Tetradecanoic acid

Tetradecanoic acid is a lipid of Fatty Acyls (FA) class. Tetradecanoic acid is associated with abnormalities such as Chronic lung disease, Infection, Spastic syndrome, Diabetes and Cardiovascular Diseases. The involved functions are known as Fatty acid biosynthetic process, Anabolism, lung alveolus development, 5-(carboxyamino)imidazole ribonucleotide mutase activity and Homeostasis. Tetradecanoic acid often locates in Structure of parenchyma of lung, Blood, Head, Membrane and Cytoplasmic matrix. The associated genes with Tetradecanoic acid are SLC33A1 gene, SFTPA1 gene, P4HTM gene, Polypeptides and GPR132 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, palmitoleic acid, Phosphatidylglycerols and Butanols.

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Introduction

To understand associated biological information of Tetradecanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tetradecanoic acid?

Tetradecanoic acid is suspected in Infection, Cardiovascular Diseases, Obesity, Chronic lung disease, Diabetes, Diabetes Mellitus, Non-Insulin-Dependent and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tetradecanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Breast Neoplasms D001943 24 associated lipids
Lung Neoplasms D008175 171 associated lipids
Insulinoma D007340 28 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Body Weight D001835 333 associated lipids
Coronary Disease D003327 70 associated lipids
Osteosarcoma D012516 50 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Weight Gain D015430 101 associated lipids
Intellectual Disability D008607 13 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Thrombosis D013927 49 associated lipids
Leukemia D007938 74 associated lipids
Glomerulonephritis D005921 35 associated lipids
Cross Infection D003428 9 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Astrocytoma D001254 15 associated lipids
Fever D005334 35 associated lipids
Leishmaniasis D007896 19 associated lipids
Pulmonary Alveolar Proteinosis D011649 5 associated lipids
Thymus Neoplasms D013953 15 associated lipids
HIV Infections D015658 20 associated lipids
Choline Deficiency D002796 16 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Meningeal Neoplasms D008577 5 associated lipids
Atherosclerosis D050197 85 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Insulin Resistance D007333 99 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Weight Loss D015431 56 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Cleft Lip D002971 8 associated lipids
Shwartzman Phenomenon D012790 3 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Yellow Fever D015004 3 associated lipids
Togaviridae Infections D014036 5 associated lipids
Neoplasms, Vascular Tissue D009383 1 associated lipids
Chlamydia Infections D002690 7 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Hepadnaviridae Infections D018347 4 associated lipids
Hepatitis, Viral, Animal D006524 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tetradecanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tetradecanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tetradecanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tetradecanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Tetradecanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tetradecanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Tetradecanoic acid

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Authors Title Published Journal PubMed Link
Novakovic ZM et al. Myristic acid conjugation of [D-Leu-4]-OB3, a biologically active leptin-related synthetic peptide amide, significantly improves its pharmacokinetic profile and efficacy. 2014 Peptides pmid:25453979
Gray NS and Fabbro D Discovery of allosteric BCR-ABL inhibitors from phenotypic screen to clinical candidate. 2014 Meth. Enzymol. pmid:25399646
Takamitsu E et al. Cell-free identification of novel N-myristoylated proteins from complementary DNA resources using bioorthogonal myristic acid analogues. 2014 Anal. Biochem. pmid:25043870
Liu Y et al. Vomeronasal organ lesion disrupts social odor recognition, behaviors and fitness in golden hamsters. 2014 Integr Zool pmid:24952966
Ni K et al. Intrathecal injection of selected peptide Myr-RC-13 attenuates bone cancer pain by inhibiting KIF17 and NR2B expression. 2014 Pharmacol. Biochem. Behav. pmid:24726705
Kroupa T et al. Cost-effective method for the preparation of uniformly labeled myristoylated proteins for NMR measurements. 2014 Protein Expr. Purif. pmid:24662511
Sokmen BB et al. Some monohydroxy tetradecanoic acid isomers as novel urease and elastase inhibitors and as new antioxidants. 2014 Appl. Biochem. Biotechnol. pmid:24189917
Tate EW et al. N-Myristoyltransferase as a potential drug target in malaria and leishmaniasis. 2014 Parasitology pmid:23611109
Mukwevho E and Joseph JS Calmodulin dependent protein kinase II activation by exercise regulates saturated & unsaturated fatty acids and improves some metabolic syndrome markers. 2014 Life Sci. pmid:25046734
Wright CR and Setzer WN Chemical composition of volatiles from Opuntia littoralis, Opuntia ficus-indica, and Opuntia prolifera growing on Catalina Island, California. 2014 Nat. Prod. Res. pmid:24354326
Pavićević ID et al. Fatty acids binding to human serum albumin: Changes of reactivity and glycation level of Cysteine-34 free thiol group with methylglyoxal. 2014 Chem. Biol. Interact. pmid:25451573
Nozawa A and Tozawa Y Modifications of wheat germ cell-free system for functional proteomics of plant membrane proteins. 2014 Methods Mol. Biol. pmid:24136528
Etzold M et al. CDPKs of Cryptosporidium parvum--stage-specific expression in vitro. 2014 Parasitol. Res. pmid:24810092
Ezougou CN et al. Plasmodium falciparum Rab5B is an N-terminally myristoylated Rab GTPase that is targeted to the parasite's plasma and food vacuole membranes. 2014 PLoS ONE pmid:24498355
Yu G and Pichersky E Heterologous expression of methylketone synthase1 and methylketone synthase2 leads to production of methylketones and myristic acid in transgenic plants. 2014 Plant Physiol. pmid:24390393
Díaz R et al. Identification of fatty acids in canine seminal plasma. 2014 Andrologia pmid:23398451
Contreras CM et al. Myristic acid produces anxiolytic-like effects in Wistar rats in the elevated plus maze. 2014 Biomed Res Int pmid:25328885
Sun S et al. Enzymatic epoxidation of soybean oil using ionic liquid as reaction media. 2014 J Oleo Sci pmid:24599105
Thinon E et al. Global profiling of co- and post-translationally N-myristoylated proteomes in human cells. 2014 Nat Commun pmid:25255805
Usami A et al. Characteristic odorants from bailingu oyster mushroom (Pleurotus eryngii var. tuoliensis) and summer oyster mushroom (Pleurotus cystidiosus). 2014 J Oleo Sci pmid:24919476
Baker ST et al. RPM-1 uses both ubiquitin ligase and phosphatase-based mechanisms to regulate DLK-1 during neuronal development. 2014 PLoS Genet. pmid:24810406
Pettit MW et al. Construction and physiochemical characterisation of a multi-composite, potential oral vaccine delivery system (VDS). 2014 Int J Pharm pmid:24680960
Martin DD et al. Identification of a post-translationally myristoylated autophagy-inducing domain released by caspase cleavage of huntingtin. 2014 Hum. Mol. Genet. pmid:24459296
Youn P et al. A myristoylated cell-penetrating peptide bearing a transferrin receptor-targeting sequence for neuro-targeted siRNA delivery. 2014 Mol. Pharm. pmid:24387132
Heinrich F et al. Myristoylation restricts orientation of the GRASP domain on membranes and promotes membrane tethering. 2014 J. Biol. Chem. pmid:24505136
Zhang JC et al. Medelamine C, a new omega-hydroxy alkylamine derivative from endophytic Streptomyces sp. YIM 66142. 2014 Nat Prod Commun pmid:24660474
Kamaraj C et al. Bioassay-guided isolation and characterization of active antiplasmodial compounds from Murraya koenigii extracts against Plasmodium falciparum and Plasmodium berghei. 2014 Parasitol. Res. pmid:24638906
Hagström ÅK et al. A novel fatty acyl desaturase from the pheromone glands of Ctenopseustis obliquana and C. herana with specific Z5-desaturase activity on myristic acid. 2014 J. Chem. Ecol. pmid:24408442
Padovani D et al. High yield production of myristoylated Arf6 small GTPase by recombinant N-myristoyl transferase. 2013 Jan-Mar Small GTPases pmid:23319116
Nafikov RA et al. Sterol regulatory element binding transcription factor 1 (SREBF1) polymorphism and milk fatty acid composition. 2013 J. Dairy Sci. pmid:23403193
Santos S et al. Saturated fatty acids intake in relation to C-reactive protein, adiponectin, and leptin: a population-based study. 2013 Nutrition pmid:23594583
Wang J et al. Interfacial assembly of lipopeptide surfactants on octyltrimethoxysilane-modified silica surface. 2013 Soft Matter pmid:25692456
Zhou X et al. The effect of saturated fatty acids on methanogenesis and cell viability of Methanobrevibacter ruminantium. 2013 Archaea pmid:23710130
Silberstein T et al. Saturated fatty acid composition of human milk in Israel: a comparison between Jewish and Bedouin women. 2013 Isr. Med. Assoc. J. pmid:23781748
Vlach J and Saad JS Trio engagement via plasma membrane phospholipids and the myristoyl moiety governs HIV-1 matrix binding to bilayers. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:23401539
Lu SX and Hrabak EM The myristoylated amino-terminus of an Arabidopsis calcium-dependent protein kinase mediates plasma membrane localization. 2013 Plant Mol. Biol. pmid:23609608
Sooksai S et al. Alterations in growth and fatty acid profiles under stress conditions of Hansenula polymorpha defective in polyunsaturated fatty acid synthesis. 2013 Mol. Biol. Rep. pmid:23645092
Meier A et al. Myristoylated PreS1-domain of the hepatitis B virus L-protein mediates specific binding to differentiated hepatocytes. 2013 Hepatology pmid:23213046
Fragneto G et al. Competition for space between a protein and lipid monolayers. 2013 Colloids Surf B Biointerfaces pmid:23261561
Storck EM et al. Chemical proteomics: a powerful tool for exploring protein lipidation. 2013 Biochem. Soc. Trans. pmid:23356258
Panjarian S et al. Enhanced SH3/linker interaction overcomes Abl kinase activation by gatekeeper and myristic acid binding pocket mutations and increases sensitivity to small molecule inhibitors. 2013 J. Biol. Chem. pmid:23303187
Panjarian S et al. Structure and dynamic regulation of Abl kinases. 2013 J. Biol. Chem. pmid:23316053
Rawat A et al. Fatty acyl chain-dependent but charge-independent association of the SH4 domain of Lck with lipid membranes. 2013 J. Biosci. pmid:23385814
Keller H et al. Multimerizable HIV Gag derivative binds to the liquid-disordered phase in model membranes. 2013 Cell. Microbiol. pmid:23121220
Vijayaraghavan M et al. Suitability of polymer materials for production of pulmonary microparticles using a PGSS supercritical fluid technique: preparation of microparticles using PEG, fatty acids and physical or chemicals blends of PEG and fatty acids. 2013 Int J Pharm pmid:23178217
Chida T et al. N-Myristoylation is essential for protein phosphatases PPM1A and PPM1B to dephosphorylate their physiological substrates in cells. 2013 Biochem. J. pmid:23088624
Russo SB et al. Myristate-derived d16:0 sphingolipids constitute a cardiac sphingolipid pool with distinct synthetic routes and functional properties. 2013 J. Biol. Chem. pmid:23530041
Sharma P et al. Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. 2013 Arch. Biochem. Biophys. pmid:23149273
Burnaevskiy N et al. Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ. 2013 Nature pmid:23535599
Resh MD Covalent lipid modifications of proteins. 2013 Curr. Biol. pmid:23701681
Fukuda N et al. Yeast one-hybrid gγ recruitment system for identification of protein lipidation motifs. 2013 PLoS ONE pmid:23922919
Bastidas AC et al. Influence of N-myristylation and ligand binding on the flexibility of the catalytic subunit of protein kinase A. 2013 Biochemistry pmid:24003983
Doležal M et al. One-step separation of myristoylated and nonmyristoylated retroviral matrix proteins. 2013 Protein Expr. Purif. pmid:24056256
Mathew G et al. Nuclear targeting of dystroglycan promotes the expression of androgen regulated transcription factors in prostate cancer. 2013 Sci Rep pmid:24077328
Hadrévi J et al. Comparative metabolomics of muscle interstitium fluid in human trapezius myalgia: an in vivo microdialysis study. 2013 Eur. J. Appl. Physiol. pmid:24078209
Radi M et al. Allosteric inhibitors of Bcr-Abl: towards novel myristate-pocket binders. 2013 Curr Pharm Biotechnol pmid:22429131
Najumudeen AK et al. Cellular FRET-Biosensors to Detect Membrane Targeting Inhibitors of N-Myristoylated Proteins. 2013 PLoS ONE pmid:23824448
Moriya K et al. Protein N-myristoylation plays a critical role in the endoplasmic reticulum morphological change induced by overexpression of protein Lunapark, an integral membrane protein of the endoplasmic reticulum. 2013 PLoS ONE pmid:24223779
Rawat A and Nagaraj R Covalently attached fatty acyl chains alter the aggregation behavior of an amyloidogenic peptide derived from human β(2)-microglobulin. 2013 J. Pept. Sci. pmid:24243599
Ibragimova MY et al. Biomarkers of Bacillus subtilis total lipids FAME profile under various temperatures and growth phases. 2012 Mar-Apr Dokl. Biochem. Biophys. pmid:22562637
Zhang J et al. Esophageal cancer metabolite biomarkers detected by LC-MS and NMR methods. 2012 PLoS ONE pmid:22291914
Qi Y et al. Cyprinus carpio Decoction Improves Nutrition and Immunity and Reduces Proteinuria through Nephrin and CD2AP Expressions in Rats with Adriamycin-Induced Nephropathy. 2012 Evid Based Complement Alternat Med pmid:22675377
Jangid K et al. A variant quorum sensing system in Aeromonas veronii MTCC 3249. 2012 Sensors (Basel) pmid:22666003
Liu Y et al. IL-1β is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1β autostimulation. 2012 PLoS ONE pmid:22615852
Ittig S et al. The lipopolysaccharide from Capnocytophaga canimorsus reveals an unexpected role of the core-oligosaccharide in MD-2 binding. 2012 PLoS Pathog. pmid:22570611
Mekori YA and Hershko AY T cell-mediated modulation of mast cell function: heterotypic adhesion-induced stimulatory or inhibitory effects. 2012 Front Immunol pmid:22566892
Schaab M et al. Novel regulatory mechanisms for generation of the soluble leptin receptor: implications for leptin action. 2012 PLoS ONE pmid:22545089
Guimarães-Costa AB et al. ETosis: A Microbicidal Mechanism beyond Cell Death. 2012 J Parasitol Res pmid:22536481
Nguyen MT et al. Regulation of chemokine and chemokine receptor expression by PPARγ in adipocytes and macrophages. 2012 PLoS ONE pmid:22529965
Benning UF et al. New aspects of Phloem-mediated long-distance lipid signaling in plants. 2012 Front Plant Sci pmid:22639651
Lv GP et al. Comparison of sterols and fatty acids in two species of Ganoderma. 2012 Chem Cent J pmid:22293530
Ferreira Lde S et al. Apolar compounds in seaweeds from fernando de noronha archipelago (northeastern coast of Brazil). 2012 Int J Anal Chem pmid:22272200
Biester EM et al. Identification of avian wax synthases. 2012 BMC Biochem. pmid:22305293
Yee JK et al. Subcutaneous adipose tissue fatty acid desaturation in adults with and without rare adipose disorders. 2012 Lipids Health Dis pmid:22300160
Patra CR et al. Chemically modified peptides targeting the PDZ domain of GIPC as a therapeutic approach for cancer. 2012 ACS Chem. Biol. pmid:22292614
Albre J et al. Sex pheromone evolution is associated with differential regulation of the same desaturase gene in two genera of leafroller moths. 2012 PLoS Genet. pmid:22291612
Hollander PA Insulin detemir for the treatment of obese patients with type 2 diabetes. 2012 Diabetes Metab Syndr Obes pmid:22291472
Joung S et al. Facile synthesis of uniform large-sized InP nanocrystal quantum dots using tris(tert-butyldimethylsilyl)phosphine. 2012 Nanoscale Res Lett pmid:22289352
Ayyash M et al. Developing a powerful in silico tool for the discovery of novel caspase-3 substrates: a preliminary screening of the human proteome. 2012 BMC Bioinformatics pmid:22269041
Brand S et al. Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors. 2012 J. Med. Chem. pmid:22148754
de Bari O et al. Ezetimibe: its novel effects on the prevention and the treatment of cholesterol gallstones and nonalcoholic Fatty liver disease. 2012 J Lipids pmid:22132342
Montaño M et al. New approaches to assess the transthyretin binding capacity of bioactivated thyroid hormone disruptors. 2012 Toxicol. Sci. pmid:22859314
Cevallos-Cevallos JM et al. GC-MS metabolomic differentiation of selected citrus varieties with different sensitivity to citrus huanglongbing. 2012 Plant Physiol. Biochem. pmid:22326359
Nakata K et al. Targeting of Nphp3 to the primary cilia is controlled by an N-terminal myristoylation site and coiled-coil domains. 2012 Cytoskeleton (Hoboken) pmid:22328406
Preininger AM et al. Myristoylation exerts direct and allosteric effects on Gα conformation and dynamics in solution. 2012 Biochemistry pmid:22329346
Qi D et al. Structure-function analysis of the coiled-coil and leucine-rich repeat domains of the RPS5 disease resistance protein. 2012 Plant Physiol. pmid:22331412
Liu CH and Huang HY Antimicrobial activity of curcumin-loaded myristic acid microemulsions against Staphylococcus epidermidis. 2012 Chem. Pharm. Bull. pmid:22976319
Caccia S et al. Functional analysis of a fatty acid binding protein produced by Aphidius ervi teratocytes. 2012 J. Insect Physiol. pmid:22226822
Srivastava A et al. 14-aminotetradecanoic acid exhibits antioxidant activity and ameliorates xenobiotics-induced cytotoxicity. 2012 Mol. Cell. Biochem. pmid:22198290
Elsøe S et al. Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL. 2012 Atherosclerosis pmid:22204862
Kuban-Jankowska A et al. Activation of hydrogen peroxide to peroxytetradecanoic acid is responsible for potent inhibition of protein tyrosine phosphatase CD45. 2012 PLoS ONE pmid:23300686
Cembran A et al. Conformational equilibrium of N-myristoylated cAMP-dependent protein kinase A by molecular dynamics simulations. 2012 Biochemistry pmid:23205665
Clegg RA et al. Characterisation of the N'1 isoform of the cyclic AMP-dependent protein kinase (PK-A) catalytic subunit in the nematode, Caenorhabditis elegans. 2012 Arch. Biochem. Biophys. pmid:22286028
Pratelli R et al. The ubiquitin E3 ligase LOSS OF GDU2 is required for GLUTAMINE DUMPER1-induced amino acid secretion in Arabidopsis. 2012 Plant Physiol. pmid:22291198
Anachkov SE et al. Determination of the aggregation number and charge of ionic surfactant micelles from the stepwise thinning of foam films. 2012 Adv Colloid Interface Sci pmid:22935484
Ferreira BS et al. A comparison of the physicochemical properties and fatty acid composition of indaiá (Attalea dubia) and Babassu (Orbignya phalerata) oils. 2012 ScientificWorldJournal pmid:22593692
Liu L et al. Carbohydrate-lipid interactions: affinities of methylmannose polysaccharides for lipids in aqueous solution. 2012 Chemistry pmid:22893559
Mo FF et al. Acute hyperglycemia is related to gastrointestinal symptoms in motion sickness: an experimental study. 2012 Physiol. Behav. pmid:21907224
Kowalska A et al. Impact of diets with different proportions of linseed and sunflower oils on the growth, liver histology, immunological and chemical blood parameters, and proximate composition of pikeperch Sander lucioperca (L.). 2012 Fish Physiol. Biochem. pmid:21656178
Aissa I et al. Synthesis of lipophilic tyrosyl esters derivatives and assessment of their antimicrobial and antileishmania activities. 2012 Lipids Health Dis pmid:22264330