | Hematol Oncol Stem Cell Ther | pmid:25585306 |
Fan F et al. | Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs. | 2015 | Toxicol. Sci. | pmid:25752796 |
Kanat O | Management of cancer cachexia (reply). | 2014 Jan-Feb | Tumori | pmid:24675504 |