Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

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Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Cholestasis D002779 23 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Fetal Resorption D005327 15 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Tay-Sachs Disease D013661 2 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

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Authors Title Published Journal PubMed Link
Shekels LL et al. Tauroursodeoxycholic acid protects in vitro models of human colonic cancer cells from cytotoxic effects of hydrophobic bile acids. 1996 J. Lab. Clin. Med. pmid:8592097
Kidder GW et al. Evaluation of in vivo measurement of transesophageal electrical resistance as an indicator of early experimental esophageal mucosal injury. 1983 J. Lab. Clin. Med. pmid:6619646
Paolini M et al. Mechanism for the prevention of cholestasis involving cytochrome P4503A overexpression. 2000 J. Investig. Med. pmid:10695269
Freinkel RK and Traczyk TN The phospholipases A of epidermis. 1980 J. Invest. Dermatol. pmid:7359009
Baiocchi L et al. Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats. 2003 J. Hepatol. pmid:12547401
van Erpecum KJ et al. Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: soluble pronucleating proteins in gallbladder and hepatic biles. 2001 J. Hepatol. pmid:11682027
Thibault N et al. Effect of tauroursodeoxycholate on actin filament alteration induced by cholestatic agents. A study in isolated rat hepatocyte couplets. 1993 J. Hepatol. pmid:8151096
Moschetta A et al. Hydrophilic bile salts enhance differential distribution of sphingomyelin and phosphatidylcholine between micellar and vesicular phases: potential implications for their effects in vivo. 2001 J. Hepatol. pmid:11394647
Baumgartner U et al. Pattern of bile acid regurgitation and metabolism during perfusion of the bile duct obstructed rat liver. 1995 J. Hepatol. pmid:7790709
Alvarez C and Bass BL Role of transforming growth factor-beta in growth and injury response of the pancreatic duct epithelium in vitro. 1999 Mar-Apr J. Gastrointest. Surg. pmid:10457343