Trihydroxycoprostane

Trihydroxycoprostane is a lipid of Sterol Lipids (ST) class. The involved functions are known as Uptake, Enterohepatic Circulation, Metabolic Inhibition and Ionization. Trihydroxycoprostane often locates in Hepatic, Entire gastrointestinal tract and Abdominal Cavity. The related lipids are 3,7,12-trihydroxycoprostane, (3beta,5beta,7alpha,12alpha)-isomer, Cholestanes and scymnol.

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Introduction

To understand associated biological information of Trihydroxycoprostane, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Trihydroxycoprostane?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Trihydroxycoprostane

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Trihydroxycoprostane?

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What functions are associated with Trihydroxycoprostane?


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What lipids are associated with Trihydroxycoprostane?

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What genes are associated with Trihydroxycoprostane?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Trihydroxycoprostane?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Trihydroxycoprostane

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Authors Title Published Journal PubMed Link
pmid:24853400
pmid:
YASHIMA H Stero-bile acids and bile sterols. XLII. The synthesis of 3alpha,7alpha,12alpha-trihydroxycoprostane-[26,27-C14] and 3alpha,7alpha,12alpha,25-tetrahydroxycoprostane[26,27-C14]. 1962 J. Biochem. pmid:14040370
Gustafsson J Effect of biliary obstruction on 26-hydroxylation of C27-steroids in bile acid synthesis. 1978 J. Lipid Res. pmid:632686
Björkhem I et al. Assay of intermediates in bile acid biosynthesis using isotope dilution--mass spectrometry: hepatic levels in the normal state and in cerebrotendinous xanthomatosis. 1981 J. Lipid Res. pmid:7017048
Hansson R et al. 25-Hydroxylation vitamin D3 and side chain hydroxylations of 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol by purified rabbit and rat liver microsomal cytochromes P-450. 1981 J. Biol. Chem. pmid:6260795
Noshiro M et al. The involvement of cytochrome b5 in 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol 25-hydroxylation and taurodeoxycholate 7 alpha-hydroxylation of rat liver. 1982 Biochem. Biophys. Res. Commun. pmid:7115387
Dueland S et al. 26-hydroxylation of 5 beta-cholestane-3 alpha,7 alpha,12 alpha-triol by isolated nonparenchymal cells and hepatocytes from rat liver. 1982 J. Lipid Res. pmid:7161561
Freese DK and Hanson RF Neonatal cholestatic syndromes associated with alterations in bile acid synthesis. 1983 J. Pediatr. Gastroenterol. Nutr. pmid:6348235
Somanathan R and Krisans S Synthesis of C-22, C-23-3H-labeled 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestane. 1985 J. Lipid Res. pmid:4031656