Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

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Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Tay-Sachs Disease D013661 2 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Fetal Resorption D005327 15 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Cholestasis D002779 23 associated lipids
Birth Weight D001724 23 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

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Authors Title Published Journal PubMed Link
Jing Yu V et al. Identification of components of grape powder with anti-apoptotic effects. 2011 Toxicol Ind Health pmid:20699283
He J et al. Protective effect of taurohyodeoxycholic acid from Pulvis Fellis Suis on trinitrobenzene sulfonic acid induced ulcerative colitis in mice. 2011 Eur. J. Pharmacol. pmid:21925164
Martin NA et al. Active transport of bile acids decreases mucin 2 in neonatal ileum: implications for development of necrotizing enterocolitis. 2011 PLoS ONE pmid:22162748
Roberts RE et al. The relationship between postprandial bile acid concentration, GLP-1, PYY and ghrelin. 2011 Clin. Endocrinol. (Oxf) pmid:21039722
Song IS et al. Increased affinity to canalicular P-gp via formation of lipophilic ion-pair complexes with endogenous bile salts is associated with mw threshold in hepatobiliary excretion of quaternary ammonium compounds. 2010 Pharm. Res. pmid:20221674
Hong J et al. Role of a novel bile acid receptor TGR5 in the development of oesophageal adenocarcinoma. 2010 Gut pmid:19926617
Lopez-Font I et al. Pancreatic and pulmonary mast cells activation during experimental acute pancreatitis. 2010 World J. Gastroenterol. pmid:20632444
Jemnitz K et al. Contribution of high basolateral bile salt efflux to the lack of hepatotoxicity in rat in response to drugs inducing cholestasis in human. 2010 Toxicol. Sci. pmid:20147439
Perrone EE et al. Dietary bile acid supplementation improves intestinal integrity and survival in a murine model. 2010 J. Pediatr. Surg. pmid:20620329
Gotoh K et al. Bile acid-induced virulence gene expression of Vibrio parahaemolyticus reveals a novel therapeutic potential for bile acid sequestrants. 2010 PLoS ONE pmid:20967223