Tetrahydrodeoxycorticosterone

Tetrahydrodeoxycorticosterone is a lipid of Sterol Lipids (ST) class. Tetrahydrodeoxycorticosterone is associated with abnormalities such as Cerebrovascular accident, Epilepsy, Status Epilepticus, Still and Liver diseases. The involved functions are known as Chromosome Pairing, Adjudication, inhibitors, Neuronal Transmission and Synthesis. Tetrahydrodeoxycorticosterone often locates in Entire oral cavity, Body tissue, Pole, Brain region and Cell surface. The associated genes with Tetrahydrodeoxycorticosterone are ADRBK1 gene. The related lipids are pregnane-20-one, allotetrahydrodeoxycorticosterone, Steroids, 17-phenylandrost-16-en-3-ol and pregnenolone sulfate. The related experimental models are Transgenic Model.

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Introduction

To understand associated biological information of Tetrahydrodeoxycorticosterone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tetrahydrodeoxycorticosterone?

Tetrahydrodeoxycorticosterone is suspected in Cerebrovascular accident, Epilepsy, Hepatic Encephalopathy, Status Epilepticus, Liver diseases, Convulsions and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tetrahydrodeoxycorticosterone

MeSH term MeSH ID Detail
Epilepsy, Absence D004832 5 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Tetrahydrodeoxycorticosterone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tetrahydrodeoxycorticosterone?

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What functions are associated with Tetrahydrodeoxycorticosterone?


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What lipids are associated with Tetrahydrodeoxycorticosterone?

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What genes are associated with Tetrahydrodeoxycorticosterone?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tetrahydrodeoxycorticosterone?

Transgenic Model

Transgenic Model are used in the study 'GABAA receptor modulating steroid antagonists (GAMSA) are functional in vivo.' (Johansson M et al., 2016).

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NCBI Entrez Crosslinks

All references with Tetrahydrodeoxycorticosterone

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Authors Title Published Journal PubMed Link
EADE NR The distribution of the catechol amines in homogenates of the bovine adrenal medulla. 1958 J. Physiol. (Lond.) pmid:13539831
Winkel CA et al. Production rate of deoxycorticosterone in women during the follicular and luteal phases of the ovarian cycle: the role of extraadrenal 21-hydroxylation of circulating progesterone in deoxycorticosterone production. 1980 J. Clin. Endocrinol. Metab. pmid:7440700
Casey ML and MacDonald PC Origin and production rates of deoxycorticosterone and deoxycorticosterone sulfate in men and nonpregnant women. 1983 J. Clin. Endocrinol. Metab. pmid:6822643
Crawley JN et al. Anxiolytic activity of an endogenous adrenal steroid. 1986 Brain Res. pmid:2879610
Majewska MD et al. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. 1986 Science pmid:2422758
Ehlers ME et al. Elevated urinary 19-Nor-deoxycorticosterone glucuronide in Cushing's syndrome. 1987 J. Clin. Endocrinol. Metab. pmid:3558730
Im WB et al. Studies on the mechanism of interactions between anesthetic steroids and gamma-aminobutyric acidA receptors. 1990 Mol. Pharmacol. pmid:2156155
Puia G et al. Neurosteroids act on recombinant human GABAA receptors. 1990 Neuron pmid:2160838
Morrow AL et al. Characterization of steroid interactions with gamma-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites. 1990 Mol. Pharmacol. pmid:1689453
Purdy RH et al. Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain. 1991 Proc. Natl. Acad. Sci. U.S.A. pmid:1852011