3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid is a lipid of Sterol Lipids (ST) class. 3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid is associated with abnormalities such as Cholestasis and Little's Disease. The involved functions are known as inhibitors, Signal Transduction, Phosphorylation, Cell Survival and Detergents. 3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid often locates in Protoplasm. The related lipids are Promega.
To understand associated biological information of 3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid is suspected in Cholestasis, Little's Disease and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Crohn Disease | D003424 | 12 associated lipids |
| Cholelithiasis | D002769 | 16 associated lipids |
| Blastomycosis | D001759 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Kushner DB and Ricciardi RP | Reduced phosphorylation of p50 is responsible for diminished NF-kappaB binding to the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells. | 1999 | Mol. Cell. Biol. | pmid:10022903 |
| Van Erpecum KJ and Van Berge-Henegouwen GP | Gallstones: an intestinal disease? | 1999 | Gut | pmid:10026334 |
| Morgan WA et al. | The role of ursodeoxycholic acid in bile acid-mediated kidney fragment toxicity. | 1999 | Exp. Toxicol. Pathol. | pmid:10048711 |
| Hayashi I and Majima M | Reduction of sodium deoxycholic acid-induced scratching behaviour by bradykinin B2 receptor antagonists. | 1999 | Br. J. Pharmacol. | pmid:10051136 |
| Barker DM and Corder R | Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. | 1999 | Br. J. Pharmacol. | pmid:10051151 |
| Tayeh MA et al. | Kinetic and mutagenic evidence for the role of histidine residues in the Lycopersicon esculentum 1-aminocyclopropane-1-carboxylic acid oxidase. | 1999 | J. Protein Chem. | pmid:10071929 |
| pmid:10075114 | ||||
| van Velkinburgh JC and Gunn JS | PhoP-PhoQ-regulated loci are required for enhanced bile resistance in Salmonella spp. | 1999 | Infect. Immun. | pmid:10084994 |
| pmid:10090844 |