Glycochenodeoxycholic acid

Glycochenodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Glycochenodeoxycholic acid is associated with abnormalities such as Cholestasis. The involved functions are known as Apoptosis, Process, Cytokinesis and Necrosis. Glycochenodeoxycholic acid often locates in Cell surface. The associated genes with Glycochenodeoxycholic acid are SLC10A1 gene, TNFSF10 gene, AKR1C2 gene and HSPA5 gene. The related lipids are glycoursodeoxycholic acid.

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Introduction

To understand associated biological information of Glycochenodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glycochenodeoxycholic acid?

Glycochenodeoxycholic acid is suspected in Cholestasis and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Glycochenodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glycochenodeoxycholic acid?

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What functions are associated with Glycochenodeoxycholic acid?


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What lipids are associated with Glycochenodeoxycholic acid?

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What genes are associated with Glycochenodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glycochenodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Glycochenodeoxycholic acid

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Authors Title Published Journal PubMed Link
pmid:
Fadden K et al. Steroid metabolism along the gastrointestinal tract of the cannulated pig. 1999 Eur. J. Cancer Prev. pmid:10091041
Gumpricht E et al. Glutathione status of isolated rat hepatocytes affects bile acid-induced cellular necrosis but not apoptosis. 2000 Toxicol. Appl. Pharmacol. pmid:10739750
Rust C et al. The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade. 2000 J. Biol. Chem. pmid:10770953
Sodeman T et al. Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas. 2000 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:10859230
Gonzalez B et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. 2000 Mol. Cell. Biochem. pmid:10888222
Webster CR and Anwer MS Phosphoinositide 3-kinase, but not mitogen-activated protein kinase, pathway is involved in hepatocyte growth factor-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes. 2001 Hepatology pmid:11230741
Yerushalmi B et al. Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition. 2001 Hepatology pmid:11230742
Takikawa Y et al. The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits Fas apoptosis upstream of bid in rodent hepatocytes. 2001 Gastroenterology pmid:11375961
Danchenko E et al. Effect of bile acids on the proliferative activity and apoptosis of rat hepatocytes. 2001 Exp. Toxicol. Pathol. pmid:11484843