Paricalcitol

Paricalcitol is a lipid of Sterol Lipids (ST) class. Paricalcitol is associated with abnormalities such as Vitamin D Deficiency. The involved functions are known as Hypertrophy, Left Ventricular. Paricalcitol often locates in Blood.

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Introduction

To understand associated biological information of Paricalcitol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Paricalcitol?

Paricalcitol is suspected in Vitamin D Deficiency and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Paricalcitol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Paricalcitol?

Related references are published most in these journals:

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What functions are associated with Paricalcitol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Paricalcitol?

There are no associated biomedical information in the current reference collection.

What genes are associated with Paricalcitol?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Paricalcitol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Paricalcitol

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Authors Title Published Journal PubMed Link
Torino C et al. Vitamin D and methylarginines in chronic kidney disease (CKD). 2017 PLoS ONE pmid:28976989
Chung S et al. Treatment combining aliskiren with paricalcitol is effective against progressive renal tubulointerstitial fibrosis via dual blockade of intrarenal renin. 2017 PLoS ONE pmid:28753620
Xun J et al. JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity. 2017 Oncotarget pmid:28423536
Poveda J et al. MXRA5 is a TGF-β1-regulated human protein with anti-inflammatory and anti-fibrotic properties. 2017 J. Cell. Mol. Med. pmid:27599751
Zheng JQ et al. Cholecalciferol Additively Reduces Serum Parathyroid Hormone and Increases Vitamin D and Cathelicidin Levels in Paricalcitol-Treated Secondary Hyperparathyroid Hemodialysis Patients. 2016 Nutrients pmid:27827962
Manjarres L et al. Budget impact of secondary hyperparathyroidism treatment in chronic kidney disease in an Ecuadorian social security hospital. 2016 BMC Health Serv Res pmid:27566059
Nieuwland AJ et al. Activation of the vitamin D receptor selectively interferes with calcineurin-mediated inflammation: a clinical evaluation in the abdominal aortic aneurysm. 2016 Lab. Invest. pmid:27239732
El-Shemi AG et al. Paricalcitol Enhances the Chemopreventive Efficacy of 5-Fluorouracil on an Intermediate-Term Model of Azoxymethane-Induced Colorectal Tumors in Rats. 2016 Cancer Prev Res (Phila) pmid:27020656
Lee AS et al. Paricalcitol attenuates lipopolysaccharide-induced myocardial inflammation by regulating the NF-κB signaling pathway. 2016 Int. J. Mol. Med. pmid:26954764
Egido J et al. The pleiotropic effects of paricalcitol: Beyond bone-mineral metabolism. 2016 Nefrologia pmid:26705959
Martinez-Moreno JM et al. Vitamin D modulates tissue factor and protease-activated receptor 2 expression in vascular smooth muscle cells. 2016 FASEB J. pmid:26700731
Riera M et al. Paricalcitol modulates ACE2 shedding and renal ADAM17 in NOD mice beyond proteinuria. 2016 Am. J. Physiol. Renal Physiol. pmid:26697977
Becs G et al. Pharmacological induction of ferritin prevents osteoblastic transformation of smooth muscle cells. 2016 J. Cell. Mol. Med. pmid:26499096
Stavenuiter AW et al. Protective Effects of Paricalcitol on Peritoneal Remodeling during Peritoneal Dialysis. 2015 Biomed Res Int pmid:26605330
Borrego Utiel FJ et al. Effect of paricalcitol on mineral bone metabolism in kidney transplant recipients with secondary hyperparathyroidism. 2015 Nefrologia pmid:26306956
Dauletbaev N et al. Down-regulation of IL-8 by high-dose vitamin D is specific to hyperinflammatory macrophages and involves mechanisms beyond up-regulation of DUSP1. 2015 Br. J. Pharmacol. pmid:26178144
Zerr P et al. Vitamin D receptor regulates TGF-β signalling in systemic sclerosis. 2015 Ann. Rheum. Dis. pmid:24448349
Brakta S et al. Role of vitamin D in uterine fibroid biology. 2015 Fertil. Steril. pmid:26079694
Morgado-Pascual JL et al. Paricalcitol Inhibits Aldosterone-Induced Proinflammatory Factors by Modulating Epidermal Growth Factor Receptor Pathway in Cultured Tubular Epithelial Cells. 2015 Biomed Res Int pmid:26064952
Dáňová K et al. NF-κB, p38 MAPK, ERK1/2, mTOR, STAT3 and increased glycolysis regulate stability of paricalcitol/dexamethasone-generated tolerogenic dendritic cells in the inflammatory environment. 2015 Oncotarget pmid:26053099
Stavenuiter AW et al. A novel rat model of vitamin D deficiency: safe and rapid induction of vitamin D and calcitriol deficiency without hyperparathyroidism. 2015 Biomed Res Int pmid:25815325
Riccio E et al. Effect of paricalcitol vs calcitriol on hemoglobin levels in chronic kidney disease patients: a randomized trial. 2015 PLoS ONE pmid:25781618
Ritter CS et al. Differential expression and regulation of Klotho by paricalcitol in the kidney, parathyroid, and aorta of uremic rats. 2015 Kidney Int. pmid:25692955
Thethi TK et al. Effect of paricalcitol on endothelial function and inflammation in type 2 diabetes and chronic kidney disease. 2015 J. Diabetes Complicat. pmid:25633573
Bover J et al. Vitamin D, vitamin D receptor and the importance of its activation in patients with chronic kidney disease. 2015 Nefrologia pmid:25611831
Kröpelin TF et al. Number and frequency of albuminuria measurements in clinical trials in diabetic nephropathy. 2015 Clin J Am Soc Nephrol pmid:25568217
Trillini M et al. Paricalcitol for secondary hyperparathyroidism in renal transplantation. 2015 J. Am. Soc. Nephrol. pmid:25194004
Cozzolino M et al. Paricalcitol- or cinacalcet-centred therapy affects markers of bone mineral disease in patients with secondary hyperparathyroidism receiving haemodialysis: results of the IMPACT-SHPT study. 2014 Nephrol. Dial. Transplant. pmid:24500308
Donate-Correa J et al. Selective vitamin D receptor activation as anti-inflammatory target in chronic kidney disease. 2014 Mediators Inflamm. pmid:24511210
Eren Z et al. Effects of paricalcitol and aliskiren combination therapy on experimental diabetic nephropathy model in rats. 2014 Kidney Blood Press. Res. pmid:25532067
Duffy MM et al. Mesenchymal stem cells and a vitamin D receptor agonist additively suppress T helper 17 cells and the related inflammatory response in the kidney. 2014 Am. J. Physiol. Renal Physiol. pmid:25339699
Sahin I et al. Paricalcitol counteracts the increased contrast induced nephropathy caused by renin-angiotensin-aldosterone system blockade therapy in a rat model. 2014 Eur Rev Med Pharmacol Sci pmid:25339484
Ritter C et al. Cardiac and renal effects of atrasentan in combination with enalapril and paricalcitol in uremic rats. 2014 Kidney Blood Press. Res. pmid:25300759
González-Mateo GT et al. Paricalcitol reduces peritoneal fibrosis in mice through the activation of regulatory T cells and reduction in IL-17 production. 2014 PLoS ONE pmid:25279459
Choudhury S et al. Abnormal calcium handling and exaggerated cardiac dysfunction in mice with defective vitamin d signaling. 2014 PLoS ONE pmid:25268137
Zoccali C et al. Paricalcitol and endothelial function in chronic kidney disease trial. 2014 Hypertension pmid:25259743
Hansen D et al. The influence of vitamin D analogs on calcification modulators, N-terminal pro-B-type natriuretic peptide and inflammatory markers in hemodialysis patients: a randomized crossover study. 2014 BMC Nephrol pmid:25112372
Suarez-Martinez E et al. Adiponectin expression and the cardioprotective role of the vitamin D receptor activator paricalcitol and the angiotensin converting enzyme inhibitor enalapril in ApoE-deficient mice. 2014 Ther Adv Cardiovasc Dis pmid:25037058
Carpenter TO et al. Effect of paricalcitol on circulating parathyroid hormone in X-linked hypophosphatemia: a randomized, double-blind, placebo-controlled study. 2014 J. Clin. Endocrinol. Metab. pmid:25029424
Coyne DW et al. A randomized multicenter trial of paricalcitol versus calcitriol for secondary hyperparathyroidism in stages 3-4 CKD. 2014 Clin J Am Soc Nephrol pmid:24970869
Halder SK et al. Paricalcitol, a vitamin d receptor activator, inhibits tumor formation in a murine model of uterine fibroids. 2014 Reprod Sci pmid:24925855
Manucha W [Mitochondria and oxidative stress participation in renal inflammatory process]. 2014 Medicina (B Aires) pmid:24918679
Lee JW et al. Renoprotective effect of paricalcitol via a modulation of the TLR4-NF-κB pathway in ischemia/reperfusion-induced acute kidney injury. 2014 Biochem. Biophys. Res. Commun. pmid:24434153
Sezer S et al. Differential influence of vitamin D analogs on left ventricular mass index in maintenance hemodialysis patients. 2014 Int J Artif Organs pmid:24619898
Ellam T et al. Vitamin D deficiency and exogenous vitamin D excess similarly increase diffuse atherosclerotic calcification in apolipoprotein E knockout mice. 2014 PLoS ONE pmid:24586387
Gueutin V et al. [Diabetic nephropathy: emerging treatments]. 2014 Nephrol. Ther. pmid:24938412
Rubel D et al. Antifibrotic, nephroprotective effects of paricalcitol versus calcitriol on top of ACE-inhibitor therapy in the COL4A3 knockout mouse model for progressive renal fibrosis. 2014 Nephrol. Dial. Transplant. pmid:24198271
Pauwels S et al. Minimal interference from paricalcitol (Zemplar®) in underivatized 1,25-dihydroxyvitamin D LC-MS/MS assays. 2014 Clin. Chim. Acta pmid:24326126
Guo C et al. Synergistic induction of human cathelicidin antimicrobial peptide gene expression by vitamin D and stilbenoids. 2014 Mol Nutr Food Res pmid:24039193
Yan Y et al. Efficacy and initial dose determination of paricalcitol for treatment of secondary hyperparathyroidism in Chinese subjects. 2014 Clin. Nephrol. pmid:24131674