Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

Cross Reference

Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Tay-Sachs Disease D013661 2 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Fetal Resorption D005327 15 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Cholestasis D002779 23 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

Download all related citations
Per page 10 20 50 100 | Total 449
Authors Title Published Journal PubMed Link
McBride SM et al. Genetic diversity among Enterococcus faecalis. 2007 PLoS ONE pmid:17611618
Alrefai WA et al. Taurodeoxycholate modulates apical Cl-/OH- exchange activity in Caco2 cells. 2007 Dig. Dis. Sci. pmid:17387613
Cheng BQ et al. Ethyl pyruvate improves survival and ameliorates distant organ injury in rats with severe acute pancreatitis. 2007 Pancreas pmid:17895847
Kanchanapoo J et al. Role of protein kinase C-delta in the age-dependent secretagogue action of bile acids in mammalian colon. 2007 Am. J. Physiol., Cell Physiol. pmid:17898130
Cai SY et al. The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution. 2007 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:17567710
Vinokurova LV et al. [Impairment of humoral regulation of exocrine pancreatic function in chronic pancreatitis]. 2007 Ter. Arkh. pmid:17460968
Shi C et al. Potential effects of PKC or protease inhibitors on acute pancreatitis-induced tissue injury in rats. 2007 Vascul. Pharmacol. pmid:17347056
Tascilar O et al. Protective effects of erythropoietin against acute lung injury in a rat model of acute necrotizing pancreatitis. 2007 World J. Gastroenterol. pmid:18069756
Martoni C et al. Investigation of microencapsulated BSH active lactobacillus in the simulated human GI tract. 2007 J. Biomed. Biotechnol. pmid:18273409
Carlos MA et al. Epidermal growth factor stimulates chloride transport in primary cultures of weanling and adult rabbit colonocytes. 2007 J. Pediatr. Gastroenterol. Nutr. pmid:17325549
Eydoux C et al. Further biochemical characterization of human pancreatic lipase-related protein 2 expressed in yeast cells. 2007 J. Lipid Res. pmid:17401110
Piessen G et al. Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1alpha. 2007 Biochem. J. pmid:17037983
Turner DJ et al. Bile salts induce resistance to apoptosis through NF-kappaB-mediated XIAP expression. 2007 Ann. Surg. pmid:17435549
Holm R et al. Complexation of tauro- and glyco-conjugated bile salts with three neutral beta-CDs studied by ACE. 2007 Electrophoresis pmid:17893938
Martin FP et al. A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model. 2007 Mol. Syst. Biol. pmid:17515922
Czerny B et al. Effect of tamoxifen and raloxifene on the conjugation of bile acids with taurine and glycine in ovariectomized rats. 2006 May-Jun Pharmacol Rep pmid:16845220
Hanus M and Zhorov E Bile acid salt binding with colesevelam HCl is not affected by suspension in common beverages. 2006 J Pharm Sci pmid:16937334
Zhang R et al. [Bile salts induce differentiation in cultured human normal esophageal mucosal epithelial cells]. 2006 Zhonghua Yi Xue Za Zhi pmid:17156647
Freie AB et al. Val-407 and Ile-408 in the beta5'-loop of pancreatic lipase mediate lipase-colipase interactions in the presence of bile salt micelles. 2006 J. Biol. Chem. pmid:16431912
Funasaki N et al. Micelle formation of bile salts and zwitterionic derivative as studied by two-dimensional NMR spectroscopy. 2006 Chem. Phys. Lipids pmid:16620799
Plösch T et al. Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16614371
Ejima D et al. A novel "reverse screening" to identify refolding additives for activin-A. 2006 Protein Expr. Purif. pmid:16226036
Zhao X et al. Protein kinase C modulates the pulmonary inflammatory response in acute pancreatitis. 2006 Respir Physiol Neurobiol pmid:16214426
Venneman NG et al. Indomethacin disrupts the protective effect of phosphatidylcholine against bile salt-induced ileal mucosa injury. 2006 Eur. J. Clin. Invest. pmid:16436092
Zhao H et al. Role of enteral nutrition supplemented with ebselen and EHEC in pancreatitis-associated multiple organ dysfunction in rats. 2006 Inflamm. Res. pmid:17109069
Orioni B et al. Polymorphic behavior in protein-surfactant mixtures: the water-bovine serum albumin-sodium taurodeoxycholate system. 2006 J Phys Chem B pmid:16800527
Roh JL et al. Effect of acid, pepsin, and bile acid on the stenotic progression of traumatized subglottis. 2006 Am. J. Gastroenterol. pmid:16771935
Chen F et al. Chiral capillary electrophoretic separation of amino acids derivatized with 9-fluorenylmethylchloroformate using mixed chiral selectors of beta-cyclodextrin and sodium taurodeoxycholate. 2006 Electrophoresis pmid:16688702
Taranto MP et al. Effect of bile acid on the cell membrane functionality of lactic acid bacteria for oral administration. 2006 Res. Microbiol. pmid:16730163
Kosters A et al. The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice. 2006 J. Lipid Res. pmid:16741293
Petruzzelli M et al. Indomethacin enhances bile salt detergent activity: relevance for NSAIDs-induced gastrointestinal mucosal injury. 2006 Dig. Dis. Sci. pmid:16615001
Clouzeau-Girard H et al. Effects of bile acids on biliary epithelial cell proliferation and portal fibroblast activation using rat liver slices. 2006 Lab. Invest. pmid:16402030
Biagini CP et al. Investigation of the hepatotoxicity profile of chemical entities using Liverbeads and WIF-B9 in vitro models. 2006 Toxicol In Vitro pmid:16504461
Mita S et al. Vectorial transport of unconjugated and conjugated bile salts by monolayers of LLC-PK1 cells doubly transfected with human NTCP and BSEP or with rat Ntcp and Bsep. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16474011
van Minnen LP et al. Cholesterol crystals enhance and phospholipids protect against pancreatitis induced by hydrophobic bile salts: a rat model study. 2006 Pancreas pmid:16670619
Mrówczynska L et al. Inhibition of MRP1-mediated efflux in human erythrocytes by mono-anionic bile salts. 2005 Sep-Oct Anticancer Res. pmid:16101123
Trotta M et al. Solid lipid micro-particles carrying insulin formed by solvent-in-water emulsion-diffusion technique. 2005 Int J Pharm pmid:15620868
Santagati NA et al. Analysis of ecdysteroids by micellar electrokinetic chromatography with on-line preconcentration. 2005 J Chromatogr A pmid:16013602
Song KH et al. Enhanced intestinal absorption of salmon calcitonin (sCT) from proliposomes containing bile salts. 2005 J Control Release pmid:15979756
Totsuka Y et al. Structures and biological properties of DNA adducts derived from N-nitroso bile acid conjugates. 2005 Chem. Res. Toxicol. pmid:16533019
Burkard I et al. Differentiated quantification of human bile acids in serum by high-performance liquid chromatography-tandem mass spectrometry. 2005 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:16182619
Zhang R et al. Bile salts inhibit growth and induce apoptosis of culture human normal esophageal mucosal epithelial cells. 2005 World J. Gastroenterol. pmid:16425417
Khurana S et al. Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M(3) receptor-dependent. 2005 Eur. J. Pharmacol. pmid:15964566
Leveau P et al. Severity of pancreatitis-associated gut barrier dysfunction is reduced following treatment with the PAF inhibitor lexipafant. 2005 Biochem. Pharmacol. pmid:15826603
Dent P et al. Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes. 2005 Hepatology pmid:16317705
Pomponio R et al. Microemulsion electrokinetic chromatography of corticosteroids. Effect of surfactants and cyclodextrins on the separation selectivity. 2005 J Chromatogr A pmid:16013593
Jurek D et al. Bile acid induced gene expression in LT97 colonic adenoma cells. 2005 Food Chem. Toxicol. pmid:15582199
Zhang R et al. Bile salts inhibit growth and induce apoptosis of human esophageal cancer cell line. 2005 World J. Gastroenterol. pmid:16127738
Matyash V et al. Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16. 2004 PLoS Biol. pmid:15383841
Fang Y et al. Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes. 2004 Hepatology pmid:15382121
Rani K et al. Measurement of bile acid in serum and bile with arylamine-glass-bound 3alpha-hydroxysteroid dehydrogenase and diaphorase. 2004 Anal. Biochem. pmid:15301946
Aeed PA et al. Effect of membrane perturbants on the activity and phase distribution of inositol phosphorylceramide synthase; development of a novel assay. 2004 Biochemistry pmid:15222759
Chen CC et al. Effects of nitric oxide synthase inhibitors on retrograde bile salt-induced pancreatitis rats. 2004 J Chin Med Assoc pmid:15077884
Campbell NB et al. Physiological concentrations of bile salts inhibit recovery of ischemic-injured porcine ileum. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15087278
Mühlbauer M et al. Differential effects of deoxycholic acid and taurodeoxycholic acid on NF-kappa B signal transduction and IL-8 gene expression in colonic epithelial cells. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:14726307
Kubitz R et al. Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase. 2004 Gastroenterology pmid:14762791
Yamaguchi J et al. Taurodeoxycholate increases intestinal epithelial cell proliferation through c-myc expression. 2004 Surgery pmid:14739857
Toledo A et al. Taurodeoxycholate stimulates intestinal cell proliferation and protects against apoptotic cell death through activation of NF-kappaB. 2004 Dig. Dis. Sci. pmid:15573924
Voronina SG et al. Effects of secretagogues and bile acids on mitochondrial membrane potential of pancreatic acinar cells: comparison of different modes of evaluating DeltaPsim. 2004 J. Biol. Chem. pmid:15084611
Worku ML et al. Chemotactic response of Helicobacter pylori to human plasma and bile. 2004 J. Med. Microbiol. pmid:15272070
Murata Y et al. Adsorption of bile acid by chitosan-orotic acid salt and its application as an oral preparation. 2004 Chem. Pharm. Bull. pmid:15467231
Camarota LM et al. Carboxyl ester lipase cofractionates with scavenger receptor BI in hepatocyte lipid rafts and enhances selective uptake and hydrolysis of cholesteryl esters from HDL3. 2004 J. Biol. Chem. pmid:15105424
Lim HJ et al. Isolation of cholesterol-lowering lactic acid bacteria from human intestine for probiotic use. 2004 J. Vet. Sci. pmid:15613825
Figge A et al. Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis. 2004 J. Biol. Chem. pmid:14570929
Moschetta A et al. Basolateral Ca2+-dependent K+-channels play a key role in Cl- secretion induced by taurodeoxycholate from colon mucosa. 2003 Mar-Apr Biol. Cell pmid:12799067
Strauch ED et al. NF-kappaB regulates intestinal epithelial cell and bile salt-induced migration after injury. 2003 Ann. Surg. pmid:12677145
Song IS et al. Contribution of ion-pair complexation with bile salts to the transport of organic cations across LLC-PK1 cell monolayers. 2003 Pharm. Res. pmid:12739767
Um JY et al. In vitro cellular interaction and absorption of dispersed cubic particles. 2003 Int J Pharm pmid:12593938
Baiocchi L et al. Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats. 2003 J. Hepatol. pmid:12547401
Baumgartner U et al. Repetitive short-term bile duct obstruction and relief causes reproducible and reversible bile acid regurgitation. 2003 J. Surg. Res. pmid:12697405
Chen W and Gluud C Bile acids for primary sclerosing cholangitis. 2003 Cochrane Database Syst Rev pmid:12804480
Borné J et al. Vesicle formation and other structures in aqueous dispersions of monoolein and sodium oleate. 2003 J Colloid Interface Sci pmid:16256485
Strauch ED et al. Bile salts regulate intestinal epithelial cell migration by nuclear factor-kappa B-induced expression of transforming growth factor-beta. 2003 J. Am. Coll. Surg. pmid:14644286
Komichi D et al. Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes. 2003 Dig. Dis. Sci. pmid:14714619
Haraldsen P et al. Multimodal management - of value in fulminant acute pancreatitis? 2003 Pancreatology pmid:12649560
Sánchez Pozzi EJ et al. Ursodeoxycholate reduces ethinylestradiol glucuronidation in the rat: role in prevention of estrogen-induced cholestasis. 2003 J. Pharmacol. Exp. Ther. pmid:12663690
Smídková M et al. Effect of drugs on cholesterol crystallization in an artificial bile model and relation of this effect to drug binding to albumin. 2003 Fundam Clin Pharmacol pmid:12803572
Lamireau T et al. Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion. 2003 Life Sci. pmid:12527037
Artusi M et al. Buccal delivery of thiocolchicoside: in vitro and in vivo permeation studies. 2003 Int J Pharm pmid:12480286
Aubert E et al. Site-directed mutagenesis of the basic N-terminal cluster of pancreatic bile salt-dependent lipase. Functional significance. 2002 J. Biol. Chem. pmid:12110666
Piepoli AL et al. Tauroursodeoxycholic acid reduces damaging effects of taurodeoxycholic acid on fundus gastric mucosa. 2002 Arch. Physiol. Biochem. pmid:12221520
Okolo C et al. Effects of bile acids on dog pancreatic duct epithelial cell secretion and monolayer resistance. 2002 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12381517
Pandak WM et al. Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in primary cultures of rat hepatocytes. 2002 Hepatology pmid:12029625
Yapoudjian S et al. Surface fluorescence resonance energy transfer studies on interfacial adsorption of Thermomyces (humicola) lanuginosa lipase, using monomolecular films of cis-parinaric acid. 2002 Biopolymers pmid:12209462
Voronina S et al. Bile acids induce calcium signals in mouse pancreatic acinar cells: implications for bile-induced pancreatic pathology. 2002 J. Physiol. (Lond.) pmid:11927668
Graf D et al. Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner. 2002 Gastroenterology pmid:11984527
Hartmann G et al. Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia. 2002 J. Pharmacol. Exp. Ther. pmid:12235261
Carubbi F et al. Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line. 2002 Biochim. Biophys. Acta pmid:11923098
Venneman NG et al. Effects of hydrophobic and hydrophilic bile salt mixtures on cholesterol crystallization in model biles. 2002 Biochim. Biophys. Acta pmid:12117566
Lin JM et al. Comparison of three different anionic surfactants for the separation of hydrophobic compounds by nonaqueous capillary electrophoresis. 2002 Electrophoresis pmid:11870742
Rao YP et al. Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes. 2002 Hepatology pmid:11826403
Dib M et al. Role of mast cells in the development of pancreatitis-induced multiple organ dysfunction. 2002 Br J Surg pmid:11856129
Strauch ED et al. Bile salt stimulates intestinal epithelial cell migration through TGFbeta after wounding. 2001 J. Surg. Res. pmid:11319879
Crandall WV and Lowe ME Colipase residues Glu64 and Arg65 are essential for normal lipase-mediated fat digestion in the presence of bile salt micelles. 2001 J. Biol. Chem. pmid:11278590
Bani D et al. The vasorelaxant hormone relaxin induces changes in liver sinusoid microcirculation: a morphologic study in the rat. 2001 J. Endocrinol. pmid:11739020
Baumgartner U et al. Colchicine inhibits taurodeoxycholate transport in pericentral but not in periportal hepatocytes. 2001 Biochim. Biophys. Acta pmid:11420119
Tiss A et al. Effects of gum arabic on lipase interfacial binding and activity. 2001 Anal. Biochem. pmid:11412003
Torchia EC et al. Differential modulation of cellular death and survival pathways by conjugated bile acids. 2001 BMC Biochem. pmid:11707155
Kahn ME et al. Possible mechanisms of diarrheal side effects associated with the use of a novel chemotherapeutic agent, flavopiridol. 2001 Clin. Cancer Res. pmid:11234889
Hino A et al. Effects of deoxycholic acid and its epimers on lipid peroxidation in isolated rat hepatocytes. 2001 J. Biochem. pmid:11328589