Coprocholic acid

Coprocholic acid is a lipid of Sterol Lipids (ST) class. Coprocholic acid is associated with abnormalities such as Exanthema, Peroxisomal Disorders and Cholestatic liver disease. The involved functions are known as Protonation, Cytokinesis, Oxidation, Anabolism and Process. Coprocholic acid often locates in Blood, peroxisome, Membrane, Endoplasmic Reticulum and Mitochondria. The associated genes with Coprocholic acid are THEMIS gene. The related lipids are Fatty Acids, methyl cholate, pristanic acid and branched chain fatty acid.

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Introduction

To understand associated biological information of Coprocholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coprocholic acid?

Coprocholic acid is suspected in Exanthema, Cholestatic liver disease, Peroxisomal Disorders and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Coprocholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coprocholic acid?

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What functions are associated with Coprocholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coprocholic acid?

Related references are published most in these journals:

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What genes are associated with Coprocholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coprocholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Coprocholic acid

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Authors Title Published Journal PubMed Link
pmid:
ten Brink HJ et al. Heterogeneity in di/trihydroxycholestanoic acidaemia. 1994 Ann. Clin. Biochem. pmid:8060102
Dahlbäck H et al. Conversion of 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha, 26-tetrol into 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestanoic acid by rabbit liver mitochondria. 1988 Biochem. Biophys. Res. Commun. pmid:3288204
Dirkx R et al. Beta-oxidation in hepatocyte cultures from mice with peroxisomal gene knockouts. 2007 Biochem. Biophys. Res. Commun. pmid:17442273
Ostlund Farrants AK et al. Differential induction of peroxisomal oxidation of palmitic acid and 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid in rat liver. 1990 Biochim. Biophys. Acta pmid:2223856
Ostlund Farrants AK et al. Identification of 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholest-24-enoic acid as an intermediate in the peroxisomal conversion of 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid to cholic acid. 1989 Biochim. Biophys. Acta pmid:2930767
Croes K et al. Evidence for the importance of iron in the alpha-oxidation of 3-methyl-substituted fatty acids in the intact cell. 1995 Biochim. Biophys. Acta pmid:7893739
Wanders RJ et al. Accumulation and impaired in vivo metabolism of di- and trihydroxycholestanoic acid in two patients. 1991 Clin. Chim. Acta pmid:1839974
Setchell KD et al. Liver disease caused by failure to racemize trihydroxycholestanoic acid: gene mutation and effect of bile acid therapy. 2003 Gastroenterology pmid:12512044
Une M et al. Stereospecific formation of (24E)-3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholest-24-en-26-oic acid and (24R,25S)-3 alpha,7 alpha,12 alpha,24-tetrahydroxy-5 beta-cholestan-26-oic acid from either (25R)- or (25S)-3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestan-26-oic acid by rat liver homogenate. 1984 J. Biochem. pmid:6520115