Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

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Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Tay-Sachs Disease D013661 2 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Fetal Resorption D005327 15 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Cholestasis D002779 23 associated lipids
Birth Weight D001724 23 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

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Authors Title Published Journal PubMed Link
Lee HK et al. Bile Acid Inhibition of N-type Calcium Channel Currents from Sympathetic Ganglion Neurons. 2012 Korean J. Physiol. Pharmacol. pmid:22416216
Renga B et al. Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis. 2012 PLoS ONE pmid:22291955
Lodola A et al. A catalytic mechanism for cysteine N-terminal nucleophile hydrolases, as revealed by free energy simulations. 2012 PLoS ONE pmid:22389698
Studer E et al. Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes. 2012 Hepatology pmid:21932398
Karlgren M et al. In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions. 2012 Pharm. Res. pmid:21861202
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Kumar M et al. Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases. 2012 Exp Diabetes Res pmid:22611376
Okoli AS et al. Effects of human and porcine bile on the proteome of Helicobacter hepaticus. 2012 Proteome Sci pmid:22533459
Karmakar S et al. TLR4 and NKT cell synergy in immunotherapy against visceral leishmaniasis. 2012 PLoS Pathog. pmid:22511870
Zahiri HR et al. Bile salt supplementation acts via the farnesoid X receptor to alleviate lipopolysaccharide-induced intestinal injury. 2011 Surgery pmid:21878234