Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

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Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Cholestasis D002779 23 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Fetal Resorption D005327 15 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Tay-Sachs Disease D013661 2 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

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Authors Title Published Journal PubMed Link
Cheng K et al. Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line. 2007 Biochem. Pharmacol. pmid:17222808
Fang Y et al. Conjugated bile acids regulate hepatocyte glycogen synthase activity in vitro and in vivo via Galphai signaling. 2007 Mol. Pharmacol. pmid:17200418
Piessen G et al. Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1alpha. 2007 Biochem. J. pmid:17037983
Turner DJ et al. Bile salts induce resistance to apoptosis through NF-kappaB-mediated XIAP expression. 2007 Ann. Surg. pmid:17435549
Martin FP et al. A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model. 2007 Mol. Syst. Biol. pmid:17515922
Czerny B et al. Effect of tamoxifen and raloxifene on the conjugation of bile acids with taurine and glycine in ovariectomized rats. 2006 May-Jun Pharmacol Rep pmid:16845220
Funasaki N et al. Micelle formation of bile salts and zwitterionic derivative as studied by two-dimensional NMR spectroscopy. 2006 Chem. Phys. Lipids pmid:16620799
Petruzzelli M et al. Indomethacin enhances bile salt detergent activity: relevance for NSAIDs-induced gastrointestinal mucosal injury. 2006 Dig. Dis. Sci. pmid:16615001
Clouzeau-Girard H et al. Effects of bile acids on biliary epithelial cell proliferation and portal fibroblast activation using rat liver slices. 2006 Lab. Invest. pmid:16402030
Biagini CP et al. Investigation of the hepatotoxicity profile of chemical entities using Liverbeads and WIF-B9 in vitro models. 2006 Toxicol In Vitro pmid:16504461