Norgestrel is a lipid of Sterol Lipids (ST) class. Norgestrel is associated with abnormalities such as Acne, Deep Vein Thrombosis, Thromboembolism, Activated Protein C Resistance and Hydrometra. The involved functions are known as Thrombosis, Aquatic environment, Venous Thrombosis, Thrombus and Inspiration function. Norgestrel often locates in Glial. The associated genes with Norgestrel are Genes, Reporter. The related lipids are Estranes.
To understand associated biological information of Norgestrel, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Norgestrel is suspected in Thromboembolism, Acne, Deep Vein Thrombosis, Activated Protein C Resistance, Hydrometra, Withdrawal bleeding and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Norgestrel
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Gynecomastia | D006177 | 6 associated lipids |
| Venous Thrombosis | D020246 | 11 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Hasegawa S et al. | Thromboembolic adverse event study of combined estrogen-progestin preparations using Japanese Adverse Drug Event Report database. | 2017 | PLoS ONE | pmid:28732067 |
| Kiechle M and Neuenfeldt M | Experience with oral emergency contraception since the OTC switch in Germany. | 2017 | Arch. Gynecol. Obstet. | pmid:27896473 |
| Kim DH et al. | Dilatation and curettage is more accurate than endometrial aspiration biopsy in early-stage endometrial cancer patients treated with high dose oral progestin and levonorgestrel intrauterine system. | 2017 | J Gynecol Oncol | pmid:27670255 |
| Festin MP et al. | Effect of BMI and body weight on pregnancy rates with LNG as emergency contraception: analysis of four WHO HRP studies. | 2017 | Contraception | pmid:27527670 |
| Chang T et al. | Patient or Clinician: Duration of Use of Intrauterine Devices Based on Who Initiated Discussion of Placement. | 2016 Jan-Feb | J Am Board Fam Med | pmid:26769874 |
| Gemzell-Danielsson K et al. | A Phase III, single-arm study of LNG-IUS 8, a low-dose levonorgestrel intrauterine contraceptive system (total content 13.5mg) in postmenarcheal adolescents. | 2016 | Contraception | pmid:26872720 |
| Festin MP et al. | A prospective, open-label, single arm, multicentre study to evaluate efficacy, safety and acceptability of pericoital oral contraception using levonorgestrel 1.5 mg. | 2016 | Hum. Reprod. | pmid:26830816 |
| Zhang D et al. | Association between knowledge about levonorgestrel emergency contraception and the risk of ectopic pregnancy following levonorgestrel emergency contraception failure: a comparative survey. | 2016 | Pharmacoepidemiol Drug Saf | pmid:26748685 |
| Samson M et al. | Progestin and breast cancer risk: a systematic review. | 2016 | Breast Cancer Res. Treat. | pmid:26700034 |
| Bullock H et al. | Pharmacy access to ulipristal acetate in Hawaii: is a prescription enough? | 2016 | Contraception | pmid:26689477 |
| Scarsi KK et al. | Unintended Pregnancies Observed With Combined Use of the Levonorgestrel Contraceptive Implant and Efavirenz-based Antiretroviral Therapy: A Three-Arm Pharmacokinetic Evaluation Over 48 Weeks. | 2016 | Clin. Infect. Dis. | pmid:26646680 |
| Phillips SJ et al. | Progestogen-only contraceptive use among breastfeeding women: a systematic review. | 2016 | Contraception | pmid:26410174 |
| Batur P et al. | Emergency contraception: A multispecialty survey of clinician knowledge and practices. | 2016 | Contraception | pmid:26363429 |
| Gungor T et al. | Clinicopathologic characteristics and treatment features of women with the incidental diagnosis of endometrial adenocarcinoma during infertility follow-up in Ankara, Turkey. | 2016 | Taiwan J Obstet Gynecol | pmid:27343306 |
| Hall AM and Kutler BA | Intrauterine contraception in nulliparous women: a prospective survey. | 2016 | J Fam Plann Reprod Health Care | pmid:25854550 |
| Leung VW et al. | Population-based evaluation of the effectiveness of two regimens for emergency contraception. | 2016 | Int J Gynaecol Obstet | pmid:26969148 |
| Westhoff CL et al. | Clotting factor changes during the first cycle of oral contraceptive use. | 2016 | Contraception | pmid:26452328 |
| Lobo Abascal P et al. | Differences in reporting Pearl Indices in the United States and Europe: Focus on a 91-day extended-regimen combined oral contraceptive with low-dose ethinyl estradiol supplementation. | 2016 | Eur J Contracept Reprod Health Care | pmid:26115381 |
| Apter D et al. | Bleeding pattern and cycle control with estetrol-containing combined oral contraceptives: results from a phase II, randomised, dose-finding study (FIESTA). | 2016 | Contraception | pmid:27153745 |
| Maybin JA and Critchley HO | Medical management of heavy menstrual bleeding. | 2016 | Womens Health (Lond) | pmid:26695687 |
| Cano-Nicolau J et al. | Several synthetic progestins disrupt the glial cell specific-brain aromatase expression in developing zebra fish. | 2016 | Toxicol. Appl. Pharmacol. | pmid:27245768 |
| Levonorgestrel-Releasing Intrauterine System (52 mg) for Idiopathic Heavy Menstrual Bleeding: A Health Technology Assessment. | 2016 | Ont Health Technol Assess Ser | pmid:27990196 | |
| Kai J et al. | Usual medical treatments or levonorgestrel-IUS for women with heavy menstrual bleeding: long-term randomised pragmatic trial in primary care. | 2016 | Br J Gen Pract | pmid:27884916 |
| Kim CR et al. | Immunologic evaluation of the endometrium with a levonorgestrel intrauterine device in solid organ transplant women and healthy controls. | 2016 | Contraception | pmid:27374735 |
| Mejia M et al. | Association of baseline bleeding pattern on amenorrhea with levonorgestrel intrauterine system use. | 2016 | Contraception | pmid:27364099 |
| Royer PA et al. | Choice of Emergency Contraceptive and Decision Making Regarding Subsequent Unintended Pregnancy. | 2016 | J Womens Health (Larchmt) | pmid:27032057 |
| Lopez LM et al. | Progestin-only contraceptives: effects on weight. | 2016 | Cochrane Database Syst Rev | pmid:27567593 |
| Csányi A et al. | The Effects of Female Sexual Hormones on the Expression of Aquaporin 5 in the Late-Pregnant Rat Uterus. | 2016 | Int J Mol Sci | pmid:27556454 |
| Ørbo A et al. | HE4 is a novel tissue marker for therapy response and progestin resistance in medium- and low-risk endometrial hyperplasia. | 2016 | Br. J. Cancer | pmid:27537387 |
| Villegas G et al. | A Novel Microbicide/Contraceptive Intravaginal Ring Protects Macaque Genital Mucosa against SHIV-RT Infection Ex Vivo. | 2016 | PLoS ONE | pmid:27428377 |
| Liegl S | Levonorgestrel-Releasing Intrauterine System vs. Oral Progestins for Treatment of Endometrial Hyperplasia. | 2016 | Am Fam Physician | pmid:27281840 |
| Phillips SJ et al. | The safety of Sino-implant (II) for women with medical conditions or other characteristics: a systematic review. | 2016 | Contraception | pmid:27217053 |
| Creinin MD et al. | Levonorgestrel release rates over 5 years with the Liletta® 52-mg intrauterine system. | 2016 | Contraception | pmid:27125892 |
| Sanghera S et al. | Pharmaceutical treatments to prevent recurrence of endometriosis following surgery: a model-based economic evaluation. | 2016 | BMJ Open | pmid:27084280 |
| Italia S and Brand H | Status of Emergency Contraceptives in Europe One Year after the European Medicines Agency's Recommendation to Switch Ulipristal Acetate to Non-Prescription Status. | 2016 | Public Health Genomics | pmid:27022731 |
| Quispe Calla NE et al. | Medroxyprogesterone acetate and levonorgestrel increase genital mucosal permeability and enhance susceptibility to genital herpes simplex virus type 2 infection. | 2016 | Mucosal Immunol | pmid:27007679 |
| Edelman AB et al. | Impact of obesity on the pharmacokinetics of levonorgestrel-based emergency contraception: single and double dosing. | 2016 | Contraception | pmid:27000996 |
| Motegi E et al. | Levonorgestrel-releasing intrauterine system placement for severe uterine cervical stenosis after conization: two case reports. | 2016 | J Med Case Rep | pmid:26960298 |
| Rowe P et al. | Safety and efficacy in parous women of a 52-mg levonorgestrel-medicated intrauterine device: a 7-year randomized comparative study with the TCu380A. | 2016 | Contraception | pmid:26916172 |
| Munro ML et al. | History, policy and nursing practice implications of the plan b(®) emergency contraceptive. | 2015 Apr-May | Nurs Womens Health | pmid:25900585 |
| Ruggeri JB et al. | Treatment and Follow-up of Human Papillomavirus Infected Women in a Municipality in Southern Brazil. | 2015 | Asian Pac. J. Cancer Prev. | pmid:26434868 |
| Schmid R | The Cost-Effectiveness of Emergency Hormonal Contraception with Ulipristal Acetate versus Levonorgestrel for Minors in France. | 2015 | PLoS ONE | pmid:26422259 |
| Diedrich JT et al. | Long-term utilization and continuation of intrauterine devices. | 2015 | Am. J. Obstet. Gynecol. | pmid:26409157 |
| Raine-Bennett T et al. | Reproductive health outcomes of insured adolescent and adult women who access oral levonorgestrel emergency contraception. | 2015 | Obstet Gynecol | pmid:25751211 |
| Ginstman C et al. | Contraceptive Use Before and After Gastric Bypass: a Questionnaire Study. | 2015 | Obes Surg | pmid:25744304 |
| Emergency contraception. Widely available and effective but disappointing as a public health intervention: a review. | 2015 | Hum. Reprod. | pmid:25678571 | |
| Baird AS et al. | Use of ulipristal acetate and levonorgestrel for emergency contraception: a follow-up study. | 2015 | J Fam Plann Reprod Health Care | pmid:24869461 |
| Duijkers IJ et al. | Inhibition of ovulation by administration of estetrol in combination with drospirenone or levonorgestrel: Results of a phase II dose-finding pilot study. | 2015 | Eur J Contracept Reprod Health Care | pmid:26394847 |
| McNicholas C et al. | Use of the etonogestrel implant and levonorgestrel intrauterine device beyond the U.S. Food and Drug Administration-approved duration. | 2015 | Obstet Gynecol | pmid:25730221 |