MeSH term | MeSH ID | Detail |
---|---|---|
Sex Chromosome Aberrations | D012729 | 2 associated lipids |
Ichthyosis | D007057 | 3 associated lipids |
Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
Cholesterol sulfate is a lipid of Sterol Lipids (ST) class. Cholesterol sulfate is associated with abnormalities such as Dental caries, Liver Cirrhosis, Ichthyosis, X-Linked, Retention hyperkeratosis and Dermatologic disorders. The involved functions are known as arachidonic acid metabolic process, Induced platelet aggregation, release of sequestered calcium ion into cytoplasm, Regulation and Platelet adhesion, function. Cholesterol sulfate often locates in Skin, Membrane, Body tissue, Human tissue and Tissue membrane. The associated genes with cholesterol sulfate are FAM3A gene, MMP gene, TSKU gene, FATE1 gene and TGM3 gene. The related lipids are Sterols, Steroids, Hydroxycholesterols, 7-dehydrocholesterol and Dehydrocholesterols.
To understand associated biological information of cholesterol sulfate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
cholesterol sulfate is suspected in Ichthyosis, X-Linked, Steroid Sulfatase Deficiency Disease, Ichthyoses, Liver Cirrhosis, Retention hyperkeratosis, Dermatologic disorders and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with cholesterol sulfate
MeSH term | MeSH ID | Detail |
---|---|---|
Sex Chromosome Aberrations | D012729 | 2 associated lipids |
Ichthyosis | D007057 | 3 associated lipids |
Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Wang Z et al. | Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury. | 2017 | Arch. Toxicol. | pmid:27052460 |
Pullmannová P et al. | Permeability and microstructure of model stratum corneum lipid membranes containing ceramides with long (C16) and very long (C24) acyl chains. | 2017 | Biophys. Chem. | pmid:28363088 |
Kumar Gaur P et al. | Nanovesicles of nitrendipine with lipid complex for transdermal delivery: pharmacokinetic and pharmacodynamic studies. | 2016 | Artif Cells Nanomed Biotechnol | pmid:26375758 |
Vickman RE et al. | Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer. | 2016 | Mol. Cancer Res. | pmid:27341831 |
Wang F et al. | Inhibition of T cell receptor signaling by cholesterol sulfate, a naturally occurring derivative of membrane cholesterol. | 2016 | Nat. Immunol. | pmid:27213689 |
Benesch MG et al. | A calorimetric and spectroscopic comparison of the effects of cholesterol and its sulfur-containing analogs thiocholesterol and cholesterol sulfate on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine bilayer membranes. | 2016 | Biochim. Biophys. Acta | pmid:26585353 |
Sánchez-Guijo A et al. | Simultaneous quantification of cholesterol sulfate, androgen sulfates, and progestagen sulfates in human serum by LC-MS/MS. | 2015 | J. Lipid Res. | pmid:26239050 |
Seneff S et al. | A novel hypothesis for atherosclerosis as a cholesterol sulfate deficiency syndrome. | 2015 | Theor Biol Med Model | pmid:26014131 |
Mi-ichi F et al. | Entamoeba mitosomes play an important role in encystation by association with cholesteryl sulfate synthesis. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25986376 |
Sánchez-Guijo A et al. | High levels of oxysterol sulfates in serum of patients with steroid sulfatase deficiency. | 2015 | J. Lipid Res. | pmid:25502769 |