Megestrol acetate

Megestrol acetate is a lipid of Sterol Lipids (ST) class. Megestrol acetate is associated with abnormalities such as Anorexia, Malnutrition, HIV Infections, Thrombocytopenia and Exanthema. The involved functions are known as Bleeding of vagina, Agent, Cell Survival, Cytopenia and Regulation. The associated genes with Megestrol acetate are Genome. The related lipids are Steroids. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of Megestrol acetate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Megestrol acetate?

Megestrol acetate is suspected in Anorexia, Secondary hypocortisolism, Wasting, Malnutrition, HIV Infections, Thrombocytopenia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Megestrol acetate

MeSH term MeSH ID Detail
Lung Neoplasms D008175 171 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Cachexia D002100 21 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Megestrol acetate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Megestrol acetate?

There are no associated biomedical information in the current reference collection.

What functions are associated with Megestrol acetate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Megestrol acetate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Megestrol acetate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Megestrol acetate?

Xenograft Model

Xenograft Model are used in the study 'The effect of megestrol acetate on growth of HepG2 cells in vitro and in vivo.' (Zhang K and Chow PK, 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Megestrol acetate

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Authors Title Published Journal PubMed Link
Falcone F et al. Fertility preserving treatment with hysteroscopic resection followed by progestin therapy in young women with early endometrial cancer. 2017 J Gynecol Oncol pmid:27670256
Gungor T et al. Clinicopathologic characteristics and treatment features of women with the incidental diagnosis of endometrial adenocarcinoma during infertility follow-up in Ankara, Turkey. 2016 Taiwan J Obstet Gynecol pmid:27343306
Nanjappa S et al. Pharmacy Report: Megestrol Acetate-Induced Adrenal Insufficiency. 2016 Cancer Control pmid:27218795
Myers AP et al. Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study. 2016 Gynecol. Oncol. pmid:27016228
Lachowicz M et al. New Biopolymer Nanoparticles Improve the Solubility of Lipophilic Megestrol Acetate. 2016 Molecules pmid:26861275
Han HS et al. A Prospective Multicenter Study Evaluating Secondary Adrenal Suppression After Antiemetic Dexamethasone Therapy in Cancer Patients Receiving Chemotherapy: A Korean South West Oncology Group Study. 2015 Oncologist pmid:26463869
Ha ES et al. Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process. 2015 Drug Des Devel Ther pmid:26345723
Zaza KJ et al. Vulvar extrauterine endometrial stromal sarcoma: A case report and literature review. 2015 Hematol Oncol Stem Cell Ther pmid:25585306
Fan F et al. Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs. 2015 Toxicol. Sci. pmid:25752796
Kanat O Management of cancer cachexia (reply). 2014 Jan-Feb Tumori pmid:24675504