MeSH term | MeSH ID | Detail |
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Epilepsy, Absence | D004832 | 5 associated lipids |
Tetrahydrodeoxycorticosterone is a lipid of Sterol Lipids (ST) class. Tetrahydrodeoxycorticosterone is associated with abnormalities such as Cerebrovascular accident, Epilepsy, Status Epilepticus, Still and Liver diseases. The involved functions are known as Chromosome Pairing, Adjudication, inhibitors, Neuronal Transmission and Synthesis. Tetrahydrodeoxycorticosterone often locates in Entire oral cavity, Body tissue, Pole, Brain region and Cell surface. The associated genes with Tetrahydrodeoxycorticosterone are ADRBK1 gene. The related lipids are pregnane-20-one, allotetrahydrodeoxycorticosterone, Steroids, 17-phenylandrost-16-en-3-ol and pregnenolone sulfate. The related experimental models are Transgenic Model.
To understand associated biological information of Tetrahydrodeoxycorticosterone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tetrahydrodeoxycorticosterone is suspected in Cerebrovascular accident, Epilepsy, Hepatic Encephalopathy, Status Epilepticus, Liver diseases, Convulsions and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tetrahydrodeoxycorticosterone
MeSH term | MeSH ID | Detail |
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Epilepsy, Absence | D004832 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Transgenic Model are used in the study 'GABAA receptor modulating steroid antagonists (GAMSA) are functional in vivo.' (Johansson M et al., 2016).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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EADE NR | The distribution of the catechol amines in homogenates of the bovine adrenal medulla. | 1958 | J. Physiol. (Lond.) | pmid:13539831 |
Winkel CA et al. | Production rate of deoxycorticosterone in women during the follicular and luteal phases of the ovarian cycle: the role of extraadrenal 21-hydroxylation of circulating progesterone in deoxycorticosterone production. | 1980 | J. Clin. Endocrinol. Metab. | pmid:7440700 |
Casey ML and MacDonald PC | Origin and production rates of deoxycorticosterone and deoxycorticosterone sulfate in men and nonpregnant women. | 1983 | J. Clin. Endocrinol. Metab. | pmid:6822643 |
Crawley JN et al. | Anxiolytic activity of an endogenous adrenal steroid. | 1986 | Brain Res. | pmid:2879610 |
Majewska MD et al. | Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. | 1986 | Science | pmid:2422758 |
Ehlers ME et al. | Elevated urinary 19-Nor-deoxycorticosterone glucuronide in Cushing's syndrome. | 1987 | J. Clin. Endocrinol. Metab. | pmid:3558730 |
Im WB et al. | Studies on the mechanism of interactions between anesthetic steroids and gamma-aminobutyric acidA receptors. | 1990 | Mol. Pharmacol. | pmid:2156155 |
Puia G et al. | Neurosteroids act on recombinant human GABAA receptors. | 1990 | Neuron | pmid:2160838 |
Morrow AL et al. | Characterization of steroid interactions with gamma-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites. | 1990 | Mol. Pharmacol. | pmid:1689453 |
Purdy RH et al. | Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1852011 |