Glycochenodeoxycholic acid

Glycochenodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Glycochenodeoxycholic acid is associated with abnormalities such as Cholestasis. The involved functions are known as Apoptosis, Process, Cytokinesis and Necrosis. Glycochenodeoxycholic acid often locates in Cell surface. The associated genes with Glycochenodeoxycholic acid are SLC10A1 gene, TNFSF10 gene, AKR1C2 gene and HSPA5 gene. The related lipids are glycoursodeoxycholic acid.

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Introduction

To understand associated biological information of Glycochenodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glycochenodeoxycholic acid?

Glycochenodeoxycholic acid is suspected in Cholestasis and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Glycochenodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glycochenodeoxycholic acid?

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What functions are associated with Glycochenodeoxycholic acid?


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What lipids are associated with Glycochenodeoxycholic acid?

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What genes are associated with Glycochenodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glycochenodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Glycochenodeoxycholic acid

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Authors Title Published Journal PubMed Link
Jones BA et al. Bile salt-induced apoptosis of hepatocytes involves activation of protein kinase C. 1997 Am. J. Physiol. pmid:9176220
Coffin B et al. Local regulation of ileal tone in healthy humans. 1997 Am. J. Physiol. pmid:9038888
Jones B et al. Cystatin A expression reduces bile salt-induced apoptosis in a rat hepatoma cell line. 1998 Am. J. Physiol. pmid:9756503
Craddock AL et al. Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter. 1998 Am. J. Physiol. pmid:9458785
Pandak WM et al. Hep G2 cells: a model for studies on regulation of human cholesterol 7alpha-hydroxylase at the molecular level. 1996 Am. J. Physiol. pmid:8638705
Johnston A et al. cAMP-guanine exchange factor protection from bile acid-induced hepatocyte apoptosis involves glycogen synthase kinase regulation of c-Jun NH2-terminal kinase. 2011 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:21546580
Gates A et al. cAMP-GEF cytoprotection by Src tyrosine kinase activation of phosphoinositide-3-kinase p110 beta/alpha in rat hepatocytes. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:19196950
Webster CR et al. Protein kinase Cδ protects against bile acid apoptosis by suppressing proapoptotic JNK and BIM pathways in human and rat hepatocytes. 2014 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:25359536
Rust C et al. Phosphatidylinositol 3-kinase-dependent signaling modulates taurochenodeoxycholic acid-induced liver injury and cholestasis in perfused rat livers. 2005 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15746212
Zhang JH et al. Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids. 2013 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:23518683