| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Cholestasis | D002779 | 23 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Fetal Resorption | D005327 | 15 associated lipids |
| Gastroesophageal Reflux | D005764 | 10 associated lipids |
| Gastrointestinal Hemorrhage | D006471 | 27 associated lipids |
| Shock, Hemorrhagic | D012771 | 4 associated lipids |
Taurodeoxycholic acid
Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.
Cross Reference
Introduction
To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Taurodeoxycholic acid?
Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid
PubChem Associated disorders and diseases
What pathways are associated with Taurodeoxycholic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Taurodeoxycholic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Taurodeoxycholic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Taurodeoxycholic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Taurodeoxycholic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Taurodeoxycholic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Taurodeoxycholic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen CC et al. | Prophylactic octreotide reduces the severity of histopathologic changes and hemodynamic shock in early taurodeoxycholate-induced experimental pancreatitis. | 1999 | Proc. Natl. Sci. Counc. Repub. China B | pmid:9949720 |
| Tsyrlov IB et al. | An in vivo-in vitro comparison of the effects of bile acids on the structural organization and functional activity of liver microsomal monooxygenases. | 1978 | Exp. Mol. Pathol. | pmid:99329 |
| Kermanshahi H et al. | Stability of porcine and microbial lipases to conditions that approximate the small intestine of young birds. | 1998 | Poult. Sci. | pmid:9835342 |
| Lang J et al. | Synergistic effect of hydrochloric acid and bile acids on the pars esophageal mucosa of the porcine stomach. | 1998 | Am. J. Vet. Res. | pmid:9736398 |
| Andersson R et al. | Effect of a platelet-activating factor antagonist on pancreatitis-associated gut barrier dysfunction in rats. | 1998 | Pancreas | pmid:9700940 |
| Sandhoff K et al. | Substrate specificity of hexosaminidase A isolated from the liver of a patient with a rare form (AB variant) of infantile GM2 gangliosidosis and control tissues. | 1978 | Adv. Exp. Med. Biol. | pmid:96668 |
| Sreejayan N and von Ritter C | Effect of bile acids on lipid peroxidation: the role of iron. | 1998 | Free Radic. Biol. Med. | pmid:9655521 |
| Alvarez C et al. | Acute effects of bile acids on the pancreatic duct epithelium in vitro. | 1998 | J. Surg. Res. | pmid:9536972 |
| Chen CC et al. | Effects of high dose octreotide on retrograde bile salt-induced pancreatitis in rats. | 1998 | Peptides | pmid:9533643 |
| Duan RD et al. | Effects of ursodeoxycholate and other bile salts on levels of rat intestinal alkaline sphingomyelinase: a potential implication in tumorigenesis. | 1998 | Dig. Dis. Sci. | pmid:9508530 |
| Shibuya N et al. | Co-mutagenicity of glyco- and tauro-deoxycholic acids in the Ames test. | 1997 | Mutat. Res. | pmid:9465909 |
| Roda A et al. | Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat. | 1998 | Hepatology | pmid:9462652 |
| Rao YP et al. | Activation of protein kinase C alpha and delta by bile acids: correlation with bile acid structure and diacylglycerol formation. | 1997 | J. Lipid Res. | pmid:9458268 |
| Riepl RL et al. | Effect of intraduodenal taurodeoxycholate and L-phenylalanine on pancreatic secretion and on gastroenteropancreatic peptide release in man. | 1996 | Eur. J. Med. Res. | pmid:9438149 |
| Wiedmann TS et al. | Ionization and solubilization of 4 alkyl benzoic acids and 4 alkyl anilines in sodium taurodeoxycholate solutions. | 1997 | Pharm. Res. | pmid:9434277 |
| Dabek-Zlotorzynska E and Lai EP | Separation of polynuclear aromatic hydrocarbons by micellar electrokinetic capillary chromatography using sodium taurodeoxycholate modified with organic solvents. | 1996 Jan-Feb | J Capillary Electrophor | pmid:9384762 |
| Donovan JM and Jackson AA | Transbilayer movement of fully ionized taurine-conjugated bile salts depends upon bile salt concentration, hydrophobicity, and membrane cholesterol content. | 1997 | Biochemistry | pmid:9298964 |
| Alvarez C et al. | The pancreatic duct epithelium in vitro: bile acid injury and the effect of epidermal growth factor. | 1997 | Surgery | pmid:9288155 |
| Castelnovo P and Albanesi C | Determination of the enantiomeric purity of N-propionyl-6,7-dimethoxy-2-aminotetralin by cyclodextrin-modified micellar electrokinetic chromatography. | 1997 | Electrophoresis | pmid:9221889 |
| van de Heijning BJ et al. | Membrane cholesterol content of cholesterol/phospholipid vesicles determines the susceptibility to both damage and protection by bile salts: implications for bile physiology. | 1997 | Eur J Gastroenterol Hepatol | pmid:9187880 |
| Loria P et al. | Effect of taurohyodeoxycholic acid on biliary lipid secretion in humans. | 1997 | Hepatology | pmid:9185744 |
| Hu MS et al. | Paracellular phosphate absorption in rat colon: a mechanism for enema-induced hyperphosphatemia. | 1997 | Miner Electrolyte Metab | pmid:9058363 |
| Riepl RL et al. | Mediators of exocrine pancreatic secretion induced by intraduodenal application of bile and taurodeoxycholate in man. | 1997 | Eur. J. Med. Res. | pmid:9049590 |
| Verkade HJ et al. | Interactions between organic anions, micelles and vesicles in model bile systems. | 1996 | Biochem. J. | pmid:9003381 |
| Leveau P et al. | Alterations in intestinal motility and microflora in experimental acute pancreatitis. | 1996 | Int. J. Pancreatol. | pmid:8968867 |
| Bleske BE et al. | Effect of vehicle on the nasal absorption of epinephrine during cardiopulmonary resuscitation. | 1996 Nov-Dec | Pharmacotherapy | pmid:8947976 |
| Okido M et al. | Influence of phospholipid on bile salt binding to calcium hydroxyapatite and on the poisoning of nascent hydroxyapatite crystals. | 1996 | Liver | pmid:8938633 |
| Beijersten I and Westerlund D | Capillary zone electrophoresis and micellar electrokinetic chromatography, with taurodeoxycholate as micellar agent, of protein kinase A peptide substrates. | 1996 | Electrophoresis | pmid:8907534 |
| Buts JP et al. | Intestinal transport of calcium in rat biliary cirrhosis. | 1996 | Pediatr. Res. | pmid:8888279 |
| Van Erpecum KJ et al. | Effects of bile salt hydrophobicity on crystallization of cholesterol in model bile. | 1996 | Eur. J. Clin. Invest. | pmid:8864423 |
| DeLong LJ and Nichols JW | Time-resolved fluorescence anisotropy of fluorescent-labeled lysophospholipid and taurodeoxycholate aggregates. | 1996 | Biophys. J. | pmid:8785303 |
| Trawick JD et al. | Rat hepatoma L35 cells, a liver-differentiated cell line, display resistance to bile acid repression of cholesterol 7 alpha-hydroxylase. | 1996 | J. Lipid Res. | pmid:8728321 |
| Heuman DM et al. | Adsorption of mixtures of bile salt taurine conjugates to lecithin-cholesterol membranes: implications for bile salt toxicity and cytoprotection. | 1996 | J. Lipid Res. | pmid:8728319 |
| Oude Elferink RP et al. | Uncoupling of biliary phospholipid and cholesterol secretion in mice with reduced expression of mdr2 P-glycoprotein. | 1996 | J. Lipid Res. | pmid:8725158 |
| Smit JW et al. | Does the HMG-CoA reductase inhibitor pravastatin influence nucleation of cholesterol crystals in supersaturated model bile? | 1996 | Eur J Gastroenterol Hepatol | pmid:8724016 |
| Albalak A et al. | Effects of submicellar bile salt concentrations on biological membrane permeability to low molecular weight non-ionic solutes. | 1996 | Biochemistry | pmid:8672496 |
| Muraca M et al. | Protective effect of tauroursodeoxycholate against acute gastric mucosal injury induced by hydrophobic bile salts. | 1996 | Dig. Dis. Sci. | pmid:8654150 |
| Narayanan VS and Storch J | Fatty acid transfer in taurodeoxycholate mixed micelles. | 1996 | Biochemistry | pmid:8652524 |
| Shekels LL et al. | Tauroursodeoxycholic acid protects in vitro models of human colonic cancer cells from cytotoxic effects of hydrophobic bile acids. | 1996 | J. Lab. Clin. Med. | pmid:8592097 |
| Armstrong DN et al. | Bile salt inhibition of motility in the isolated perfused rabbit terminal ileum. | 1993 | Gut | pmid:8491394 |
| van Tilbeurgh H et al. | Interfacial activation of the lipase-procolipase complex by mixed micelles revealed by X-ray crystallography. | 1993 | Nature | pmid:8479519 |
| Hu MS et al. | Bile salts and ileal calcium transport in rats: a neglected factor in intestinal calcium absorption. | 1993 | Am. J. Physiol. | pmid:8447415 |
| Holmes EH and Macher BA | Specificity of fucose transfer to GlcNAc residues of extended chain neolacto-series glycolipids catalyzed by human alpha 1-->3fucosyltransferases: effect of the lipidic environment on the myeloid enzyme form. | 1993 | Arch. Biochem. Biophys. | pmid:8442661 |
| Scriba GK | Phenytoin-lipid conjugates: chemical, plasma esterase-mediated, and pancreatic lipase-mediated hydrolysis in vitro. | 1993 | Pharm. Res. | pmid:8415405 |
| Girardet JM et al. | Study of mechanism of lipolysis inhibition by bovine milk proteose-peptone component 3. | 1993 | J. Dairy Sci. | pmid:8408864 |
| Dakka T et al. | Luminal bile salts and neurotensin release in the isolated vascularly perfused rat jejuno-ileum. | 1994 | Endocrinology | pmid:8299558 |
| Field M | Bile salt-induced diarrhea: the cellular mechanism. | 1993 | J. Clin. Invest. | pmid:8227323 |
| Pak JM and Lee SS | Vasoactive effects of bile salts in cirrhotic rats: in vivo and in vitro studies. | 1993 | Hepatology | pmid:8225224 |
| Tripodi AS et al. | In vitro and in vivo mutagenicity studies on taurohyodeoxycholic acid. | 1993 | Arzneimittelforschung | pmid:8216450 |
| Feletti F et al. | Reproductive toxicity of taurohyodeoxycholic acid. | 1993 | Arzneimittelforschung | pmid:8216449 |
| Feletti F et al. | Chronic toxicity of taurohyodeoxycholic acid in dogs. | 1993 | Arzneimittelforschung | pmid:8216448 |
| De Bernardi di Valserra M et al. | Chronic toxicity of taurohyodeoxycholic acid in rats. | 1993 | Arzneimittelforschung | pmid:8216447 |
| Heuman DM and Bajaj R | Ursodeoxycholate conjugates protect against disruption of cholesterol-rich membranes by bile salts. | 1994 | Gastroenterology | pmid:8174892 |
| Thibault N et al. | Effect of tauroursodeoxycholate on actin filament alteration induced by cholestatic agents. A study in isolated rat hepatocyte couplets. | 1993 | J. Hepatol. | pmid:8151096 |
| O'Leary DP | Artificial bile inhibits bile salt-induced gallbladder glycoprotein release in vitro. | 1994 | Hepatology | pmid:8119706 |
| Kupper J et al. | The flagellar bundle of Halobacterium salinarium is inserted into a distinct polar cap structure. | 1994 | J. Bacteriol. | pmid:8051038 |
| Dulfer WJ and Govers HA | Solubility and micelle-water partitioning of polychlorinated biphenyls in solutions of bile salt micelles. | 1995 | Chemosphere | pmid:7874475 |
| Aldini R et al. | Hepatic uptake and intestinal absorption of bile acids in the rabbit. | 1994 | Eur. J. Clin. Invest. | pmid:7851470 |
| Long MA et al. | Structural characterization of the micelle-vesicle transition in lecithin-bile salt solutions. | 1994 | Biophys. J. | pmid:7819505 |
| Sanabria JR et al. | Effect of deoxycholate on immunoglobulin G concentration in bile: studies in humans and pigs. | 1995 | Hepatology | pmid:7806157 |
| Klinkspoor JH et al. | Model bile and bile salts accelerate mucin secretion by cultured dog gallbladder epithelial cells. | 1995 | Gastroenterology | pmid:7797024 |
| Baumgartner U et al. | Pattern of bile acid regurgitation and metabolism during perfusion of the bile duct obstructed rat liver. | 1995 | J. Hepatol. | pmid:7790709 |
| Alvaro D et al. | Functional and ultrastructural features of ethanol/bile salts interaction in the isolated perfused rat liver. | 1995 | Hepatology | pmid:7705787 |
| Devor DC et al. | Taurodeoxycholate activates potassium and chloride conductances via an IP3-mediated release of calcium from intracellular stores in a colonic cell line (T84) | 1993 | J. Clin. Invest. | pmid:7693758 |
| Gargouri Y et al. | Kinetic behaviour of pancreatic lipase in five species using emulsions and monomolecular films of synthetic glycerides. | 1995 | Biochim. Biophys. Acta | pmid:7647098 |
| Aumatell A and Wells RJ | Determination of a cardiac antiarrhythmic, tricyclic antipsychotics and antidepressants in human and animal urine by micellar electrokinetic capillary chromatography using a bile salt. | 1995 | J. Chromatogr. B, Biomed. Appl. | pmid:7581909 |
| Kullak-Ublick GA et al. | Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver. | 1995 | Gastroenterology | pmid:7557095 |
| Carsberg CJ et al. | Ultraviolet radiation-induced melanogenesis in human melanocytes. Effects of modulating protein kinase C. | 1994 | J. Cell. Sci. | pmid:7531203 |
| Riepl RL et al. | Effect of intraduodenal bile and taurodeoxycholate on exocrine pancreatic secretion and on plasma levels of vasoactive intestinal polypeptide and somatostatin in man. | 1994 | Pancreas | pmid:7509061 |
| Gustavsson J et al. | Translocation of insulin-regulated glucose transporter is stimulated by long-chain 1,2-diacylglycerol in rat adipocytes. | 1995 | Exp. Cell Res. | pmid:7493643 |
| Kobayashi T and Suzuki K | A taurodeoxycholate-activated galactosylceramidase in the murine intestine. | 1981 | J. Biol. Chem. | pmid:7451495 |
| Buchanan CR et al. | Choleretic effects of taurocholate and taurodeoxycholate in the guinea-pig [proceedings]. | 1978 | J. Physiol. (Lond.) | pmid:745096 |
| Charles M et al. | Small-angle neutron scattering study of the association between porcine pancreatic colipase and taurodeoxycholate micelles. | 1980 | J. Mol. Biol. | pmid:7441738 |
| Granon S and Sémériva M | Effect of taurodeoxycholate, colipase and temperature on the interfacial inactivation of porcine pancreatic lipase. | 1980 | Eur. J. Biochem. | pmid:7439178 |
| Thomson AB | Unidirectional flux rate of cholesterol and fatty acids into the intestine of rats with drug-induced diabetes mellitus: effect of variations in the effective resistance of the unstirred water layer and the bile acid micelle. | 1980 | J. Lipid Res. | pmid:7419982 |
| Murakami K et al. | Partial purification and characterization of taurodeoxycholate 7 alpha-monooxygenase. | 1980 | Biochem. Biophys. Res. Commun. | pmid:7396953 |
| Erlanson-Albertsson C | Measurement of the binding of colipase to a triacylglycerol substrate. | 1980 | Biochim. Biophys. Acta | pmid:7370284 |
| Freinkel RK and Traczyk TN | The phospholipases A of epidermis. | 1980 | J. Invest. Dermatol. | pmid:7359009 |
| Momsen WE and Brockman HL | Purification of pancreatic lipase via its affinity for bile salts and apolar surfaces. | 1978 | J. Lipid Res. | pmid:731125 |
| Harmon JW and Lewis C | Effects of intravenous 16,16 dimethyl prostaglandin E2 on bile salt induced injury to gastric mucosa in canine Heidenhain pouches. | 1981 | Prostaglandins | pmid:7302256 |
| Canioni P et al. | Circular dichroism study of horse colipase interaction with bile salt. | 1981 | Biochim. Biophys. Acta | pmid:7295779 |
| Thomson AB and O'Brien BD | Uptake of cholesterol into rabbit jejunum using three in vitro techniques: importance of bile acid micelles and unstirred layer resistance. | 1981 | Am. J. Physiol. | pmid:7282936 |
| Batta AK et al. | Thin-layer chromatographic separation of conjugates of ursodeoxycholic acid from those of litho-, chenodeoxy-, deoxy-, and cholic acids. | 1981 | J. Lipid Res. | pmid:7276746 |
| Murakami K and Okuda K | Purification and characterization of taurodeoxycholate 7 alpha-monooxygenase in rat liver. | 1981 | J. Biol. Chem. | pmid:7263676 |
| Wieloch T et al. | Porcine pancreatic procolipase and its trypsin-activated form: lipid binding and lipase activation on monomolecular films. | 1981 | FEBS Lett. | pmid:7262313 |
| Levy E et al. | Characterization of gastric lipolytic activity. | 1981 | Biochim. Biophys. Acta | pmid:7248327 |
| Li SC et al. | A protein activator for the enzymic hydrolysis of GM2 ganglioside. | 1981 | J. Biol. Chem. | pmid:7240201 |
| Borgström B and Wollesen C | Effect of fenfluramine and related compounds on the pancreatic colipase/lipase system. | 1981 | FEBS Lett. | pmid:7238862 |
| Ramakrishnan VR et al. | Effects of sphincter of Oddi bypass on bile acid metabolism in fed and fasted intact and cholecystectomized dogs. | 1981 | Digestion | pmid:7215717 |
| Sauve P and Desnuelle P | Interactions of pancreatic colipase with taurodeoxycholate--oleate mixtures above the critical micelle concentration. | 1980 | FEBS Lett. | pmid:7215549 |
| Cozzone PJ et al. | 360-MHz nuclear magnetic resonance and laser photochemically induced dynamic nuclear polarization studies of bile salt interaction with porcine colipase A. | 1981 | Eur. J. Biochem. | pmid:7215346 |
| Sari H et al. | Role of tyrosine residues in the binding of colipase to taurodeoxycholate micelles. | 1978 | FEBS Lett. | pmid:720615 |
| Behnke WD | The reaction of porcine colipase a with tetranitromethane. Generation of extrinsic cotton effects in the visible region. | 1982 | Biochim. Biophys. Acta | pmid:7171613 |
| Borgström B | The temperature-dependent interfacial inactivation of porcine pancreatic lipase. Effect of colipase and bile salts. | 1982 | Biochim. Biophys. Acta | pmid:7126621 |
| Noshiro M et al. | The involvement of cytochrome b5 in 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol 25-hydroxylation and taurodeoxycholate 7 alpha-hydroxylation of rat liver. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7115387 |
| Brown AJ and Kolattukudy PE | Evidence that pancreatic lipase is responsible for the hydrolysis of cutin, a biopolyester present in mammalian diet, and the role of bile salt and colipase in this hydrolysis. | 1978 | Arch. Biochem. Biophys. | pmid:708069 |
| Gaskin KJ et al. | Colipase and maximally activated pancreatic lipase in normal subjects and patients with steatorrhea. | 1982 | J. Clin. Invest. | pmid:7056854 |
| Chalifour R and Kanfer JN | Fatty acid activation and temperature perturbation of rat brain microsomal phospholipase D. | 1982 | J. Neurochem. | pmid:7045286 |
| Shefer S et al. | Metabolism of iso-bile acids in the rat. | 1982 | J. Biol. Chem. | pmid:7035450 |
| Lillemoe KD et al. | Role of the components of the gastroduodenal contents in experimental acid esophagitis. | 1982 | Surgery | pmid:6808683 |