Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

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Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Cholestasis D002779 23 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Fetal Resorption D005327 15 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

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Authors Title Published Journal PubMed Link
Potter GD et al. Taurodeoxycholate and the developing rabbit distal colon: absence of secretory effect. 1987 Am. J. Physiol. pmid:3477961
Hardison WG et al. Function of rat hepatocyte tight junctions: studies with bile acid infusions. 1991 Am. J. Physiol. pmid:1702935
Anwer MS et al. Ursodeoxycholate-induced changes in hepatic Na+-H+ exchange and biliary HCO3- excretion. 1989 Am. J. Physiol. pmid:2551181
Goldstein JL et al. Effects of taurine-conjugated bile salts on ionic transport of the rabbit esophageal mucosa. 1986 Am. J. Physiol. pmid:3777173
Hu MS et al. Bile salts and ileal calcium transport in rats: a neglected factor in intestinal calcium absorption. 1993 Am. J. Physiol. pmid:8447415
Hoffman NE et al. Bile acid structure and biliary lipid secretion. II. A comparison of three hydroxy and two keto bile acids. 1978 Am. J. Physiol. pmid:665767
Okolo C et al. Effects of bile acids on dog pancreatic duct epithelial cell secretion and monolayer resistance. 2002 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12381517
Plösch T et al. Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16614371
Cao W et al. Expression of bile acid receptor TGR5 in gastric adenocarcinoma. 2013 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:23238937
Mita S et al. Vectorial transport of unconjugated and conjugated bile salts by monolayers of LLC-PK1 cells doubly transfected with human NTCP and BSEP or with rat Ntcp and Bsep. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16474011