Glycocholic Acid

Glycocholic acid is a lipid of Sterol Lipids (ST) class. Glycocholic acid is associated with abnormalities such as Gastric ulcer, Kissing ulcers, Liver Cirrhosis, Hepatitis and Wiskott-Aldrich Syndrome. The involved functions are known as Stimulus, Ulcer, Pressure- physical agent, Regulation and Uptake. Glycocholic acid often locates in Mucous Membrane, Gastric mucosa, Hepatic and Blood. The associated genes with Glycocholic Acid are AGXT gene, FABP6 gene and glycine methyl ester hydrochloride. The related lipids are Sterols.

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Introduction

To understand associated biological information of Glycocholic Acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glycocholic Acid?

Glycocholic Acid is suspected in Liver Cirrhosis, Hepatitis, Gastric ulcer, Kissing ulcers, Cholestasis and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Glycocholic Acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glycocholic Acid?

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What functions are associated with Glycocholic Acid?


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What lipids are associated with Glycocholic Acid?

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What genes are associated with Glycocholic Acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glycocholic Acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Glycocholic Acid

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Authors Title Published Journal PubMed Link
Yu XH et al. Biomarkers of unstable angina pectoris and yangxin decoction intervention: An exploratory metabonomics study of blood plasma. 2017 Medicine (Baltimore) pmid:28538412
Xu H et al. Serum Metabonomics of Mild Acute Pancreatitis. 2016 J. Clin. Lab. Anal. pmid:27169745
Ling G et al. Synergistic and complete reversal of the multidrug resistance of mitoxantrone hydrochloride by three-in-one multifunctional lipid-sodium glycocholate nanocarriers based on simultaneous BCRP and Bcl-2 inhibition. 2016 Int J Nanomedicine pmid:27601896
Maroni A et al. In vitro and in vivo evaluation of an oral multiple-unit formulation for colonic delivery of insulin. 2016 Eur J Pharm Biopharm pmid:27519826
Horváth G et al. Structural determinants of ligand binding in the ternary complex of human ileal bile acid binding protein with glycocholate and glycochenodeoxycholate obtained from solution NMR. 2016 FEBS J. pmid:26613247
Heubi JE et al. Treatment of bile acid amidation defects with glycocholic acid. 2015 Hepatology pmid:25163551
Luo L et al. Evaluation of serum bile acid profiles as biomarkers of liver injury in rodents. 2014 Toxicol. Sci. pmid:24085190
Kobayashi T et al. Exploration of novel predictive markers in rat plasma of the early stages of chronic renal failure. 2014 Anal Bioanal Chem pmid:24232639
Herfindal L et al. Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3. 2014 PLoS ONE pmid:24740327
Cheng X et al. Decreased bile-acid synthesis in livers of hepatocyte-conditional NADPH-cytochrome P450 reductase-null mice results in increased bile acids in serum. 2014 J. Pharmacol. Exp. Ther. pmid:25034404
Zhang A et al. Urinary metabolic profiling identifies a key role for glycocholic acid in human liver cancer by ultra-performance liquid-chromatography coupled with high-definition mass spectrometry. 2013 Clin. Chim. Acta pmid:23313056
Favretto F et al. Ligand binding promiscuity of human liver fatty acid binding protein: structural and dynamic insights from an interaction study with glycocholate and oleate. 2013 Chembiochem pmid:23757005
Mitome H et al. An efficient laboratory-scale preparative method for [1-(13)C]glycocholic acid. 2013 J Labelled Comp Radiopharm pmid:24285191
Hu S et al. Integrity and stability of oral liposomes containing bile salts studied in simulated and ex vivo gastrointestinal media. 2013 Int J Pharm pmid:23089580
Matyja A et al. Telocytes: new insight into the pathogenesis of gallstone disease. 2013 J. Cell. Mol. Med. pmid:23551596
Das N et al. Statistical optimization of insulin-loaded Pluronic F-127 gels for buccal delivery of basal insulin. 2012 May-Jun Pharm Dev Technol pmid:21214425
Horváth G et al. Internal motions and exchange processes in human ileal bile acid binding protein as studied by backbone (15)N nuclear magnetic resonance spectroscopy. 2012 Biochemistry pmid:22329738
Cai W et al. A propofol microemulsion with low free propofol in the aqueous phase: formulation, physicochemical characterization, stability and pharmacokinetics. 2012 Int J Pharm pmid:22814221
Niu M et al. Hypoglycemic activity and oral bioavailability of insulin-loaded liposomes containing bile salts in rats: the effect of cholate type, particle size and administered dose. 2012 Eur J Pharm Biopharm pmid:22369880
Song X et al. Nimodipine-loaded mixed micelles: formulation, compatibility, pharmacokinetics, and vascular irritability study. 2012 Int J Nanomedicine pmid:22888228
Lim SM and Ahn DH Factors affecting adhesion of lactic acid bacteria to Caco-2 cells and inhibitory effect on infection of Salmonella typhimurium. 2012 J. Microbiol. Biotechnol. pmid:23221537
Najafzadeh H et al. Evaluation of an oral insulin formulation in normal and diabetic rats. 2012 Indian J Pharmacol pmid:22345880
Ressom HW et al. Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis. 2012 Anal. Chim. Acta pmid:22882828
Marion TL et al. Endogenous bile acid disposition in rat and human sandwich-cultured hepatocytes. 2012 Toxicol. Appl. Pharmacol. pmid:22342602
Studer E et al. Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes. 2012 Hepatology pmid:21932398
Mengersen F and Bunjes H Chemical stability of phospholipid-stabilized supercooled smectic cholesteryl myristate nanoparticles. 2012 Eur J Pharm Biopharm pmid:22750438
Devkota S et al. Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice. 2012 Nature pmid:22722865
Zhang Y et al. Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism in mice. 2012 PLoS ONE pmid:22496825
Mohn WW et al. Gene cluster encoding cholate catabolism in Rhodococcus spp. 2012 J. Bacteriol. pmid:23024343
Okoli AS et al. Effects of human and porcine bile on the proteome of Helicobacter hepaticus. 2012 Proteome Sci pmid:22533459
Chen X et al. Bile salts disrupt human esophageal squamous epithelial barrier function by modulating tight junction proteins. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:22575221
Schönbeck C et al. Higher order inclusion complexes and secondary interactions studied by global analysis of calorimetric titrations. 2012 Anal. Chem. pmid:22292412
Jiang H et al. Application of ultra-performance liquid chromatography coupled with mass spectrometry to metabonomic study on spontaneously hypertensive rats and intervention effects of Ping Gan prescription. 2012 J Sep Sci pmid:22282408
Nicklasson M et al. Expression of colonization factor CS5 of enterotoxigenic Escherichia coli (ETEC) is enhanced in vivo and by the bile component Na glycocholate hydrate. 2012 PLoS ONE pmid:22563407
Frisch K et al. [N-methyl-11C]cholylsarcosine, a novel bile acid tracer for PET/CT of hepatic excretory function: radiosynthesis and proof-of-concept studies in pigs. 2012 J. Nucl. Med. pmid:22454486
Tiengo A et al. Chemical composition and bile acid binding activity of products obtained from amaranth (Amaranthus cruentus) seeds. 2011 Plant Foods Hum Nutr pmid:21901402
Marchesini MI et al. Brucella abortus choloylglycine hydrolase affects cell envelope composition and host cell internalization. 2011 PLoS ONE pmid:22174816
Qiao X et al. Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry. 2011 J Chromatogr A pmid:21111425
Petersen S et al. The physical state of lipid nanoparticles influences their effect on in vitro cell viability. 2011 Eur J Pharm Biopharm pmid:21458564
Li X et al. Novel mucus-penetrating liposomes as a potential oral drug delivery system: preparation, in vitro characterization, and enhanced cellular uptake. 2011 Int J Nanomedicine pmid:22163166
Li JY et al. Effect of tween series on growth and Cis-9, trans-11 conjugated linoleic acid production of Lactobacillus acidophilus F0221 in the presence of bile salts. 2011 Int J Mol Sci pmid:22272124
de la Guardia RD et al. Purification and characterization of a protein capable of binding to fatty acids and bile salts in Giardia lamblia. 2011 J. Parasitol. pmid:21506852
Kong W et al. Antifungal evaluation of cholic acid and its derivatives on Candida albicans by microcalorimetry and chemometrics. 2011 Anal. Chim. Acta pmid:21397081
Xiang X et al. No significant effect of the SLCO1B1 polymorphism on the pharmacokinetics of ursodeoxycholic acid. 2011 Eur. J. Clin. Pharmacol. pmid:21655991
Oh DH et al. Enhanced transbuccal salmon calcitonin (sCT) delivery: effect of chemical enhancers and electrical assistance on in vitro sCT buccal permeation. 2011 Eur J Pharm Biopharm pmid:21683790
Bortolini O et al. Relative acidity scale of glycine- and taurine-conjugated bile acids through ESI-MS measurements. 2011 Steroids pmid:21371488
Del Curto MD et al. Oral delivery system for two-pulse colonic release of protein drugs and protease inhibitor/absorption enhancer compounds. 2011 J Pharm Sci pmid:21465487
Chen X et al. Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins. 2011 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:21617116
Matsumoto K et al. Bile acid-binding ability of kaki-tannin from young fruits of persimmon (Diospyros kaki) in vitro and in vivo. 2011 Phytother Res pmid:20922818
Chen J et al. Serum 27-nor-5β-cholestane-3,7,12,24,25 pentol glucuronide discovered by metabolomics as potential diagnostic biomarker for epithelium ovarian cancer. 2011 J. Proteome Res. pmid:21456628