Coprocholic acid

Coprocholic acid is a lipid of Sterol Lipids (ST) class. Coprocholic acid is associated with abnormalities such as Exanthema, Peroxisomal Disorders and Cholestatic liver disease. The involved functions are known as Protonation, Cytokinesis, Oxidation, Anabolism and Process. Coprocholic acid often locates in Blood, peroxisome, Membrane, Endoplasmic Reticulum and Mitochondria. The associated genes with Coprocholic acid are THEMIS gene. The related lipids are Fatty Acids, methyl cholate, pristanic acid and branched chain fatty acid.

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Introduction

To understand associated biological information of Coprocholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coprocholic acid?

Coprocholic acid is suspected in Exanthema, Cholestatic liver disease, Peroxisomal Disorders and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Coprocholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coprocholic acid?

Related references are published most in these journals:

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What functions are associated with Coprocholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coprocholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Coprocholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coprocholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Coprocholic acid

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Authors Title Published Journal PubMed Link
pmid:
Starchenkov I et al. A convenient synthesis of 5beta-cholestan-26-oic and 5beta-cholestan-26,27-dioic acids. 2000 Steroids pmid:10699593
Johnson DW et al. Rapid and quantitative analysis of unconjugated C(27) bile acids in plasma and blood samples by tandem mass spectrometry. 2001 J. Lipid Res. pmid:11160360
Ferdinandusse S et al. Plasma analysis of di- and trihydroxycholestanoic acid diastereoisomers in peroxisomal alpha-methylacyl-CoA racemase deficiency. 2001 J. Lipid Res. pmid:11160375
Setchell KD et al. Liver disease caused by failure to racemize trihydroxycholestanoic acid: gene mutation and effect of bile acid therapy. 2003 Gastroenterology pmid:12512044
Gootjes J et al. Reinvestigation of trihydroxycholestanoic acidemia reveals a peroxisome biogenesis disorder. 2004 Neurology pmid:15184617
Batta AK et al. Synthesis of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestan-26-oic acid from 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestan-26-oic acid: configuration in the bile of Alligator mississippiensis. 1992 Steroids pmid:1519259
Dirkx R et al. Beta-oxidation in hepatocyte cultures from mice with peroxisomal gene knockouts. 2007 Biochem. Biophys. Res. Commun. pmid:17442273
Wanders RJ et al. Accumulation and impaired in vivo metabolism of di- and trihydroxycholestanoic acid in two patients. 1991 Clin. Chim. Acta pmid:1839974
Batta AK et al. High-performance liquid chromatographic separation of bile acids and bile alcohols diastereoisomeric at C-25. 1991 J. Chromatogr. pmid:1874839