Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

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Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Cholestasis D002779 23 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Fetal Resorption D005327 15 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Tay-Sachs Disease D013661 2 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

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Authors Title Published Journal PubMed Link
Czerny B et al. Effect of tamoxifen and raloxifene on the conjugation of bile acids with taurine and glycine in ovariectomized rats. 2006 May-Jun Pharmacol Rep pmid:16845220
Jin HT et al. Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine. 2011 Pharmacol Rep pmid:22001988
Song IS et al. Contribution of ion-pair complexation with bile salts to the transport of organic cations across LLC-PK1 cell monolayers. 2003 Pharm. Res. pmid:12739767
Alvarez FJ and Stella VJ The role of calcium ions and bile salts on the pancreatic lipase-catalyzed hydrolysis of triglyceride emulsions stabilized with lecithin. 1989 Pharm. Res. pmid:2762220
Song IS et al. Increased affinity to canalicular P-gp via formation of lipophilic ion-pair complexes with endogenous bile salts is associated with mw threshold in hepatobiliary excretion of quaternary ammonium compounds. 2010 Pharm. Res. pmid:20221674
Scriba GK Phenytoin-lipid conjugates: chemical, plasma esterase-mediated, and pancreatic lipase-mediated hydrolysis in vitro. 1993 Pharm. Res. pmid:8415405
Karlgren M et al. In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions. 2012 Pharm. Res. pmid:21861202
Wiedmann TS et al. Ionization and solubilization of 4 alkyl benzoic acids and 4 alkyl anilines in sodium taurodeoxycholate solutions. 1997 Pharm. Res. pmid:9434277
Gasco MR et al. Ion pairs of beta blockers with taurodeoxycholate. 1985 Pharm Acta Helv pmid:2868463
Ammon HV et al. Acid pH enhances the effects of taurodeoxycholate on water and solute transport in the human and rat jejunum. 1987 Pflugers Arch. pmid:3114711