Glycochenodeoxycholic acid

Glycochenodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Glycochenodeoxycholic acid is associated with abnormalities such as Cholestasis. The involved functions are known as Apoptosis, Process, Cytokinesis and Necrosis. Glycochenodeoxycholic acid often locates in Cell surface. The associated genes with Glycochenodeoxycholic acid are SLC10A1 gene, TNFSF10 gene, AKR1C2 gene and HSPA5 gene. The related lipids are glycoursodeoxycholic acid.

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Introduction

To understand associated biological information of Glycochenodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glycochenodeoxycholic acid?

Glycochenodeoxycholic acid is suspected in Cholestasis and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Glycochenodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glycochenodeoxycholic acid?

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What functions are associated with Glycochenodeoxycholic acid?


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What lipids are associated with Glycochenodeoxycholic acid?

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What genes are associated with Glycochenodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glycochenodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Glycochenodeoxycholic acid

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Authors Title Published Journal PubMed Link
Higuchi H et al. The bile acid glycochenodeoxycholate induces trail-receptor 2/DR5 expression and apoptosis. 2001 J. Biol. Chem. pmid:11507096
Dilworth C et al. Spontaneous nitric oxide in hepatocyte monolayers and inhibition of compound-induced apoptosis. 2001 Toxicol In Vitro pmid:11698161
Higuchi H et al. Bid antisense attenuates bile acid-induced apoptosis and cholestatic liver injury. 2001 J. Pharmacol. Exp. Ther. pmid:11714870
Zhang F et al. Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids. 2001 Gastroenterology pmid:11729118
Li D et al. [Bile salt induces apoptosis of hepatocytes: the mechanism of hepatic function injury during obstructive jaundice]. 1998 Zhonghua Wai Ke Za Zhi pmid:11825482
Gumpricht E et al. Nitric oxide ameliorates hydrophobic bile acid-induced apoptosis in isolated rat hepatocytes by non-mitochondrial pathways. 2002 J. Biol. Chem. pmid:12006578
Yamashita Y et al. High metabolic function of primary human and porcine hepatocytes in a polyurethane foam/spheroid culture system in plasma from patients with fulminant hepatic failure. 2002 Cell Transplant pmid:12162378
pmid:12240947
Graf D et al. Prevention of bile acid-induced apoptosis by betaine in rat liver. 2002 Hepatology pmid:12297830
pmid:12401120