Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

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Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Colitis, Ulcerative D003093 24 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Cholestasis D002779 23 associated lipids
Birth Weight D001724 23 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Tay-Sachs Disease D013661 2 associated lipids
Fetal Resorption D005327 15 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

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Authors Title Published Journal PubMed Link
Santagati NA et al. Analysis of ecdysteroids by micellar electrokinetic chromatography with on-line preconcentration. 2005 J Chromatogr A pmid:16013602
Mrówczynska L et al. Inhibition of MRP1-mediated efflux in human erythrocytes by mono-anionic bile salts. 2005 Sep-Oct Anticancer Res. pmid:16101123
Zhang R et al. Bile salts inhibit growth and induce apoptosis of human esophageal cancer cell line. 2005 World J. Gastroenterol. pmid:16127738
Burkard I et al. Differentiated quantification of human bile acids in serum by high-performance liquid chromatography-tandem mass spectrometry. 2005 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:16182619
Zhao X et al. Protein kinase C modulates the pulmonary inflammatory response in acute pancreatitis. 2006 Respir Physiol Neurobiol pmid:16214426
Ejima D et al. A novel "reverse screening" to identify refolding additives for activin-A. 2006 Protein Expr. Purif. pmid:16226036
Borné J et al. Vesicle formation and other structures in aqueous dispersions of monoolein and sodium oleate. 2003 J Colloid Interface Sci pmid:16256485
Dent P et al. Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes. 2005 Hepatology pmid:16317705
Clouzeau-Girard H et al. Effects of bile acids on biliary epithelial cell proliferation and portal fibroblast activation using rat liver slices. 2006 Lab. Invest. pmid:16402030
Roda A et al. Effect of basic cholane derivatives on intestinal cholic acid metabolism: in vitro and in vivo activity. 1992 J Pharm Sci pmid:1640360
Zhang R et al. Bile salts inhibit growth and induce apoptosis of culture human normal esophageal mucosal epithelial cells. 2005 World J. Gastroenterol. pmid:16425417
Freie AB et al. Val-407 and Ile-408 in the beta5'-loop of pancreatic lipase mediate lipase-colipase interactions in the presence of bile salt micelles. 2006 J. Biol. Chem. pmid:16431912
Venneman NG et al. Indomethacin disrupts the protective effect of phosphatidylcholine against bile salt-induced ileal mucosa injury. 2006 Eur. J. Clin. Invest. pmid:16436092
Mita S et al. Vectorial transport of unconjugated and conjugated bile salts by monolayers of LLC-PK1 cells doubly transfected with human NTCP and BSEP or with rat Ntcp and Bsep. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16474011
Biagini CP et al. Investigation of the hepatotoxicity profile of chemical entities using Liverbeads and WIF-B9 in vitro models. 2006 Toxicol In Vitro pmid:16504461
Totsuka Y et al. Structures and biological properties of DNA adducts derived from N-nitroso bile acid conjugates. 2005 Chem. Res. Toxicol. pmid:16533019
pmid:16600541
Plösch T et al. Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16614371
Petruzzelli M et al. Indomethacin enhances bile salt detergent activity: relevance for NSAIDs-induced gastrointestinal mucosal injury. 2006 Dig. Dis. Sci. pmid:16615001
Funasaki N et al. Micelle formation of bile salts and zwitterionic derivative as studied by two-dimensional NMR spectroscopy. 2006 Chem. Phys. Lipids pmid:16620799
Potter GD et al. Bile acid stimulation of cyclic AMP and ion transport in developing rabbit colon. 1991 J. Pediatr. Gastroenterol. Nutr. pmid:1663997
van Minnen LP et al. Cholesterol crystals enhance and phospholipids protect against pancreatitis induced by hydrophobic bile salts: a rat model study. 2006 Pancreas pmid:16670619
Chen F et al. Chiral capillary electrophoretic separation of amino acids derivatized with 9-fluorenylmethylchloroformate using mixed chiral selectors of beta-cyclodextrin and sodium taurodeoxycholate. 2006 Electrophoresis pmid:16688702
Glew RH et al. A case of nonneurologic Gaucher's disease that biochemically resembles the neurologic types. 1991 J. Neuropathol. Exp. Neurol. pmid:1672707
Taranto MP et al. Effect of bile acid on the cell membrane functionality of lactic acid bacteria for oral administration. 2006 Res. Microbiol. pmid:16730163
Kosters A et al. The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice. 2006 J. Lipid Res. pmid:16741293
Roh JL et al. Effect of acid, pepsin, and bile acid on the stenotic progression of traumatized subglottis. 2006 Am. J. Gastroenterol. pmid:16771935
Orioni B et al. Polymorphic behavior in protein-surfactant mixtures: the water-bovine serum albumin-sodium taurodeoxycholate system. 2006 J Phys Chem B pmid:16800527
Czerny B et al. Effect of tamoxifen and raloxifene on the conjugation of bile acids with taurine and glycine in ovariectomized rats. 2006 May-Jun Pharmacol Rep pmid:16845220
pmid:16872555
Hanus M and Zhorov E Bile acid salt binding with colesevelam HCl is not affected by suspension in common beverages. 2006 J Pharm Sci pmid:16937334
pmid:16944924
Hardison WG et al. Function of rat hepatocyte tight junctions: studies with bile acid infusions. 1991 Am. J. Physiol. pmid:1702935
Piessen G et al. Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1alpha. 2007 Biochem. J. pmid:17037983
Zhao H et al. Role of enteral nutrition supplemented with ebselen and EHEC in pancreatitis-associated multiple organ dysfunction in rats. 2006 Inflamm. Res. pmid:17109069
pmid:17115797
Zhang R et al. [Bile salts induce differentiation in cultured human normal esophageal mucosal epithelial cells]. 2006 Zhonghua Yi Xue Za Zhi pmid:17156647
Fang Y et al. Conjugated bile acids regulate hepatocyte glycogen synthase activity in vitro and in vivo via Galphai signaling. 2007 Mol. Pharmacol. pmid:17200418
Cheng K et al. Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line. 2007 Biochem. Pharmacol. pmid:17222808
Tarpila E et al. The resorption of FITC-dextran 10,000 from the peritoneum in different modifications of bile-induced acute pancreatitis and in bacterial peritonitis. 1991 Nov-Dec Int. J. Pancreatol. pmid:1724008
Carlos MA et al. Epidermal growth factor stimulates chloride transport in primary cultures of weanling and adult rabbit colonocytes. 2007 J. Pediatr. Gastroenterol. Nutr. pmid:17325549
Shi C et al. Potential effects of PKC or protease inhibitors on acute pancreatitis-induced tissue injury in rats. 2007 Vascul. Pharmacol. pmid:17347056
Alrefai WA et al. Taurodeoxycholate modulates apical Cl-/OH- exchange activity in Caco2 cells. 2007 Dig. Dis. Sci. pmid:17387613
pmid:17395011
Eydoux C et al. Further biochemical characterization of human pancreatic lipase-related protein 2 expressed in yeast cells. 2007 J. Lipid Res. pmid:17401110
Turner DJ et al. Bile salts induce resistance to apoptosis through NF-kappaB-mediated XIAP expression. 2007 Ann. Surg. pmid:17435549
Vinokurova LV et al. [Impairment of humoral regulation of exocrine pancreatic function in chronic pancreatitis]. 2007 Ter. Arkh. pmid:17460968
pmid:17506000
Martin FP et al. A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model. 2007 Mol. Syst. Biol. pmid:17515922
Cai SY et al. The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution. 2007 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:17567710
McBride SM et al. Genetic diversity among Enterococcus faecalis. 2007 PLoS ONE pmid:17611618
pmid:17665875
pmid:17675326
Holm R et al. Complexation of tauro- and glyco-conjugated bile salts with three neutral beta-CDs studied by ACE. 2007 Electrophoresis pmid:17893938
Ben Bacha A et al. Proteolytic cleavage of ostrich and turkey pancreatic lipases: production of an active N-terminal domain. 2007 Pancreas pmid:17895836
Cheng BQ et al. Ethyl pyruvate improves survival and ameliorates distant organ injury in rats with severe acute pancreatitis. 2007 Pancreas pmid:17895847
Kanchanapoo J et al. Role of protein kinase C-delta in the age-dependent secretagogue action of bile acids in mammalian colon. 2007 Am. J. Physiol., Cell Physiol. pmid:17898130
Baskin R and Frost LD Bile salt-phospholipid aggregation at submicellar concentrations. 2008 Colloids Surf B Biointerfaces pmid:18035524
Raufman JP et al. Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling. 2008 J. Cell. Physiol. pmid:18064605
Tascilar O et al. Protective effects of erythropoietin against acute lung injury in a rat model of acute necrotizing pancreatitis. 2007 World J. Gastroenterol. pmid:18069756
Schägger H and von Jagow G Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form. 1991 Anal. Biochem. pmid:1812789
Jin HT et al. Polyamine levels in the pancreas and the blood change according to the severity of pancreatitis. 2008 Pancreatology pmid:18235212
Martoni C et al. Investigation of microencapsulated BSH active lactobacillus in the simulated human GI tract. 2007 J. Biomed. Biotechnol. pmid:18273409
Chae HW et al. Effect of ion-pair formation with bile salts on the in vitro cellular transport of berberine. 2008 Arch. Pharm. Res. pmid:18277615
Aromataris EC et al. Store-operated Ca(2+) channels and Stromal Interaction Molecule 1 (STIM1) are targets for the actions of bile acids on liver cells. 2008 Biochim. Biophys. Acta pmid:18342630
pmid:18362845
Axelsson J et al. Initiation of acute pancreatitis by heparan sulphate in the rat. 2008 Scand. J. Gastroenterol. pmid:18365914
Monte MJ et al. Cytosol-nucleus traffic and colocalization with FXR of conjugated bile acids in rat hepatocytes. 2008 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:18467501
Shim WS et al. Decreased secretory transport of a quarternary ammonium, TBuMA, across LLC-PK1 cells by the anionic kidney extract. 2008 Arch. Pharm. Res. pmid:18481027
Matsuoka K et al. Study of thermodynamic parameters for solubilization of plant sterol and stanol in bile salt micelles. 2008 Chem. Phys. Lipids pmid:18544343
Stevens RD et al. Calcium binding by monosulfate esters of taurochenodeoxycholate. 1991 J. Lipid Res. pmid:1856607
Jin HT et al. A polyamine analog bismethylspermine ameliorates severe pancreatitis induced by intraductal infusion of taurodeoxycholate. 2008 Surgery pmid:18571584
Portincasa P et al. Taurodeoxycholate-induced intestinal injury is modulated by oxidative stress-dependent pre-conditioning like mechanisms. 2008 Toxicol. Lett. pmid:18771718
Khafagy el-S et al. Effect of cell-penetrating peptides on the nasal absorption of insulin. 2009 J Control Release pmid:18930084
Castro J et al. A small component of the endoplasmic reticulum is required for store-operated Ca2+ channel activation in liver cells: evidence from studies using TRPV1 and taurodeoxycholic acid. 2009 Biochem. J. pmid:19007332
Shant J et al. Akt-dependent NF-kappaB activation is required for bile acids to rescue colon cancer cells from stress-induced apoptosis. 2009 Exp. Cell Res. pmid:19056378
Murata Y et al. Properties of an oral preparation containing a chitosan salt. 2009 Molecules pmid:19223823
Selvam S et al. A photophysical study on the role of bile salt hydrophobicity in solubilizing amphotericin B aggregates. 2009 J Pharm Sci pmid:19283765
Debellis L et al. The Vibrio cholerae cytolysin promotes chloride secretion from intact human intestinal mucosa. 2009 PLoS ONE pmid:19333391
Bourbon-Freie A et al. Trp-107 and trp-253 account for the increased steady state fluorescence that accompanies the conformational change in human pancreatic triglyceride lipase induced by tetrahydrolipstatin and bile salt. 2009 J. Biol. Chem. pmid:19346257
Nagana Gowda GA et al. Bile acids conjugation in human bile is not random: new insights from (1)H-NMR spectroscopy at 800 MHz. 2009 Lipids pmid:19373503
Yeung LW et al. An analytical method for the determination of perfluorinated compounds in whole blood using acetonitrile and solid phase extraction methods. 2009 J Chromatogr A pmid:19439311
Holm R et al. Thermodynamics and structure of inclusion compounds of tauro- and glyco-conjugated bile salts and beta-cyclodextrin. 2009 Phys Chem Chem Phys pmid:19562137
Keating N et al. Physiological concentrations of bile acids down-regulate agonist induced secretion in colonic epithelial cells. 2009 J. Cell. Mol. Med. pmid:19583809
Jang H et al. Effects of protein concentration and detergent on endotoxin reduction by ultrafiltration. 2009 BMB Rep pmid:19643046
Yu J et al. [Epicatechin abolished TDCA-induced apoptosis in Huh7 cell by inhibiting Bax, p38 MAPK and ROS production]. 2009 Zhongguo Zhong Yao Za Zhi pmid:19673394
Helgason T et al. Impact of surfactant properties on oxidative stability of beta-carotene encapsulated within solid lipid nanoparticles. 2009 J. Agric. Food Chem. pmid:19691283
Fimognari C et al. Apoptosis and modulation of cell cycle control by bile acids in human leukemia T cells. 2009 Ann. N. Y. Acad. Sci. pmid:19723064
Xu Y et al. Freeze-dried grape powder attenuates mitochondria- and oxidative stress-mediated apoptosis in liver cells. 2009 J. Agric. Food Chem. pmid:19754144
pmid:19784950
pmid:19904249
Hong J et al. Role of a novel bile acid receptor TGR5 in the development of oesophageal adenocarcinoma. 2010 Gut pmid:19926617
Hong J et al. Bile acid reflux contributes to development of esophageal adenocarcinoma via activation of phosphatidylinositol-specific phospholipase Cgamma2 and NADPH oxidase NOX5-S. 2010 Cancer Res. pmid:20086178
Jemnitz K et al. Contribution of high basolateral bile salt efflux to the lack of hepatotoxicity in rat in response to drugs inducing cholestasis in human. 2010 Toxicol. Sci. pmid:20147439
Zhou Y et al. Effect of indomethacin on bile acid-phospholipid interactions: implication for small intestinal injury induced by nonsteroidal anti-inflammatory drugs. 2010 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20203063
Sinakos E and Lindor KD Bile acid profiles in intrahepatic cholestasis of pregnancy: is this the solution to the enigma of intrahepatic cholestasis of pregnancy? 2010 Am. J. Gastroenterol. pmid:20203641
Song IS et al. Increased affinity to canalicular P-gp via formation of lipophilic ion-pair complexes with endogenous bile salts is associated with mw threshold in hepatobiliary excretion of quaternary ammonium compounds. 2010 Pharm. Res. pmid:20221674
Ruhaak LR et al. Glycan labeling strategies and their use in identification and quantification. 2010 Anal Bioanal Chem pmid:20225063
Schmidt DR et al. Regulation of bile acid synthesis by fat-soluble vitamins A and D. 2010 J. Biol. Chem. pmid:20233723
Chandrasekar V and Dreyer JL The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in Rats. 2010 Front Behav Neurosci pmid:20407577